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[Effect of morphine in cancer pain].
Gan No Rinsho. 1989 Jan; 35(1):51-4.GN

Abstract

The usefulness of oral morphine to alleviate pain has been tested in 70 patients with cancer. The efficacy was found to be 87% (61/70). The starting dose was 10 mg/d-12 mg/d (mean 36 mg/d), and the maximum dose was 10 mg/d-3,600 mg/d. Twenty four of these patients were able to stay at home or go to the hospital for dose treatment. In 27 patients, oral morphine dose were able to administrated until death. Although vomiting and constipation were frequent side effects, the administration of adjuvant drugs relieved these symptoms. It was found that these oral morphine doses did not shorten a patient's life span. Thus we have concluded that oral morphine proved a useful, safe, and convenient drug for the control of cancer pain.

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Authors+Show Affiliations

Nukariya N
National Matsudo Hospital.
Nishiwaki Y
No affiliation info available
Kodama T
No affiliation info available
Inoue Y
No affiliation info available
Hayashibe A
No affiliation info available
Murasugi M
No affiliation info available
Kuroki M
No affiliation info available
Takahashi K
No affiliation info available
Nishiyama Y
No affiliation info available
Kitaya T
No affiliation info available

MeSH

Administration, OralAdultAgedBone NeoplasmsDrug Administration ScheduleFemaleHumansLung NeoplasmsMaleMiddle AgedMorphinePain, Intractable

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

jpn

PubMed ID

2921810

Citation

Nukariya, N, et al. "[Effect of Morphine in Cancer Pain]." Gan No Rinsho. Japan Journal of Cancer Clinics, vol. 35, no. 1, 1989, pp. 51-4.
Nukariya N, Nishiwaki Y, Kodama T, et al. [Effect of morphine in cancer pain]. Gan No Rinsho. 1989;35(1):51-4.
Nukariya, N., Nishiwaki, Y., Kodama, T., Inoue, Y., Hayashibe, A., Murasugi, M., Kuroki, M., Takahashi, K., Nishiyama, Y., & Kitaya, T. (1989). [Effect of morphine in cancer pain]. Gan No Rinsho. Japan Journal of Cancer Clinics, 35(1), 51-4.
Nukariya N, et al. [Effect of Morphine in Cancer Pain]. Gan No Rinsho. 1989;35(1):51-4. PubMed PMID: 2921810.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Effect of morphine in cancer pain]. A1 - Nukariya,N, AU - Nishiwaki,Y, AU - Kodama,T, AU - Inoue,Y, AU - Hayashibe,A, AU - Murasugi,M, AU - Kuroki,M, AU - Takahashi,K, AU - Nishiyama,Y, AU - Kitaya,T, PY - 1989/1/1/pubmed PY - 1989/1/1/medline PY - 1989/1/1/entrez SP - 51 EP - 4 JF - Gan no rinsho. Japan journal of cancer clinics JO - Gan No Rinsho VL - 35 IS - 1 N2 - The usefulness of oral morphine to alleviate pain has been tested in 70 patients with cancer. The efficacy was found to be 87% (61/70). The starting dose was 10 mg/d-12 mg/d (mean 36 mg/d), and the maximum dose was 10 mg/d-3,600 mg/d. Twenty four of these patients were able to stay at home or go to the hospital for dose treatment. In 27 patients, oral morphine dose were able to administrated until death. Although vomiting and constipation were frequent side effects, the administration of adjuvant drugs relieved these symptoms. It was found that these oral morphine doses did not shorten a patient's life span. Thus we have concluded that oral morphine proved a useful, safe, and convenient drug for the control of cancer pain. SN - 0021-4949 UR - https://www.unboundmedicine.com/medline/citation/2921810/[Effect_of_morphine_in_cancer_pain]_ L2 - https://www.medicalonline.jp/meteo_linkout.php?issn=0021-4949&volume=35&issue=1&spage=51 DB - PRIME DP - Unbound Medicine ER -