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Clinical evaluation of efficacy of Alambushadi Ghana Vati and Vaitarana Basti in the management of Amavata with special reference to rheumatoid arthritis.
Ayu. 2016 Apr-Jun; 37(2):105-112.AYU

Abstract

The clinical presentation of Amavata closely mimics with the special variety of rheumatologic disorders called rheumatoid arthritis (RA). The Ayurvedic approach toward the treatment of Amavata is the need of present era as no system is successful in providing the complete cure to this disease. Amavata is a challenging and a burning problem of medical science. Prevalence of RA is approximately 0.8% of the population. Due to wide spectrum of disease, much prevalence in the society, and lack of effective medicine, the disease had been chosen for the study. The aim of the research was to study the efficacy of Alambushadi Ghana Vati and Vaitarana Basti in the management of Amavata (RA). It was a single-center, randomized, open-clinical study. In the present study, 30 clinically diagnosed patients of Amavata were selected and randomly divided into two groups by lottery method. Alambushadi Ghana Vati was given in dose of two tablets (each 500 mg) three times in a day with lukewarm water after meal for 30 days, while Vaitarana Basti on alternate day (15 Basti) had been given simultaneously in the second group along with drug of first group. Statistical analysis was done using InStat GraphPad 3 Software. Wilcoxon matched pairs signed ranks test was used for the analysis of nonparametric data, while paired t-test was used for parametric data analysis and Mann-Whitney test and unpaired t-test were used for intergroup comparison. Statistically highly significant (HS) improvement was found in erythrocyte sedimentation rate, and HS results were found in symptoms of Amavata when the Vaitarana Basti was used along with Alambushadi Ghana Vati. With excellent relief in 20% patients, significant relief in 60% patients, moderate relief in 13.33% patients, whereas mild relief in 6.66% patients. On comparing the effect of two therapies, it can be concluded that Group B (Alambushadi Ghana Vati and Vaitarana Basti) provided better relief than Group A (Alambushadi Ghana Vati) in most of the sign and symptom of the disease at significant level.

Authors+Show Affiliations

Department of Kayachikitsa, National Institute of Ayurveda, Jaipur, Rajasthan, India.Department of Kayachikitsa, National Institute of Ayurveda, Jaipur, Rajasthan, India.Department of Kayachikitsa, National Institute of Ayurveda, Jaipur, Rajasthan, India.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29200748

Citation

Sasane, Prashant, et al. "Clinical Evaluation of Efficacy of Alambushadi Ghana Vati and Vaitarana Basti in the Management of Amavata With Special Reference to Rheumatoid Arthritis." Ayu, vol. 37, no. 2, 2016, pp. 105-112.
Sasane P, Saroj UR, Joshi RK. Clinical evaluation of efficacy of Alambushadi Ghana Vati and Vaitarana Basti in the management of Amavata with special reference to rheumatoid arthritis. Ayu. 2016;37(2):105-112.
Sasane, P., Saroj, U. R., & Joshi, R. K. (2016). Clinical evaluation of efficacy of Alambushadi Ghana Vati and Vaitarana Basti in the management of Amavata with special reference to rheumatoid arthritis. Ayu, 37(2), 105-112. https://doi.org/10.4103/ayu.AYU_91_15
Sasane P, Saroj UR, Joshi RK. Clinical Evaluation of Efficacy of Alambushadi Ghana Vati and Vaitarana Basti in the Management of Amavata With Special Reference to Rheumatoid Arthritis. Ayu. 2016 Apr-Jun;37(2):105-112. PubMed PMID: 29200748.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical evaluation of efficacy of Alambushadi Ghana Vati and Vaitarana Basti in the management of Amavata with special reference to rheumatoid arthritis. AU - Sasane,Prashant, AU - Saroj,Udai Raj, AU - Joshi,Ram Kishor, PY - 2017/12/5/entrez PY - 2016/4/1/pubmed PY - 2016/4/1/medline KW - Alambushadi Ghana Vati KW - Amavata KW - Vaitarana Basti KW - rheumatoid arthritis SP - 105 EP - 112 JF - Ayu JO - Ayu VL - 37 IS - 2 N2 - The clinical presentation of Amavata closely mimics with the special variety of rheumatologic disorders called rheumatoid arthritis (RA). The Ayurvedic approach toward the treatment of Amavata is the need of present era as no system is successful in providing the complete cure to this disease. Amavata is a challenging and a burning problem of medical science. Prevalence of RA is approximately 0.8% of the population. Due to wide spectrum of disease, much prevalence in the society, and lack of effective medicine, the disease had been chosen for the study. The aim of the research was to study the efficacy of Alambushadi Ghana Vati and Vaitarana Basti in the management of Amavata (RA). It was a single-center, randomized, open-clinical study. In the present study, 30 clinically diagnosed patients of Amavata were selected and randomly divided into two groups by lottery method. Alambushadi Ghana Vati was given in dose of two tablets (each 500 mg) three times in a day with lukewarm water after meal for 30 days, while Vaitarana Basti on alternate day (15 Basti) had been given simultaneously in the second group along with drug of first group. Statistical analysis was done using InStat GraphPad 3 Software. Wilcoxon matched pairs signed ranks test was used for the analysis of nonparametric data, while paired t-test was used for parametric data analysis and Mann-Whitney test and unpaired t-test were used for intergroup comparison. Statistically highly significant (HS) improvement was found in erythrocyte sedimentation rate, and HS results were found in symptoms of Amavata when the Vaitarana Basti was used along with Alambushadi Ghana Vati. With excellent relief in 20% patients, significant relief in 60% patients, moderate relief in 13.33% patients, whereas mild relief in 6.66% patients. On comparing the effect of two therapies, it can be concluded that Group B (Alambushadi Ghana Vati and Vaitarana Basti) provided better relief than Group A (Alambushadi Ghana Vati) in most of the sign and symptom of the disease at significant level. SN - 0974-8520 UR - https://www.unboundmedicine.com/medline/citation/29200748/Clinical_evaluation_of_efficacy_of_Alambushadi_Ghana_Vati_and_Vaitarana_Basti_in_the_management_of_Amavata_with_special_reference_to_rheumatoid_arthritis_ L2 - http://www.ayujournal.org/article.asp?issn=0974-8520;year=2016;volume=37;issue=2;spage=105;epage=112;aulast=Sasane DB - PRIME DP - Unbound Medicine ER -
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