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Methotrexate treatment in a case of juvenile pityriasis rubra pilaris.
Pediatr Dermatol. 2018 Jan; 35(1):e62-e63.PD

Abstract

An 8-year-old boy who was initially diagnosed with plaque psoriasis failed management with topical therapies and skin biopsy confirmed the suspected diagnosis of juvenile pityriasis rubra pilaris (PRP). Pityriasis rubra pilaris is a rare inflammatory disorder of the skin characterized by follicular keratotic papules coalescing into plaques, along with palmoplantar keratoderma. Treatment modalities include topical and systemic therapies, although previous studies have not shown much benefit with methotrexate in children. We present a case in which methotrexate led to significant improvement of the skin findings in a child with type IV juvenile pityriasis rubra pilaris.

Authors+Show Affiliations

Hennepin County Medical Center, Minneapolis, MN, USA.Department of Pediatric Dermatology, University of Minnesota, Minneapolis, MN, USA.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

29044698

Citation

Boyd, Anne H., and Ingrid C. Polcari. "Methotrexate Treatment in a Case of Juvenile Pityriasis Rubra Pilaris." Pediatric Dermatology, vol. 35, no. 1, 2018, pp. e62-e63.
Boyd AH, Polcari IC. Methotrexate treatment in a case of juvenile pityriasis rubra pilaris. Pediatr Dermatol. 2018;35(1):e62-e63.
Boyd, A. H., & Polcari, I. C. (2018). Methotrexate treatment in a case of juvenile pityriasis rubra pilaris. Pediatric Dermatology, 35(1), e62-e63. https://doi.org/10.1111/pde.13326
Boyd AH, Polcari IC. Methotrexate Treatment in a Case of Juvenile Pityriasis Rubra Pilaris. Pediatr Dermatol. 2018;35(1):e62-e63. PubMed PMID: 29044698.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Methotrexate treatment in a case of juvenile pityriasis rubra pilaris. AU - Boyd,Anne H, AU - Polcari,Ingrid C, Y1 - 2017/10/17/ PY - 2017/10/19/pubmed PY - 2018/6/22/medline PY - 2017/10/19/entrez KW - methotrexate KW - pityriasis rubra pilaris KW - psoriasis SP - e62 EP - e63 JF - Pediatric dermatology JO - Pediatr Dermatol VL - 35 IS - 1 N2 - An 8-year-old boy who was initially diagnosed with plaque psoriasis failed management with topical therapies and skin biopsy confirmed the suspected diagnosis of juvenile pityriasis rubra pilaris (PRP). Pityriasis rubra pilaris is a rare inflammatory disorder of the skin characterized by follicular keratotic papules coalescing into plaques, along with palmoplantar keratoderma. Treatment modalities include topical and systemic therapies, although previous studies have not shown much benefit with methotrexate in children. We present a case in which methotrexate led to significant improvement of the skin findings in a child with type IV juvenile pityriasis rubra pilaris. SN - 1525-1470 UR - https://www.unboundmedicine.com/medline/citation/29044698/Methotrexate_treatment_in_a_case_of_juvenile_pityriasis_rubra_pilaris_ DB - PRIME DP - Unbound Medicine ER -
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