Tags

Type your tag names separated by a space and hit enter

A Mediterranean-style dietary intervention supplemented with fish oil improves diet quality and mental health in people with depression: A randomized controlled trial (HELFIMED).
Nutr Neurosci. 2019 Jul; 22(7):474-487.NN

Abstract

OBJECTIVES

We investigated whether a Mediterranean-style diet (MedDiet) supplemented with fish oil can improve mental health in adults suffering depression.

METHODS

Adults with self-reported depression were randomized to receive fortnightly food hampers and MedDiet cooking workshops for 3 months and fish oil supplements for 6 months, or attend social groups fortnightly for 3 months. Assessments at baseline, 3 and 6 months included mental health, quality of life (QoL) and dietary questionnaires, and blood samples for erythrocyte fatty acid analysis.

RESULTS

n = 152 eligible adults aged 18-65 were recruited (n = 95 completed 3-month and n = 85 completed 6-month assessments). At 3 months, the MedDiet group had a higher MedDiet score (t = 3.95, P < 0.01), consumed more vegetables (t = 3.95, P < 0.01), fruit (t = 2.10, P = 0.04), nuts (t = 2.29, P = 0.02), legumes (t = 2.41, P = 0.02) wholegrains (t = 2.63, P = 0.01), and vegetable diversity (t = 3.27, P < 0.01); less unhealthy snacks (t = -2.10, P = 0.04) and red meat/chicken (t = -2.13, P = 0.04). The MedDiet group had greater reduction in depression (t = -2.24, P = 0.03) and improved mental health QoL scores (t = 2.10, P = 0.04) at 3 months. Improved diet and mental health were sustained at 6 months. Reduced depression was correlated with an increased MedDiet score (r = -0.298, P = 0.01), nuts (r = -0.264, P = 0.01), and vegetable diversity (r = -0.303, P = 0.01). Other mental health improvements had similar correlations, most notably for increased vegetable diversity and legumes. There were some correlations between increased omega-3, decreased omega-6 and improved mental health.

DISCUSSION

This is one of the first randomized controlled trials to show that healthy dietary changes are achievable and, supplemented with fish oil, can improve mental health in people with depression.

Authors+Show Affiliations

a Centre for Population Health Research , University of South Australia , GPO Box 2471, Adelaide , South Australia 5001 , Australia.a Centre for Population Health Research , University of South Australia , GPO Box 2471, Adelaide , South Australia 5001 , Australia.a Centre for Population Health Research , University of South Australia , GPO Box 2471, Adelaide , South Australia 5001 , Australia.b Ehrenberg-Bass Institute for Marketing Science , University of South Australia , GPO Box 2471, Adelaide , South Australia 5001 , Australia.b Ehrenberg-Bass Institute for Marketing Science , University of South Australia , GPO Box 2471, Adelaide , South Australia 5001 , Australia.c Faculty of Science, Health, Education and Engineering , University of the Sunshine Coast , 90 Sippy Downs, Sippy Downs , Queensland 4556 , Australia.d Discipline of Dietetics and Human Nutrition , La Trobe University , Melbourne , Victoria 3086 , Australia.a Centre for Population Health Research , University of South Australia , GPO Box 2471, Adelaide , South Australia 5001 , Australia. e Centre for Research and Action in Public Health, Faculty of Health , University of Canberra , Canberra , Australian Capital Territory , Australia.f School of Human Health and Social Sciences , Central Queensland University , 44 Greenhill Road, Wayville , South Australia 5034 , Australia.g School of Medicine , University of Wollongong , Northfields Avenue, Wollongong , NSW 2522 , Australia.a Centre for Population Health Research , University of South Australia , GPO Box 2471, Adelaide , South Australia 5001 , Australia.h Discipline of Psychiatry, School of Medicine , Royal Adelaide Hospital, University of Adelaide , Level 4, Eleanor Harrald Building, Adelaide 5005 , Australia.a Centre for Population Health Research , University of South Australia , GPO Box 2471, Adelaide , South Australia 5001 , Australia.

