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Hemocoagulase might not control but worsen gastrointestinal bleeding in an elderly patient with type II respiratory failure.

Abstract

Hemocoagulase has been successfully used for the management of bleeding in patients undergoing surgery. Local spray of hemocoagulase during endoscopic therapy may be effective for the management of gastrointestinal bleeding. In China, intravenous infusion of hemocoagulase is given by some physicians for the treatment of gastrointestinal bleeding. However, the potential adverse events secondary to hemocoagulase, such as hypofibrinogenemia, are poorly recognized. In this paper, we reported an elderly patient with type II respiratory failure in whom hemocoagulase might induce hypofibrinogenemia and further worsen gastrointestinal bleeding. We highlighted that fibrinogen levels should be cautiously monitored in patients receiving hemocoagulase.

Authors+Show Affiliations

Department of Gastroenterology, General Hospital of Shenyang Military Area, Shenyang 110840, China.Department of Hematology, General Hospital of Shenyang Military Area, Shenyang 110840, China.Department of Transfusion, General Hospital of Shenyang Military Area, Shenyang 110840, China.Institute of Hematology, Catholic University, Rome, Italy.Department of Gastroenterology, General Hospital of Shenyang Military Area, Shenyang 110840, China.Department of Gastroenterology, General Hospital of Shenyang Military Area, Shenyang 110840, China.Department of Respiratory Medicine, General Hospital of Shenyang Military Area, Shenyang 110840, China.Department of Gastroenterology, General Hospital of Shenyang Military Area, Shenyang 110840, China.Department of Gastroenterology, General Hospital of Shenyang Military Area, Shenyang 110840, China.Department of Gastroenterology, General Hospital of Shenyang Military Area, Shenyang 110840, China.Department of Pharmacology, General Hospital of Shenyang Military Area, Shenyang 110840, China.Department of Gastroenterology, General Hospital of Shenyang Military Area, Shenyang 110840, China.

Pub Type(s)

Case Reports

Language

eng

PubMed ID

29034344

Citation

Qi, Xingshun, et al. "Hemocoagulase Might Not Control but Worsen Gastrointestinal Bleeding in an Elderly Patient With Type II Respiratory Failure." Translational Gastroenterology and Hepatology, vol. 2, 2017, p. 71.
Qi X, Wang J, Yu X, et al. Hemocoagulase might not control but worsen gastrointestinal bleeding in an elderly patient with type II respiratory failure. Transl Gastroenterol Hepatol. 2017;2:71.
Qi, X., Wang, J., Yu, X., De Stefano, V., Li, H., Wu, C., Zeng, Q., Zhang, Y., Ren, L., Lin, H., Deng, J., & Guo, X. (2017). Hemocoagulase might not control but worsen gastrointestinal bleeding in an elderly patient with type II respiratory failure. Translational Gastroenterology and Hepatology, 2, 71. https://doi.org/10.21037/tgh.2017.08.08
Qi X, et al. Hemocoagulase Might Not Control but Worsen Gastrointestinal Bleeding in an Elderly Patient With Type II Respiratory Failure. Transl Gastroenterol Hepatol. 2017;2:71. PubMed PMID: 29034344.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hemocoagulase might not control but worsen gastrointestinal bleeding in an elderly patient with type II respiratory failure. AU - Qi,Xingshun, AU - Wang,Jigang, AU - Yu,Xiaonan, AU - De Stefano,Valerio, AU - Li,Hongyu, AU - Wu,Chunyan, AU - Zeng,Qingwei, AU - Zhang,Yongguo, AU - Ren,Linan, AU - Lin,Hao, AU - Deng,Jiao, AU - Guo,Xiaozhong, Y1 - 2017/09/12/ PY - 2017/08/13/received PY - 2017/08/22/accepted PY - 2017/10/17/entrez PY - 2017/10/17/pubmed PY - 2017/10/17/medline KW - Hemocoagulase KW - endoscopy KW - fibrinogen KW - gastrointestinal bleeding KW - transfusion SP - 71 EP - 71 JF - Translational gastroenterology and hepatology JO - Transl Gastroenterol Hepatol VL - 2 N2 - Hemocoagulase has been successfully used for the management of bleeding in patients undergoing surgery. Local spray of hemocoagulase during endoscopic therapy may be effective for the management of gastrointestinal bleeding. In China, intravenous infusion of hemocoagulase is given by some physicians for the treatment of gastrointestinal bleeding. However, the potential adverse events secondary to hemocoagulase, such as hypofibrinogenemia, are poorly recognized. In this paper, we reported an elderly patient with type II respiratory failure in whom hemocoagulase might induce hypofibrinogenemia and further worsen gastrointestinal bleeding. We highlighted that fibrinogen levels should be cautiously monitored in patients receiving hemocoagulase. SN - 2415-1289 UR - https://www.unboundmedicine.com/medline/citation/29034344/Hemocoagulase_might_not_control_but_worsen_gastrointestinal_bleeding_in_an_elderly_patient_with_type_II_respiratory_failure_ L2 - https://doi.org/10.21037/tgh.2017.08.08 DB - PRIME DP - Unbound Medicine ER -
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