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Polymorphisms of 23 Y-chromosome STR Loci in A Han Population in Jiangsu Province.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2017 Oct 30; 39(5):629-636.ZY

Abstract

Objective To investigate the polymorphisms of 23 Y-STR loci in a Han population in Jiangsu province. Methods Blood samples were collected from 4821 unrelated healthy Han males in Jiangsu province. DNA templates were amplified by PowerPlex Y23 kit,and the amplification products were detected by 3500xL genetic analyzer. Then,we calculated the allele frequencies and gene diversities respectively,as well as the haplotype frequencies and haplotype diversities. Results The gene diversity of these 23 Y-STR loci ranged 0.4099-0.9696. A total of 4781 haplotypes were detected,of which 4743 were found once. The haplotype diversity was 0.99999812. Conclusion The 23 Y-STR loci used in this study are highly polymorphic in Han individuals in Jiangsu province and therefore suitable for population genetic study and forensic individual identification.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Institute of Forensic Science of Public Security Bureau of Changzhou,Changzhou,Jiangsu 213003,China.

Institute of Forensic Science of Public Security Bureau of Changzhou,Changzhou,Jiangsu 213003,China.

Institute of Forensic Science of Public Security Bureau of Changzhou,Changzhou,Jiangsu 213003,China.

Institute of Forensic Science of Public Security Bureau of Changzhou,Changzhou,Jiangsu 213003,China.

Institute of Forensic Science of Public Security Bureau of Changzhou,Changzhou,Jiangsu 213003,China.

Department of Health Biostatistics,College of Public Health,Zhengzhou University,Zhengzhou 450001,China.

MeSH

Asian PeopleChinaChromosomes, Human, YGene FrequencyGenetics, PopulationHaplotypesHumansMaleMicrosatellite RepeatsPolymorphism, Genetic

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29125104

Citation

Ma, Jun, et al. "Polymorphisms of 23 Y-chromosome STR Loci in a Han Population in Jiangsu Province." Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae, vol. 39, no. 5, 2017, pp. 629-636.

Ma J, Zhu AH, Shi JW, et al. Polymorphisms of 23 Y-chromosome STR Loci in A Han Population in Jiangsu Province. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2017;39(5):629-636.

Ma, J., Zhu, A. H., Shi, J. W., Jin, M., Ba, H. J., & Ping, Z. G. (2017). Polymorphisms of 23 Y-chromosome STR Loci in A Han Population in Jiangsu Province. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae, 39(5), 629-636. https://doi.org/10.3881/j.issn.1000-503X.2017.05.006

Ma J, et al. Polymorphisms of 23 Y-chromosome STR Loci in a Han Population in Jiangsu Province. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2017 Oct 30;39(5):629-636. PubMed PMID: 29125104.

* Article titles in AMA citation format should be in sentence-case

TY - JOUR T1 - Polymorphisms of 23 Y-chromosome STR Loci in A Han Population in Jiangsu Province. AU - Ma,Jun, AU - Zhu,Ai-Hua, AU - Shi,Jin-Wei, AU - Jin,Ming, AU - Ba,Hua-Jie, AU - Ping,Zhi-Guang, PY - 2017/11/11/entrez PY - 2017/11/11/pubmed PY - 2019/2/13/medline SP - 629 EP - 636 JF - Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae JO - Zhongguo Yi Xue Ke Xue Yuan Xue Bao VL - 39 IS - 5 N2 - Objective To investigate the polymorphisms of 23 Y-STR loci in a Han population in Jiangsu province. Methods Blood samples were collected from 4821 unrelated healthy Han males in Jiangsu province. DNA templates were amplified by PowerPlex Y23 kit,and the amplification products were detected by 3500xL genetic analyzer. Then,we calculated the allele frequencies and gene diversities respectively,as well as the haplotype frequencies and haplotype diversities. Results The gene diversity of these 23 Y-STR loci ranged 0.4099-0.9696. A total of 4781 haplotypes were detected,of which 4743 were found once. The haplotype diversity was 0.99999812. Conclusion The 23 Y-STR loci used in this study are highly polymorphic in Han individuals in Jiangsu province and therefore suitable for population genetic study and forensic individual identification. SN - 1000-503X UR - https://www.unboundmedicine.com/medline/citation/29125104/Polymorphisms_of_23_Y_chromosome_STR_Loci_in_A_Han_Population_in_Jiangsu_Province_ DB - PRIME DP - Unbound Medicine ER -