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Anticoagulant Effects of Arginine-Containing Peptides of the Glyproline Family (His-Phe-Arg-Trp-Pro-Gly-Pro and Thr-Lys-Pro-Arg-Pro-Gly-Pro) Revealed by Thromboelastography.
Bull Exp Biol Med. 2017 Dec; 164(2):170-172.BE

Abstract

Thromboelastography revealed anticoagulant effects of 3 glyproline oligopeptides (in various concentrations): His-Phe-Arg-Trp-Pro-Gly-Pro, Thr-Lys-Pro-Arg-Pro-Gly-Pro (Selank), and Pro-Gly-Pro. The parameters R, K, MA, S, TMA, and J changed to hypocoagulation direction in comparison to the control. At this, Selank demonstrated the maximal anticoagulation potency.

Authors+Show Affiliations

Department of Human and Animal Physiology, Biological Faculty, M. V. Lomonosov Moscow State University, Moscow, Russia. elinamiss007@mail.ru.Department of Human and Animal Physiology, Biological Faculty, M. V. Lomonosov Moscow State University, Moscow, Russia.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29181670

Citation

Rogozinskaya, E Ya, and M G. Lyapina. "Anticoagulant Effects of Arginine-Containing Peptides of the Glyproline Family (His-Phe-Arg-Trp-Pro-Gly-Pro and Thr-Lys-Pro-Arg-Pro-Gly-Pro) Revealed By Thromboelastography." Bulletin of Experimental Biology and Medicine, vol. 164, no. 2, 2017, pp. 170-172.
Rogozinskaya EY, Lyapina MG. Anticoagulant Effects of Arginine-Containing Peptides of the Glyproline Family (His-Phe-Arg-Trp-Pro-Gly-Pro and Thr-Lys-Pro-Arg-Pro-Gly-Pro) Revealed by Thromboelastography. Bull Exp Biol Med. 2017;164(2):170-172.
Rogozinskaya, E. Y., & Lyapina, M. G. (2017). Anticoagulant Effects of Arginine-Containing Peptides of the Glyproline Family (His-Phe-Arg-Trp-Pro-Gly-Pro and Thr-Lys-Pro-Arg-Pro-Gly-Pro) Revealed by Thromboelastography. Bulletin of Experimental Biology and Medicine, 164(2), 170-172. https://doi.org/10.1007/s10517-017-3950-4
Rogozinskaya EY, Lyapina MG. Anticoagulant Effects of Arginine-Containing Peptides of the Glyproline Family (His-Phe-Arg-Trp-Pro-Gly-Pro and Thr-Lys-Pro-Arg-Pro-Gly-Pro) Revealed By Thromboelastography. Bull Exp Biol Med. 2017;164(2):170-172. PubMed PMID: 29181670.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Anticoagulant Effects of Arginine-Containing Peptides of the Glyproline Family (His-Phe-Arg-Trp-Pro-Gly-Pro and Thr-Lys-Pro-Arg-Pro-Gly-Pro) Revealed by Thromboelastography. AU - Rogozinskaya,E Ya, AU - Lyapina,M G, Y1 - 2017/11/27/ PY - 2017/04/05/received PY - 2017/11/29/pubmed PY - 2018/7/17/medline PY - 2017/11/29/entrez KW - anticoagulation activity KW - regulatory peptides KW - thromboelastography SP - 170 EP - 172 JF - Bulletin of experimental biology and medicine JO - Bull Exp Biol Med VL - 164 IS - 2 N2 - Thromboelastography revealed anticoagulant effects of 3 glyproline oligopeptides (in various concentrations): His-Phe-Arg-Trp-Pro-Gly-Pro, Thr-Lys-Pro-Arg-Pro-Gly-Pro (Selank), and Pro-Gly-Pro. The parameters R, K, MA, S, TMA, and J changed to hypocoagulation direction in comparison to the control. At this, Selank demonstrated the maximal anticoagulation potency. SN - 1573-8221 UR - https://www.unboundmedicine.com/medline/citation/29181670/Anticoagulant_Effects_of_Arginine_Containing_Peptides_of_the_Glyproline_Family__His_Phe_Arg_Trp_Pro_Gly_Pro_and_Thr_Lys_Pro_Arg_Pro_Gly_Pro__Revealed_by_Thromboelastography_ DB - PRIME DP - Unbound Medicine ER -