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Multiple sclerosis, a treatable disease .
Clin Med (Lond) 2017; 17(6):530-536CM

Abstract

This article reviews our current understanding and modern treatment of multiple sclerosis (MS). MS is a disabling condition resulting in devastating social and economic impacts. As MS can affect any part of the central nervous system, the presentation is often diverse; however, there are key features that can be useful in the clinic. We comment on the diagnostic criteria and review the main subtypes of MS, including clinically isolated syndrome, relapsing remitting MS, secondary progressive MS and primary progressive MS. Although the underlying aetiology of MS is still not known, we summarise those with most evidence of association. Finally, we aim to present treatment strategies for managing the acute relapse, disease-modifying therapies and MS symptoms. This review highlights that progressive MS is an area where there is currently a paucity of available disease-modifying treatments and this will be a major focus for future development.

Authors+Show Affiliations

University College London, London, UK anisha.doshi@ucl.ac.uk.University College London, London, UK.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

29196354

Citation

Doshi, Anisha, and Jeremy Chataway. "Multiple Sclerosis, a Treatable Disease ." Clinical Medicine (London, England), vol. 17, no. 6, 2017, pp. 530-536.
Doshi A, Chataway J. Multiple sclerosis, a treatable disease . Clin Med (Lond). 2017;17(6):530-536.
Doshi, A., & Chataway, J. (2017). Multiple sclerosis, a treatable disease . Clinical Medicine (London, England), 17(6), pp. 530-536. doi:10.7861/clinmedicine.17-6-530.
Doshi A, Chataway J. Multiple Sclerosis, a Treatable Disease. Clin Med (Lond). 2017;17(6):530-536. PubMed PMID: 29196354.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Multiple sclerosis, a treatable disease . AU - Doshi,Anisha, AU - Chataway,Jeremy, PY - 2017/12/3/entrez PY - 2017/12/3/pubmed PY - 2018/7/25/medline KW - Diagnostic criteria KW - epidemiology KW - multiple sclerosis KW - progressive multiple sclerosis KW - treatments SP - 530 EP - 536 JF - Clinical medicine (London, England) JO - Clin Med (Lond) VL - 17 IS - 6 N2 - This article reviews our current understanding and modern treatment of multiple sclerosis (MS). MS is a disabling condition resulting in devastating social and economic impacts. As MS can affect any part of the central nervous system, the presentation is often diverse; however, there are key features that can be useful in the clinic. We comment on the diagnostic criteria and review the main subtypes of MS, including clinically isolated syndrome, relapsing remitting MS, secondary progressive MS and primary progressive MS. Although the underlying aetiology of MS is still not known, we summarise those with most evidence of association. Finally, we aim to present treatment strategies for managing the acute relapse, disease-modifying therapies and MS symptoms. This review highlights that progressive MS is an area where there is currently a paucity of available disease-modifying treatments and this will be a major focus for future development. SN - 1473-4893 UR - https://www.unboundmedicine.com/medline/citation/29196354/Multiple_sclerosis_a_treatable_disease__ L2 - http://www.clinmed.rcpjournal.org/cgi/pmidlookup?view=long&pmid=29196354 DB - PRIME DP - Unbound Medicine ER -