Citation
Tamana, Sukhpreet K., et al. "Parent-Reported Symptoms of Sleep-Disordered Breathing Are Associated With Increased Behavioral Problems at 2 Years of Age: the Canadian Healthy Infant Longitudinal Development Birth Cohort Study." Sleep, vol. 41, no. 1, 2018.
Tamana SK, Smithson L, Lau A, et al. Parent-Reported Symptoms of Sleep-Disordered Breathing Are Associated With Increased Behavioral Problems at 2 Years of Age: The Canadian Healthy Infant Longitudinal Development Birth Cohort Study. Sleep. 2018;41(1).
Tamana, S. K., Smithson, L., Lau, A., Mariasine, J., Young, R., Chikuma, J., Lefebvre, D. L., Subbarao, P., Becker, A. B., Turvey, S. E., Sears, M. R., Pei, J., & Mandhane, P. J. (2018). Parent-Reported Symptoms of Sleep-Disordered Breathing Are Associated With Increased Behavioral Problems at 2 Years of Age: The Canadian Healthy Infant Longitudinal Development Birth Cohort Study. Sleep, 41(1). https://doi.org/10.1093/sleep/zsx177
Tamana SK, et al. Parent-Reported Symptoms of Sleep-Disordered Breathing Are Associated With Increased Behavioral Problems at 2 Years of Age: the Canadian Healthy Infant Longitudinal Development Birth Cohort Study. Sleep. 2018 01 1;41(1) PubMed PMID: 29099980.
TY - JOUR
T1 - Parent-Reported Symptoms of Sleep-Disordered Breathing Are Associated With Increased Behavioral Problems at 2 Years of Age: The Canadian Healthy Infant Longitudinal Development Birth Cohort Study.
AU - Tamana,Sukhpreet K,
AU - Smithson,Lisa,
AU - Lau,Amanda,
AU - Mariasine,Jennifer,
AU - Young,Rochelle,
AU - Chikuma,Joyce,
AU - Lefebvre,Diana L,
AU - Subbarao,Padmaja,
AU - Becker,Allan B,
AU - Turvey,Stuart E,
AU - Sears,Malcolm R,
AU - ,,
AU - Pei,Jacqueline,
AU - Mandhane,Piush J,
PY - 2017/11/4/pubmed
PY - 2019/6/14/medline
PY - 2017/11/4/entrez
KW - behavior
KW - epidemiology
KW - infants
KW - population-based birth cohort
KW - sleep apnea
KW - sleep-disordered breathing
JF - Sleep
JO - Sleep
VL - 41
IS - 1
N2 - Study Objectives: To examine the association between the age of onset and duration of parent-reported symptoms of sleep-disordered breathing (SDB) and behavioral problems at age 2. Methods: Parent-reported SDB symptoms were assessed quarterly between 3 months and 2 years among 583 Canadian Healthy Infant Longitudinal Development Edmonton-site participants. Parent-reported SDB symptoms were clustered into phenotypes using group-based trajectory analysis based on age of onset and duration of symptoms. Home-based polysomnography (PSG) was completed at 1 year. The Child Behavior Checklist preschool-version (Mean T-score 50, standard deviation 10 points) assessed total, externalizing (attention), and internalizing (anxiety, depression) behaviors at 2 years. Results: Four phenotypes were identified: no SDB (64.7%), early-onset SDB (15.7%, peak symptoms at 9 months), late-onset (14.2%, peak symptoms at 18 months), and persistent SDB symptoms (5.3%, peak symptoms from 3 through 24 months). Persistent SDB (9.5 points, 95% CI 1.7, 17.2; p = .02) predicted the greatest magnitude of effect of total behavior problems, compared with children without SDB. Children with early-onset SDB (3.5 points, 95% CI 1.6, 5.4; p ≤ .001) and late-onset SDB (6.1 points 95% CI 4.0, 8.3; p ≤ .001) had increased total behavioral problems than children without SDB to 2 years. Additional analyses showed that the SDB phenotypes' trajectories were important for internalizing but not for externalizing behavior problems. There were no significant associations between home-PSG and parent-reported behavior problems. Conclusions: Findings suggest that the age of onset and duration of parent-reported SDB symptoms prior to age 2 have adverse consequences for overall behavior problems.
SN - 1550-9109
UR - https://www.unboundmedicine.com/medline/citation/29099980/Parent_Reported_Symptoms_of_Sleep_Disordered_Breathing_Are_Associated_With_Increased_Behavioral_Problems_at_2_Years_of_Age:_The_Canadian_Healthy_Infant_Longitudinal_Development_Birth_Cohort_Study_
L2 - https://academic.oup.com/sleep/article-lookup/doi/10.1093/sleep/zsx177
DB - PRIME
DP - Unbound Medicine
ER -