Tags

Type your tag names separated by a space and hit enter

Update: Interim Guidance for the Diagnosis, Evaluation, and Management of Infants with Possible Congenital Zika Virus Infection - United States, October 2017.
MMWR Morb Mortal Wkly Rep 2017; 66(41):1089-1099MM

Abstract

CDC has updated its interim guidance for U.S. health care providers caring for infants with possible congenital Zika virus infection (1) in response to recently published updated guidance for health care providers caring for pregnant women with possible Zika virus exposure (2), unknown sensitivity and specificity of currently available diagnostic tests for congenital Zika virus infection, and recognition of additional clinical findings associated with congenital Zika virus infection. All infants born to mothers with possible Zika virus exposure* during pregnancy should receive a standard evaluation at birth and at each subsequent well-child visit including a comprehensive physical examination, age-appropriate vision screening and developmental monitoring and screening using validated tools (3-5), and newborn hearing screen at birth, preferably using auditory brainstem response (ABR) methodology (6). Specific guidance for laboratory testing and clinical evaluation are provided for three clinical scenarios in the setting of possible maternal Zika virus exposure: 1) infants with clinical findings consistent with congenital Zika syndrome regardless of maternal testing results, 2) infants without clinical findings consistent with congenital Zika syndrome who were born to mothers with laboratory evidence of possible Zika virus infection,† and 3) infants without clinical findings consistent with congenital Zika syndrome who were born to mothers without laboratory evidence of possible Zika virus infection. Infants in the first two scenarios should receive further testing and evaluation for Zika virus, whereas for the third group, further testing and clinical evaluation for Zika virus are not recommended. Health care providers should remain alert for abnormal findings (e.g., postnatal-onset microcephaly and eye abnormalities without microcephaly) in infants with possible congenital Zika virus exposure without apparent abnormalities at birth.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29049277

Citation

Adebanjo, Tolulope, et al. "Update: Interim Guidance for the Diagnosis, Evaluation, and Management of Infants With Possible Congenital Zika Virus Infection - United States, October 2017." MMWR. Morbidity and Mortality Weekly Report, vol. 66, no. 41, 2017, pp. 1089-1099.
Adebanjo T, Godfred-Cato S, Viens L, et al. Update: Interim Guidance for the Diagnosis, Evaluation, and Management of Infants with Possible Congenital Zika Virus Infection - United States, October 2017. MMWR Morb Mortal Wkly Rep. 2017;66(41):1089-1099.
Adebanjo, T., Godfred-Cato, S., Viens, L., Fischer, M., Staples, J. E., Kuhnert-Tallman, W., ... Moore, C. A. (2017). Update: Interim Guidance for the Diagnosis, Evaluation, and Management of Infants with Possible Congenital Zika Virus Infection - United States, October 2017. MMWR. Morbidity and Mortality Weekly Report, 66(41), pp. 1089-1099. doi:10.15585/mmwr.mm6641a1.
Adebanjo T, et al. Update: Interim Guidance for the Diagnosis, Evaluation, and Management of Infants With Possible Congenital Zika Virus Infection - United States, October 2017. MMWR Morb Mortal Wkly Rep. 2017 Oct 20;66(41):1089-1099. PubMed PMID: 29049277.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Update: Interim Guidance for the Diagnosis, Evaluation, and Management of Infants with Possible Congenital Zika Virus Infection - United States, October 2017. AU - Adebanjo,Tolulope, AU - Godfred-Cato,Shana, AU - Viens,Laura, AU - Fischer,Marc, AU - Staples,J Erin, AU - Kuhnert-Tallman,Wendi, AU - Walke,Henry, AU - Oduyebo,Titilope, AU - Polen,Kara, AU - Peacock,Georgina, AU - Meaney-Delman,Dana, AU - Honein,Margaret A, AU - Rasmussen,Sonja A, AU - Moore,Cynthia A, AU - ,, Y1 - 2017/10/20/ PY - 2017/10/20/entrez PY - 2017/10/20/pubmed PY - 2017/10/24/medline SP - 1089 EP - 1099 JF - MMWR. Morbidity and mortality weekly report JO - MMWR Morb. Mortal. Wkly. Rep. VL - 66 IS - 41 N2 - CDC has updated its interim guidance for U.S. health care providers caring for infants with possible congenital Zika virus infection (1) in response to recently published updated guidance for health care providers caring for pregnant women with possible Zika virus exposure (2), unknown sensitivity and specificity of currently available diagnostic tests for congenital Zika virus infection, and recognition of additional clinical findings associated with congenital Zika virus infection. All infants born to mothers with possible Zika virus exposure* during pregnancy should receive a standard evaluation at birth and at each subsequent well-child visit including a comprehensive physical examination, age-appropriate vision screening and developmental monitoring and screening using validated tools (3-5), and newborn hearing screen at birth, preferably using auditory brainstem response (ABR) methodology (6). Specific guidance for laboratory testing and clinical evaluation are provided for three clinical scenarios in the setting of possible maternal Zika virus exposure: 1) infants with clinical findings consistent with congenital Zika syndrome regardless of maternal testing results, 2) infants without clinical findings consistent with congenital Zika syndrome who were born to mothers with laboratory evidence of possible Zika virus infection,† and 3) infants without clinical findings consistent with congenital Zika syndrome who were born to mothers without laboratory evidence of possible Zika virus infection. Infants in the first two scenarios should receive further testing and evaluation for Zika virus, whereas for the third group, further testing and clinical evaluation for Zika virus are not recommended. Health care providers should remain alert for abnormal findings (e.g., postnatal-onset microcephaly and eye abnormalities without microcephaly) in infants with possible congenital Zika virus exposure without apparent abnormalities at birth. SN - 1545-861X UR - https://www.unboundmedicine.com/medline/citation/29049277/Update:_Interim_Guidance_for_the_Diagnosis_Evaluation_and_Management_of_Infants_with_Possible_Congenital_Zika_Virus_Infection___United_States_October_2017_ L2 - https://dx.doi.org/10.15585/mmwr.mm6641a1 DB - PRIME DP - Unbound Medicine ER -