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[CRISPR-Cas9 mediated genome editing in Caenorhabditis elegans].
Sheng Wu Gong Cheng Xue Bao. 2017 Oct 25; 33(10):1693-1699.SW

Abstract

The development of genome editing techniques based on CRISPR (Clustered regularly interspaced short palindromic repeats)-Cas9 system has revolutionized biomedical researches. It can be utilized to edit genome sequence in almost any organisms including Caenorhabditis elegans, one of the most convenient and classic genetic model animals. The application of CRISPR-Cas9 mediated genome editing in C. elegans promotes the functional analysis of gene and proteins under many physiological conditions. In this mini-review, we summarized the development of CRISPR-Cas9-based genome editing in C. elegans.

Authors+Show Affiliations

School of Medicine, Zhejiang University, Hangzhou 310058, Zhejiang, China.School of Medicine, Zhejiang University, Hangzhou 310058, Zhejiang, China.School of Medicine, Zhejiang University, Hangzhou 310058, Zhejiang, China.

Pub Type(s)

Journal Article
Review

Language

chi

PubMed ID

29082717

Citation

Meng, Xi'nan, et al. "[CRISPR-Cas9 Mediated Genome Editing in Caenorhabditis Elegans]." Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology, vol. 33, no. 10, 2017, pp. 1693-1699.
Meng X, Zhou H, Xu S. [CRISPR-Cas9 mediated genome editing in Caenorhabditis elegans]. Sheng Wu Gong Cheng Xue Bao. 2017;33(10):1693-1699.
Meng, X., Zhou, H., & Xu, S. (2017). [CRISPR-Cas9 mediated genome editing in Caenorhabditis elegans]. Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology, 33(10), 1693-1699. https://doi.org/10.13345/j.cjb.170177
Meng X, Zhou H, Xu S. [CRISPR-Cas9 Mediated Genome Editing in Caenorhabditis Elegans]. Sheng Wu Gong Cheng Xue Bao. 2017 Oct 25;33(10):1693-1699. PubMed PMID: 29082717.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [CRISPR-Cas9 mediated genome editing in Caenorhabditis elegans]. AU - Meng,Xi'nan, AU - Zhou,Hengda, AU - Xu,Suhong, PY - 2017/10/31/entrez PY - 2017/10/31/pubmed PY - 2018/5/1/medline KW - CRISPR-Cas9 KW - NHEJ KW - genetic screening KW - genome editing KW - homology recombination KW - tissue specific SP - 1693 EP - 1699 JF - Sheng wu gong cheng xue bao = Chinese journal of biotechnology JO - Sheng Wu Gong Cheng Xue Bao VL - 33 IS - 10 N2 - The development of genome editing techniques based on CRISPR (Clustered regularly interspaced short palindromic repeats)-Cas9 system has revolutionized biomedical researches. It can be utilized to edit genome sequence in almost any organisms including Caenorhabditis elegans, one of the most convenient and classic genetic model animals. The application of CRISPR-Cas9 mediated genome editing in C. elegans promotes the functional analysis of gene and proteins under many physiological conditions. In this mini-review, we summarized the development of CRISPR-Cas9-based genome editing in C. elegans. SN - 1000-3061 UR - https://www.unboundmedicine.com/medline/citation/29082717/[CRISPR_Cas9_mediated_genome_editing_in_Caenorhabditis_elegans]_ L2 - https://doi.org/10.13345/j.cjb.170177 DB - PRIME DP - Unbound Medicine ER -