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[Research on compatibility of prescriptions including Ginseng Radix et Rhizoma and Trogopterus Dung based on complex network analysis].
Zhongguo Zhong Yao Za Zhi. 2017 Sep; 42(18):3623-3627.ZZ

Abstract

The applications of prescriptions including Ginseng Radix et Rhizoma and Trogopterus Dung in contemporary literatures from 1949 to 2016 are compiled and the data mining techniques containing scale-free complex network method are utilized to explore its practical characteristics, with comparison between modern and ancient ones. The results indicate that malignant neoplasms, coronary heart disease which present Qi deficiency and blood stasis type are the main diseases treated by prescriptions including Ginseng Radix et Rhizoma and Trogopterus Dung according to the reports during 1949 to 2016. The complex network connection shows that Glycyrrhizae Radixet Rhizoma, Angelicae Sinensis Radix, Astragali Radix, Typhae Pollen, Salviae Miltiorrhizae Radix et Rhizoma are the primary drugs related to Ginseng Radix et Rhizoma and Trogopterus Dung. The next are Paeoniae Radix Alba, Atractylodis Macrocephalae Rhizoma, Persicae Semen, Foria, et al. Carthami Flos, Notoginseng Radix et Rhizoma, Cyperi Rhizoma, Bupleuri Radix are the peripheral ones. Also, Ginseng Radix et Rhizoma-Glycyrrhizae Radixet Rhizoma, Trogopterus Dung-Glycyrrhizae Radixet Rhizoma, Ginseng Radix et Rhizoma-Angelicae Sinensis Radix, Trogopterus Dung-Angelicae Sinensis Radix, Ginseng Radix et Rhizoma-Astragali Radix, Trogopterus Dung-Astragali Radix are the main paired drugs. The paired drugs including Ginseng Radix et Rhizoma-Trogopterus Dung-Glycyrrhizae Radixet Rhizoma, Ginseng Radix et Rhizoma-Trogopterus Dung-Angelicae Sinensis Radix, Ginseng Radix et Rhizoma-Trogopterus Dung-Astragali Radix, Ginseng Radix et Rhizoma-Trogopterus Dung-Typhae Pollen have a higher support degree. The main compatible drugs are different in ancient and modern prescriptions including Ginseng Radix et Rhizoma and Trogopterus Dung. Notoginseng Radix et Rhizoma, Typhae Pollen, Salviae Miltiorrhizae Radix et Rhizoma, Astragali Radix are utilized frequently in modern prescriptions while less used in ancient ones. It is also shown that more attentions are paid to the drugs contributing to invigorating Qi and promoting blood circulation in modern times with comparative results between modern and ancient prescriptions.

Authors+Show Affiliations

Institute of Traditional Chinese Medicine Literature Research, Nanjing University of Chinese Medicine, Nanjing 210023, China. School of Basic Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.Institute of Traditional Chinese Medicine Literature Research, Nanjing University of Chinese Medicine, Nanjing 210023, China. School of Basic Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.Institute of Traditional Chinese Medicine Literature Research, Nanjing University of Chinese Medicine, Nanjing 210023, China. School of Basic Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.Key Laboratory of Computer Software New Technology National, Nanjing University, Nanjing 210046, China.

Pub Type(s)

