Tags

Type your tag names separated by a space and hit enter

Thai plants with high antioxidant levels, free radical scavenging activity, anti-tyrosinase and anti-collagenase activity.
BMC Complement Altern Med. 2017 Nov 09; 17(1):487.BC

Abstract

BACKGROUND

Ultraviolet radiation from sunlight induces overproduction of reactive oxygen species (ROS) resulting in skin photoaging and hyperpigmentation disorders. Novel whitening and anti-wrinkle compounds from natural products have recently become of increasing interest. The purpose of this study was to find products that reduce ROS in 14 Thai plant extracts.

METHODS

To determine total phenolic and flavonoid content, antioxidant activity, anti-tyrosinase activity and anti-collagenase activity, we compared extracts of 14 Thai plants prepared using different solvents (petroleum ether, dichloromethane and ethanol). Antioxidant activities were determined by DPPH and ABTS assays.

RESULTS

Total phenolic content of the 14 Thai plants extracts was found at the highest levels in ethanol followed by dichloromethane and petroleum ether extracts, respectively, while flavonoid content was normally found in the dichloromethane fraction. Scavenging activity ranged from 7 to 99% scavenging as assessed by DPPH and ABTS assays. The ethanol leaf extract of Ardisia elliptica Thunb. had the highest phenolic content, antioxidant activity and collagenase inhibition, while Cassia alata (L.) Roxb. extract had the richest flavonoid content. Interestingly, three plants extracts, which were the ethanolic fractions of Annona squamosa L., Ardisia elliptica Thunb. and Senna alata (L.) Roxb., had high antioxidant content and activity, and significantly inhibited both tyrosinase and collagenase.

CONCLUSION

Our finding show that the ethanol fractions of Annona squamosa L., Ardisia elliptica Thunb. and Senna alata (L.) Roxb. show promise as potential ingredients for cosmetic products such as anti-wrinkle agents and skin whitening products.

Authors+Show Affiliations

Program in Clinical Biochemistry and Molecular Medicine, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, Thailand.Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, 10330, Thailand. anchalee.c@chula.ac.th.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29121910

Citation

Chatatikun, Moragot, and Anchalee Chiabchalard. "Thai Plants With High Antioxidant Levels, Free Radical Scavenging Activity, Anti-tyrosinase and Anti-collagenase Activity." BMC Complementary and Alternative Medicine, vol. 17, no. 1, 2017, p. 487.
Chatatikun M, Chiabchalard A. Thai plants with high antioxidant levels, free radical scavenging activity, anti-tyrosinase and anti-collagenase activity. BMC Complement Altern Med. 2017;17(1):487.
Chatatikun, M., & Chiabchalard, A. (2017). Thai plants with high antioxidant levels, free radical scavenging activity, anti-tyrosinase and anti-collagenase activity. BMC Complementary and Alternative Medicine, 17(1), 487. https://doi.org/10.1186/s12906-017-1994-7
Chatatikun M, Chiabchalard A. Thai Plants With High Antioxidant Levels, Free Radical Scavenging Activity, Anti-tyrosinase and Anti-collagenase Activity. BMC Complement Altern Med. 2017 Nov 9;17(1):487. PubMed PMID: 29121910.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Thai plants with high antioxidant levels, free radical scavenging activity, anti-tyrosinase and anti-collagenase activity. AU - Chatatikun,Moragot, AU - Chiabchalard,Anchalee, Y1 - 2017/11/09/ PY - 2017/05/30/received PY - 2017/11/01/accepted PY - 2017/11/11/entrez PY - 2017/11/11/pubmed PY - 2017/11/29/medline KW - Anti-collagenase activity KW - Anti-tyrosinase activity KW - Antioxidant content KW - Ardisia elliptica Thunb. KW - Scavenging activity SP - 487 EP - 487 JF - BMC complementary and alternative medicine JO - BMC Complement Altern Med VL - 17 IS - 1 N2 - BACKGROUND: Ultraviolet radiation from sunlight induces overproduction of reactive oxygen species (ROS) resulting in skin photoaging and hyperpigmentation disorders. Novel whitening and anti-wrinkle compounds from natural products have recently become of increasing interest. The purpose of this study was to find products that reduce ROS in 14 Thai plant extracts. METHODS: To determine total phenolic and flavonoid content, antioxidant activity, anti-tyrosinase activity and anti-collagenase activity, we compared extracts of 14 Thai plants prepared using different solvents (petroleum ether, dichloromethane and ethanol). Antioxidant activities were determined by DPPH and ABTS assays. RESULTS: Total phenolic content of the 14 Thai plants extracts was found at the highest levels in ethanol followed by dichloromethane and petroleum ether extracts, respectively, while flavonoid content was normally found in the dichloromethane fraction. Scavenging activity ranged from 7 to 99% scavenging as assessed by DPPH and ABTS assays. The ethanol leaf extract of Ardisia elliptica Thunb. had the highest phenolic content, antioxidant activity and collagenase inhibition, while Cassia alata (L.) Roxb. extract had the richest flavonoid content. Interestingly, three plants extracts, which were the ethanolic fractions of Annona squamosa L., Ardisia elliptica Thunb. and Senna alata (L.) Roxb., had high antioxidant content and activity, and significantly inhibited both tyrosinase and collagenase. CONCLUSION: Our finding show that the ethanol fractions of Annona squamosa L., Ardisia elliptica Thunb. and Senna alata (L.) Roxb. show promise as potential ingredients for cosmetic products such as anti-wrinkle agents and skin whitening products. SN - 1472-6882 UR - https://www.unboundmedicine.com/medline/citation/29121910/Thai_plants_with_high_antioxidant_levels_free_radical_scavenging_activity_anti_tyrosinase_and_anti_collagenase_activity_ L2 - https://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-017-1994-7 DB - PRIME DP - Unbound Medicine ER -