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

29215971

Citation

Parletta, Natalie, et al. "A Mediterranean-style Dietary Intervention Supplemented With Fish Oil Improves Diet Quality and Mental Health in People With Depression: a Randomized Controlled Trial (HELFIMED)." Nutritional Neuroscience, vol. 22, no. 7, 2019, pp. 474-487.
Parletta N, Zarnowiecki D, Cho J, et al. A Mediterranean-style dietary intervention supplemented with fish oil improves diet quality and mental health in people with depression: A randomized controlled trial (HELFIMED). Nutr Neurosci. 2019;22(7):474-487.
Parletta, N., Zarnowiecki, D., Cho, J., Wilson, A., Bogomolova, S., Villani, A., Itsiopoulos, C., Niyonsenga, T., Blunden, S., Meyer, B., Segal, L., Baune, B. T., & O'Dea, K. (2019). A Mediterranean-style dietary intervention supplemented with fish oil improves diet quality and mental health in people with depression: A randomized controlled trial (HELFIMED). Nutritional Neuroscience, 22(7), 474-487. https://doi.org/10.1080/1028415X.2017.1411320
Parletta N, et al. A Mediterranean-style Dietary Intervention Supplemented With Fish Oil Improves Diet Quality and Mental Health in People With Depression: a Randomized Controlled Trial (HELFIMED). Nutr Neurosci. 2019;22(7):474-487. PubMed PMID: 29215971.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A Mediterranean-style dietary intervention supplemented with fish oil improves diet quality and mental health in people with depression: A randomized controlled trial (HELFIMED). AU - Parletta,Natalie, AU - Zarnowiecki,Dorota, AU - Cho,Jihyun, AU - Wilson,Amy, AU - Bogomolova,Svetlana, AU - Villani,Anthony, AU - Itsiopoulos,Catherine, AU - Niyonsenga,Theo, AU - Blunden,Sarah, AU - Meyer,Barbara, AU - Segal,Leonie, AU - Baune,Bernhard T, AU - O'Dea,Kerin, Y1 - 2017/12/07/ PY - 2017/12/8/pubmed PY - 2019/7/2/medline PY - 2017/12/8/entrez KW - Depression KW - Fish oil KW - Intervention KW - Mediterranean diet KW - Mental health KW - Omega-3 KW - Omega-6 KW - Quality of life SP - 474 EP - 487 JF - Nutritional neuroscience JO - Nutr Neurosci VL - 22 IS - 7 N2 - OBJECTIVES: We investigated whether a Mediterranean-style diet (MedDiet) supplemented with fish oil can improve mental health in adults suffering depression. METHODS: Adults with self-reported depression were randomized to receive fortnightly food hampers and MedDiet cooking workshops for 3 months and fish oil supplements for 6 months, or attend social groups fortnightly for 3 months. Assessments at baseline, 3 and 6 months included mental health, quality of life (QoL) and dietary questionnaires, and blood samples for erythrocyte fatty acid analysis. RESULTS: n = 152 eligible adults aged 18-65 were recruited (n = 95 completed 3-month and n = 85 completed 6-month assessments). At 3 months, the MedDiet group had a higher MedDiet score (t = 3.95, P < 0.01), consumed more vegetables (t = 3.95, P < 0.01), fruit (t = 2.10, P = 0.04), nuts (t = 2.29, P = 0.02), legumes (t = 2.41, P = 0.02) wholegrains (t = 2.63, P = 0.01), and vegetable diversity (t = 3.27, P < 0.01); less unhealthy snacks (t = -2.10, P = 0.04) and red meat/chicken (t = -2.13, P = 0.04). The MedDiet group had greater reduction in depression (t = -2.24, P = 0.03) and improved mental health QoL scores (t = 2.10, P = 0.04) at 3 months. Improved diet and mental health were sustained at 6 months. Reduced depression was correlated with an increased MedDiet score (r = -0.298, P = 0.01), nuts (r = -0.264, P = 0.01), and vegetable diversity (r = -0.303, P = 0.01). Other mental health improvements had similar correlations, most notably for increased vegetable diversity and legumes. There were some correlations between increased omega-3, decreased omega-6 and improved mental health. DISCUSSION: This is one of the first randomized controlled trials to show that healthy dietary changes are achievable and, supplemented with fish oil, can improve mental health in people with depression. SN - 1476-8305 UR - https://www.unboundmedicine.com/medline/citation/29215971/A_Mediterranean_style_dietary_intervention_supplemented_with_fish_oil_improves_diet_quality_and_mental_health_in_people_with_depression:_A_randomized_controlled_trial__HELFIMED__ L2 - http://www.tandfonline.com/doi/full/10.1080/1028415X.2017.1411320 DB - PRIME DP - Unbound Medicine ER -