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Screening for Chlamydia trachomatis and Neisseria gonorrhoeae infection among asymptomatic men who have sex with men in Bangkok, Thailand.
Int J STD AIDS. 2018 05; 29(6):577-587.IJ

Abstract

We report positivity rates of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infection at each anatomic site among asymptomatic men who have sex with men (MSM). We calculated the number needed to screen (NNS) to detect CT and NG infection at each anatomic site. From 2006 to 2010, we enrolled Thai MSM, age ≥ 18 years into the Bangkok MSM Cohort Study. Participants underwent physical examination and had rectal, urethral, and pharyngeal screening for CT and NG infection using nucleic acid amplification tests (NAATs). Of 1744 enrollees, 1696 (97.2%) had no symptoms of CT and NG infection. The positivity rates of CT and NG infection at any site were 14.3% (rectum, urethra, pharynx) and 6.4% (rectum, urethra), respectively. The NNS to detect rectal CT and rectal NG infections was 10 and 16, respectively (p < 0.05). For urethral infection, the NNS of CT was lower than the NNS of NG (22, 121: p < 0.05). The lowest NNS found for rectal CT infection was in HIV-infected MSM (6, 5-8). Asymptomatic CT and NG infection were common among MSM in Bangkok, Thailand and frequently detected in the rectum. In setting where screening in all specimens using NAAT is not feasible, rectal screening should be a priority.

Authors+Show Affiliations

1 Thailand Ministry of Public Health - U.S. Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand.1 Thailand Ministry of Public Health - U.S. Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand. 2 Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.1 Thailand Ministry of Public Health - U.S. Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand.1 Thailand Ministry of Public Health - U.S. Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand.1 Thailand Ministry of Public Health - U.S. Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand.1 Thailand Ministry of Public Health - U.S. Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand.1 Thailand Ministry of Public Health - U.S. Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand.1 Thailand Ministry of Public Health - U.S. Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand.3 Department of Disease Control, Ministry of Public health, Nonthaburi, Thailand.1 Thailand Ministry of Public Health - U.S. Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand. 2 Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA. 5 Division of Global HIV and TB, Centers for Disease Control and Prevention, Atlanta, GA, USA.1 Thailand Ministry of Public Health - U.S. Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand. 2 Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA. 4 Department of Medicine, Division of Infectious Diseases, Oregon Health and Sciences University, Portland, OR, USA.

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

29198179

Citation

Pattanasin, Sarika, et al. "Screening for Chlamydia Trachomatis and Neisseria Gonorrhoeae Infection Among Asymptomatic Men Who Have Sex With Men in Bangkok, Thailand." International Journal of STD & AIDS, vol. 29, no. 6, 2018, pp. 577-587.
Pattanasin S, Dunne EF, Wasinrapee P, et al. Screening for Chlamydia trachomatis and Neisseria gonorrhoeae infection among asymptomatic men who have sex with men in Bangkok, Thailand. Int J STD AIDS. 2018;29(6):577-587.
Pattanasin, S., Dunne, E. F., Wasinrapee, P., Tongtoyai, J., Chonwattana, W., Sriporn, A., Luechai, P., Mock, P. A., Chitwarakorn, A., Holtz, T. H., & Curlin, M. E. (2018). Screening for Chlamydia trachomatis and Neisseria gonorrhoeae infection among asymptomatic men who have sex with men in Bangkok, Thailand. International Journal of STD & AIDS, 29(6), 577-587. https://doi.org/10.1177/0956462417744904
Pattanasin S, et al. Screening for Chlamydia Trachomatis and Neisseria Gonorrhoeae Infection Among Asymptomatic Men Who Have Sex With Men in Bangkok, Thailand. Int J STD AIDS. 2018;29(6):577-587. PubMed PMID: 29198179.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Screening for Chlamydia trachomatis and Neisseria gonorrhoeae infection among asymptomatic men who have sex with men in Bangkok, Thailand. AU - Pattanasin,Sarika, AU - Dunne,Eileen F, AU - Wasinrapee,Punneeporn, AU - Tongtoyai,Jaray, AU - Chonwattana,Wannee, AU - Sriporn,Anuwat, AU - Luechai,Pikunchai, AU - Mock,Philip A, AU - Chitwarakorn,Anupong, AU - Holtz,Timothy H, AU - Curlin,Marcel E, Y1 - 2017/12/04/ PY - 2017/12/5/pubmed PY - 2019/1/19/medline PY - 2017/12/5/entrez KW - Chlamydia trachomatis KW - Men who have sex with men KW - Neisseria gonorrhoeae KW - screening SP - 577 EP - 587 JF - International journal of STD & AIDS JO - Int J STD AIDS VL - 29 IS - 6 N2 - We report positivity rates of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infection at each anatomic site among asymptomatic men who have sex with men (MSM). We calculated the number needed to screen (NNS) to detect CT and NG infection at each anatomic site. From 2006 to 2010, we enrolled Thai MSM, age ≥ 18 years into the Bangkok MSM Cohort Study. Participants underwent physical examination and had rectal, urethral, and pharyngeal screening for CT and NG infection using nucleic acid amplification tests (NAATs). Of 1744 enrollees, 1696 (97.2%) had no symptoms of CT and NG infection. The positivity rates of CT and NG infection at any site were 14.3% (rectum, urethra, pharynx) and 6.4% (rectum, urethra), respectively. The NNS to detect rectal CT and rectal NG infections was 10 and 16, respectively (p < 0.05). For urethral infection, the NNS of CT was lower than the NNS of NG (22, 121: p < 0.05). The lowest NNS found for rectal CT infection was in HIV-infected MSM (6, 5-8). Asymptomatic CT and NG infection were common among MSM in Bangkok, Thailand and frequently detected in the rectum. In setting where screening in all specimens using NAAT is not feasible, rectal screening should be a priority. SN - 1758-1052 UR - https://www.unboundmedicine.com/medline/citation/29198179/Screening_for_Chlamydia_trachomatis_and_Neisseria_gonorrhoeae_infection_among_asymptomatic_men_who_have_sex_with_men_in_Bangkok_Thailand_ L2 - https://journals.sagepub.com/doi/10.1177/0956462417744904?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -