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[Continuous intrathecal opiate therapy with a portable drug pump in cancer pain].
Anasth Intensivther Notfallmed. 1988 Oct; 23(5):271-5.AI

Abstract

Terminal cancer patients report substantial pain frequently. Pain control can be achieved in many patients with conventional methods and analgesics. However, significant numbers of patients remain in pain. For these patients, continuous intrathecal narcotics delivered by an external portable pump via a subcutaneous port, offer substantially improved pain control with minimal risk of serious systemic complications. Duration of treatment in our 40 cancer patients lasted up to 11 month. Continuous intrathecal morphine or fentanyl relieved pain till death due to cancer. Supraspinal side effects of opioids were only seen during the first week of intrathecal narcotic treatment. No serious complications like meningitis or other infections were observed. Postmortem examination also could not detect changes of the cord or signs of arachnoiditis due to intrathecal narcotics or the implanted catheter. We conclude, that continuous intrathecal narcotic infusion by means of small portable pump is a very efficient method to control terminal cancer pain and enables treatment on an outpatient basis until death.

Authors+Show Affiliations

Institut für Anaesthesie, Universitätskliniken des Saarlandes Homburg/Saar.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

ger

PubMed ID

2907271

Citation

Motsch, J, et al. "[Continuous Intrathecal Opiate Therapy With a Portable Drug Pump in Cancer Pain]." Anasthesie, Intensivtherapie, Notfallmedizin, vol. 23, no. 5, 1988, pp. 271-5.
Motsch J, Bleser W, Ismaily AJ, et al. [Continuous intrathecal opiate therapy with a portable drug pump in cancer pain]. Anasth Intensivther Notfallmed. 1988;23(5):271-5.
Motsch, J., Bleser, W., Ismaily, A. J., & Distler, L. (1988). [Continuous intrathecal opiate therapy with a portable drug pump in cancer pain]. Anasthesie, Intensivtherapie, Notfallmedizin, 23(5), 271-5.
Motsch J, et al. [Continuous Intrathecal Opiate Therapy With a Portable Drug Pump in Cancer Pain]. Anasth Intensivther Notfallmed. 1988;23(5):271-5. PubMed PMID: 2907271.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Continuous intrathecal opiate therapy with a portable drug pump in cancer pain]. AU - Motsch,J, AU - Bleser,W, AU - Ismaily,A J, AU - Distler,L, PY - 1988/10/1/pubmed PY - 1988/10/1/medline PY - 1988/10/1/entrez SP - 271 EP - 5 JF - Anasthesie, Intensivtherapie, Notfallmedizin JO - Anasth Intensivther Notfallmed VL - 23 IS - 5 N2 - Terminal cancer patients report substantial pain frequently. Pain control can be achieved in many patients with conventional methods and analgesics. However, significant numbers of patients remain in pain. For these patients, continuous intrathecal narcotics delivered by an external portable pump via a subcutaneous port, offer substantially improved pain control with minimal risk of serious systemic complications. Duration of treatment in our 40 cancer patients lasted up to 11 month. Continuous intrathecal morphine or fentanyl relieved pain till death due to cancer. Supraspinal side effects of opioids were only seen during the first week of intrathecal narcotic treatment. No serious complications like meningitis or other infections were observed. Postmortem examination also could not detect changes of the cord or signs of arachnoiditis due to intrathecal narcotics or the implanted catheter. We conclude, that continuous intrathecal narcotic infusion by means of small portable pump is a very efficient method to control terminal cancer pain and enables treatment on an outpatient basis until death. SN - 0174-1837 UR - https://www.unboundmedicine.com/medline/citation/2907271/[Continuous_intrathecal_opiate_therapy_with_a_portable_drug_pump_in_cancer_pain]_ DB - PRIME DP - Unbound Medicine ER -