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Prevalence and pattern of antipsychotic induced movement disorders in a tertiary care teaching hospital in India - a cross-sectional study.
Int J Psychiatry Clin Pract. 2018 Jun; 22(2):101-108.IJ

Abstract

OBJECTIVES

To assess prevalence and pattern of movement disorders among patients taking antipsychotic medications.

METHODS

This cross-sectional, intensive monitoring (patient interview, case record form review and clinical examination) study was conducted in patients taking antipsychotic drugs irrespective of duration for the development of movement disorders. The psychiatrist used Modified Simpson-Angus Scale score (10-item scale), Barnes' rating scale and Abnormal Involuntary Movement Scale to diagnose parkinsonism, akathisia and tardive dyskinesia, respectively. We assessed movement disorders for the preventability and seriousness.

RESULTS

The overall prevalence of antipsychotic induced movement disorders was 5.67% (95% CI: 4.19-7.62). The prevalence of parkinsonism, akathisia and tardive dyskinesia was 5.10% (95% CI: 3.71-6.98), 0.85% (95% CI: 0.39-1.84) and 0.57% (95% CI: 0.22-1.45), respectively. There was a trend of high proportions of movement disorders in extreme of age group, female gender, patients treated with conventional antipsychotics, on poly therapy, patients of epilepsy with psychosis, schizophrenia and bipolar mood disorder. The movement disorder was lowest with quetiapine (2.02%).

CONCLUSIONS

The higher use of atypical antipsychotics had reduced the occurrence of movement disorders in our setup.

Authors+Show Affiliations

a Department of Psychiatry , GMERS General Hospital and Medical College , Vadodara , India.b Department of Pharmacology , GMERS Medical College , Vadodara , India.a Department of Psychiatry , GMERS General Hospital and Medical College , Vadodara , India.b Department of Pharmacology , GMERS Medical College , Vadodara , India.a Department of Psychiatry , GMERS General Hospital and Medical College , Vadodara , India.a Department of Psychiatry , GMERS General Hospital and Medical College , Vadodara , India.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

28952832

Citation

Desai, Nimisha, et al. "Prevalence and Pattern of Antipsychotic Induced Movement Disorders in a Tertiary Care Teaching Hospital in India - a Cross-sectional Study." International Journal of Psychiatry in Clinical Practice, vol. 22, no. 2, 2018, pp. 101-108.
Desai N, Patel PB, Shah S, et al. Prevalence and pattern of antipsychotic induced movement disorders in a tertiary care teaching hospital in India - a cross-sectional study. Int J Psychiatry Clin Pract. 2018;22(2):101-108.
Desai, N., Patel, P. B., Shah, S., Patel, T. K., Shah, S. N., & Vatsala, E. (2018). Prevalence and pattern of antipsychotic induced movement disorders in a tertiary care teaching hospital in India - a cross-sectional study. International Journal of Psychiatry in Clinical Practice, 22(2), 101-108. https://doi.org/10.1080/13651501.2017.1381268
Desai N, et al. Prevalence and Pattern of Antipsychotic Induced Movement Disorders in a Tertiary Care Teaching Hospital in India - a Cross-sectional Study. Int J Psychiatry Clin Pract. 2018;22(2):101-108. PubMed PMID: 28952832.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence and pattern of antipsychotic induced movement disorders in a tertiary care teaching hospital in India - a cross-sectional study. AU - Desai,Nimisha, AU - Patel,Parvati B, AU - Shah,Sandip, AU - Patel,Tejas K, AU - Shah,Saurabh N, AU - Vatsala,Ela, Y1 - 2017/09/27/ PY - 2017/9/28/pubmed PY - 2018/8/21/medline PY - 2017/9/28/entrez KW - Movement disorders KW - antipsychotic agents KW - prevalence SP - 101 EP - 108 JF - International journal of psychiatry in clinical practice JO - Int J Psychiatry Clin Pract VL - 22 IS - 2 N2 - OBJECTIVES: To assess prevalence and pattern of movement disorders among patients taking antipsychotic medications. METHODS: This cross-sectional, intensive monitoring (patient interview, case record form review and clinical examination) study was conducted in patients taking antipsychotic drugs irrespective of duration for the development of movement disorders. The psychiatrist used Modified Simpson-Angus Scale score (10-item scale), Barnes' rating scale and Abnormal Involuntary Movement Scale to diagnose parkinsonism, akathisia and tardive dyskinesia, respectively. We assessed movement disorders for the preventability and seriousness. RESULTS: The overall prevalence of antipsychotic induced movement disorders was 5.67% (95% CI: 4.19-7.62). The prevalence of parkinsonism, akathisia and tardive dyskinesia was 5.10% (95% CI: 3.71-6.98), 0.85% (95% CI: 0.39-1.84) and 0.57% (95% CI: 0.22-1.45), respectively. There was a trend of high proportions of movement disorders in extreme of age group, female gender, patients treated with conventional antipsychotics, on poly therapy, patients of epilepsy with psychosis, schizophrenia and bipolar mood disorder. The movement disorder was lowest with quetiapine (2.02%). CONCLUSIONS: The higher use of atypical antipsychotics had reduced the occurrence of movement disorders in our setup. SN - 1471-1788 UR - https://www.unboundmedicine.com/medline/citation/28952832/Prevalence_and_pattern_of_antipsychotic_induced_movement_disorders_in_a_tertiary_care_teaching_hospital_in_India___a_cross_sectional_study_ L2 - https://www.tandfonline.com/doi/full/10.1080/13651501.2017.1381268 DB - PRIME DP - Unbound Medicine ER -