TY - JOUR T1 - Comparison of sodium hypochlorite and sodium dichloroisocyanurate disinfectants: neutralization by serum. A1 - Coates,D, PY - 1988/1/1/pubmed PY - 1988/1/1/medline PY - 1988/1/1/entrez SP - 60 EP - 7 JF - The Journal of hospital infection JO - J Hosp Infect VL - 11 IS - 1 N2 - A comparison has been made of the activity against Pseudomonas aeruginosa of sodium hypochlorite (NaOCl) and sodium dichloroisocyanurate (NaDCC) solutions containing 0-40% and 0-70% horse serum respectively. The degree of inactivation of NaOCl and of NaDCC solutions by different concentrations of horse serum is expressed in terms of a neutralization coefficient, which demonstrates that NaDCC solutions are less prone to inactivation by serum than are NaOCl solutions, the disparity diverging as serum concentration is increased. In 30% serum an NaDCC solution containing 4000 ppm of available chlorine exhibited similar bactericidal activity to an NaOCl solution containing 17,000 ppm available chlorine. SN - 0195-6701 UR - https://www.unboundmedicine.com/medline/citation/2895139/Comparison_of_sodium_hypochlorite_and_sodium_dichloroisocyanurate_disinfectants:_neutralization_by_serum_ DB - PRIME DP - Unbound Medicine ER -