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[Pyopneumothorax in rheumatoid arthritis].
Rev Mal Respir. 2017 Nov; 34(9):1011-1015.RM

Abstract

INTRODUCTION

Rheumatoid arthritis (RA) is a chronic inflammatory disease affecting the joints but which frequently includes extra articular effects, including pulmonary nodules, which grow faster under immunosuppressive treatment.

CASE REPORT

A 74 years old man, with mild asbestosis, underwent treatment with methotrexate then leflunomide (LEF) for seropositive RA. In February 2014, during monitoring of his asbestosis, chest CT scan showed the appearance of thick-walled cavitating lung nodules, with a central and sub pleural distribution. The patient was asymptomatic. Bronchoalveolar lavage excluded infection and tumor. LEF was stopped but in May 2014, the patient was admitted with respiratory infection and a pyopneumothorax which required surgical management. The postoperative course was complicated with a persistent pneumothorax.

CONCLUSIONS

We describe a case of RA complicated by a pyopneumothorax after treatment with LEF. The risk of this complication could be reduced by regular chest imaging.

Authors+Show Affiliations

Service de pneumologie, clinique Teissier, 119, avenue Desandrouins, 59300 Valenciennes, France. Electronic address: benhuret@hotmail.com.Service de pneumologie, hôpital Victor-Provo, 17, boulevard Lacordaire, 59100 Roubaix, France.Service de chirurgie thoracique, hôpital Jean-Bernard, avenue Desandrouins, 59300 Valenciennes, France.Service de rhumatologie, hôpital Jean-Bernard, avenue Desandrouins, 59300 Valenciennes, France.Service de pneumologie, clinique Teissier, 119, avenue Desandrouins, 59300 Valenciennes, France.

Pub Type(s)

Case Reports
Journal Article

Language

fre

PubMed ID

29033202

Citation

Huret, B, et al. "[Pyopneumothorax in Rheumatoid Arthritis]." Revue Des Maladies Respiratoires, vol. 34, no. 9, 2017, pp. 1011-1015.
Huret B, Boulanger S, Benhamed L, et al. [Pyopneumothorax in rheumatoid arthritis]. Rev Mal Respir. 2017;34(9):1011-1015.
Huret, B., Boulanger, S., Benhamed, L., Deprez, X., & Caparros, D. (2017). [Pyopneumothorax in rheumatoid arthritis]. Revue Des Maladies Respiratoires, 34(9), 1011-1015. https://doi.org/10.1016/j.rmr.2016.11.005
Huret B, et al. [Pyopneumothorax in Rheumatoid Arthritis]. Rev Mal Respir. 2017;34(9):1011-1015. PubMed PMID: 29033202.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Pyopneumothorax in rheumatoid arthritis]. AU - Huret,B, AU - Boulanger,S, AU - Benhamed,L, AU - Deprez,X, AU - Caparros,D, Y1 - 2017/10/13/ PY - 2016/03/20/received PY - 2016/11/12/accepted PY - 2017/10/17/pubmed PY - 2018/10/26/medline PY - 2017/10/17/entrez KW - Leflunomide KW - Lung nodules KW - Léflunomide KW - Nodules pulmonaires KW - Pneumothorax KW - Polyarthrite rhumatoïde KW - Pyopneumothorax KW - Rheumatoid arthritis SP - 1011 EP - 1015 JF - Revue des maladies respiratoires JO - Rev Mal Respir VL - 34 IS - 9 N2 - INTRODUCTION: Rheumatoid arthritis (RA) is a chronic inflammatory disease affecting the joints but which frequently includes extra articular effects, including pulmonary nodules, which grow faster under immunosuppressive treatment. CASE REPORT: A 74 years old man, with mild asbestosis, underwent treatment with methotrexate then leflunomide (LEF) for seropositive RA. In February 2014, during monitoring of his asbestosis, chest CT scan showed the appearance of thick-walled cavitating lung nodules, with a central and sub pleural distribution. The patient was asymptomatic. Bronchoalveolar lavage excluded infection and tumor. LEF was stopped but in May 2014, the patient was admitted with respiratory infection and a pyopneumothorax which required surgical management. The postoperative course was complicated with a persistent pneumothorax. CONCLUSIONS: We describe a case of RA complicated by a pyopneumothorax after treatment with LEF. The risk of this complication could be reduced by regular chest imaging. SN - 1776-2588 UR - https://www.unboundmedicine.com/medline/citation/29033202/[Pyopneumothorax_in_rheumatoid_arthritis] L2 - https://linkinghub.elsevier.com/retrieve/pii/S0761-8425(17)30217-6 DB - PRIME DP - Unbound Medicine ER -