Journal Article

Language

chi

PubMed ID

29218951

Citation

Li, Meng-Wen, et al. "[Research On Compatibility of Prescriptions Including Ginseng Radix Et Rhizoma and Trogopterus Dung Based On Complex Network Analysis]." Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, vol. 42, no. 18, 2017, pp. 3623-3627.
Li MW, Fan XS, Zhang LS, et al. [Research on compatibility of prescriptions including Ginseng Radix et Rhizoma and Trogopterus Dung based on complex network analysis]. Zhongguo Zhong Yao Za Zhi. 2017;42(18):3623-3627.
Li, M. W., Fan, X. S., Zhang, L. S., & Wang, C. J. (2017). [Research on compatibility of prescriptions including Ginseng Radix et Rhizoma and Trogopterus Dung based on complex network analysis]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, 42(18), 3623-3627. https://doi.org/10.19540/j.cnki.cjcmm.2017.0140
Li MW, et al. [Research On Compatibility of Prescriptions Including Ginseng Radix Et Rhizoma and Trogopterus Dung Based On Complex Network Analysis]. Zhongguo Zhong Yao Za Zhi. 2017;42(18):3623-3627. PubMed PMID: 29218951.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Research on compatibility of prescriptions including Ginseng Radix et Rhizoma and Trogopterus Dung based on complex network analysis]. AU - Li,Meng-Wen, AU - Fan,Xin-Sheng, AU - Zhang,Ling-Shan, AU - Wang,Cong-Jun, PY - 2017/05/05/received PY - 2017/12/9/entrez PY - 2017/12/9/pubmed PY - 2019/4/24/medline KW - Ginseng-Trogopterus Dung KW - application characteristics KW - nineteen medicaments of mutual restraint KW - scale-free complex network method SP - 3623 EP - 3627 JF - Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica JO - Zhongguo Zhong Yao Za Zhi VL - 42 IS - 18 N2 - The applications of prescriptions including Ginseng Radix et Rhizoma and Trogopterus Dung in contemporary literatures from 1949 to 2016 are compiled and the data mining techniques containing scale-free complex network method are utilized to explore its practical characteristics, with comparison between modern and ancient ones. The results indicate that malignant neoplasms, coronary heart disease which present Qi deficiency and blood stasis type are the main diseases treated by prescriptions including Ginseng Radix et Rhizoma and Trogopterus Dung according to the reports during 1949 to 2016. The complex network connection shows that Glycyrrhizae Radixet Rhizoma, Angelicae Sinensis Radix, Astragali Radix, Typhae Pollen, Salviae Miltiorrhizae Radix et Rhizoma are the primary drugs related to Ginseng Radix et Rhizoma and Trogopterus Dung. The next are Paeoniae Radix Alba, Atractylodis Macrocephalae Rhizoma, Persicae Semen, Foria, et al. Carthami Flos, Notoginseng Radix et Rhizoma, Cyperi Rhizoma, Bupleuri Radix are the peripheral ones. Also, Ginseng Radix et Rhizoma-Glycyrrhizae Radixet Rhizoma, Trogopterus Dung-Glycyrrhizae Radixet Rhizoma, Ginseng Radix et Rhizoma-Angelicae Sinensis Radix, Trogopterus Dung-Angelicae Sinensis Radix, Ginseng Radix et Rhizoma-Astragali Radix, Trogopterus Dung-Astragali Radix are the main paired drugs. The paired drugs including Ginseng Radix et Rhizoma-Trogopterus Dung-Glycyrrhizae Radixet Rhizoma, Ginseng Radix et Rhizoma-Trogopterus Dung-Angelicae Sinensis Radix, Ginseng Radix et Rhizoma-Trogopterus Dung-Astragali Radix, Ginseng Radix et Rhizoma-Trogopterus Dung-Typhae Pollen have a higher support degree. The main compatible drugs are different in ancient and modern prescriptions including Ginseng Radix et Rhizoma and Trogopterus Dung. Notoginseng Radix et Rhizoma, Typhae Pollen, Salviae Miltiorrhizae Radix et Rhizoma, Astragali Radix are utilized frequently in modern prescriptions while less used in ancient ones. It is also shown that more attentions are paid to the drugs contributing to invigorating Qi and promoting blood circulation in modern times with comparative results between modern and ancient prescriptions. SN - 1001-5302 UR - https://www.unboundmedicine.com/medline/citation/29218951/[Research_on_compatibility_of_prescriptions_including_Ginseng_Radix_et_Rhizoma_and_Trogopterus_Dung_based_on_complex_network_analysis]_ DB - PRIME DP - Unbound Medicine ER -