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Oligoantigenic diet treatment of children with epilepsy and migraine.
J Pediatr. 1989 Jan; 114(1):51-8.JPed

Abstract

We studied the role of oligoantigenic diets in 63 children with epilepsy; 45 children had epilepsy with migraine, hyperkinetic behavior, or both, and 18 had epilepsy alone. Of the 45 children who had epilepsy with recurrent headaches, abdominal symptoms, or hyperkinetic behavior, 25 ceased to have seizures and 11 had fewer seizures during diet therapy. Headaches, abdominal pains, and hyperkinetic behavior ceased in all those whose seizures ceased, and in some of those whose seizures did not cease. Foods provoking symptoms were identified by systematic reintroduction of foods, one by one; symptoms recurred with 42 foods, and seizures recurred with 31; most children reacted to several foods. Of 24 children with generalized epilepsy, 18 recovered or improved (including 4 of 7 with myoclonic seizures and all with petit mal), as did 18 of 21 children with partial epilepsy. In double-blind, placebo-controlled provocation studies, symptoms recurred in 15 of 16 children, including seizures in eight; none recurred when placebo was given. Eighteen other children, who had epilepsy alone, were similarly treated with an oligoantigenic diet; none improved.

Authors+Show Affiliations

Department of Neurology, Hospital for Sick Children, London.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Controlled Clinical Trial
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

2909707

Citation

Egger, J, et al. "Oligoantigenic Diet Treatment of Children With Epilepsy and Migraine." The Journal of Pediatrics, vol. 114, no. 1, 1989, pp. 51-8.
Egger J, Carter CM, Soothill JF, et al. Oligoantigenic diet treatment of children with epilepsy and migraine. J Pediatr. 1989;114(1):51-8.
Egger, J., Carter, C. M., Soothill, J. F., & Wilson, J. (1989). Oligoantigenic diet treatment of children with epilepsy and migraine. The Journal of Pediatrics, 114(1), 51-8.
Egger J, et al. Oligoantigenic Diet Treatment of Children With Epilepsy and Migraine. J Pediatr. 1989;114(1):51-8. PubMed PMID: 2909707.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Oligoantigenic diet treatment of children with epilepsy and migraine. AU - Egger,J, AU - Carter,C M, AU - Soothill,J F, AU - Wilson,J, PY - 1989/1/1/pubmed PY - 1989/1/1/medline PY - 1989/1/1/entrez SP - 51 EP - 8 JF - The Journal of pediatrics JO - J. Pediatr. VL - 114 IS - 1 N2 - We studied the role of oligoantigenic diets in 63 children with epilepsy; 45 children had epilepsy with migraine, hyperkinetic behavior, or both, and 18 had epilepsy alone. Of the 45 children who had epilepsy with recurrent headaches, abdominal symptoms, or hyperkinetic behavior, 25 ceased to have seizures and 11 had fewer seizures during diet therapy. Headaches, abdominal pains, and hyperkinetic behavior ceased in all those whose seizures ceased, and in some of those whose seizures did not cease. Foods provoking symptoms were identified by systematic reintroduction of foods, one by one; symptoms recurred with 42 foods, and seizures recurred with 31; most children reacted to several foods. Of 24 children with generalized epilepsy, 18 recovered or improved (including 4 of 7 with myoclonic seizures and all with petit mal), as did 18 of 21 children with partial epilepsy. In double-blind, placebo-controlled provocation studies, symptoms recurred in 15 of 16 children, including seizures in eight; none recurred when placebo was given. Eighteen other children, who had epilepsy alone, were similarly treated with an oligoantigenic diet; none improved. SN - 0022-3476 UR - https://www.unboundmedicine.com/medline/citation/2909707/Oligoantigenic_diet_treatment_of_children_with_epilepsy_and_migraine_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0022-3476(89)80600-6 DB - PRIME DP - Unbound Medicine ER -