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[Genetic Polymorphisms of 17 Y-STR Loci in Nantong Han Population].
Fa Yi Xue Za Zhi. 2017 Aug; 33(4):383-387.FY

Abstract

OBJECTIVES

To analyze the genetic phenotypes of Nantong Han population and evaluate the application value of 17 Y-STR loci in Nantong population.

METHODS

The peripheral blood samples were collected from 343 unrelated Nantong Han males and the genomic DNA were extracted by Chelex-100 method. Genotyping was performed using the AmpFℓSTR Yfiler™ Kit. The results were compared with other 12 Han populations, including Anhui, Jiangsu, Jiangxi, Shandong, Shanghai, Zhejiang (1), Lanzhou, Nanyang, Luzhou, Mudanjiang, Shanxi and Zhejiang (2), and 9 minority populations (Mongol, Xibe, Tibetan in Lhasa, Tibetan in Qinghai, Kazak, Uighur, Manchu, Paiwan in Taiwan and Tujia).

RESULTS

A total of 327 different haplotypes were found in 17 Y-STR loci in Nantong Han population. The haplotype diversity (HD) was 0.999 7. The Rst value between Nantong Han and other Chinese populations ranged from -0.000 6 to 0.263 5. The multidimensional scaling results showed that Nantong Han population had no significant differences between most of the Han populations, but had significant differences between most of Chinese minority populations.

CONCLUSIONS

Seventeen Y-STR loci can be a powerful tool for forensic application because of its high polymorphism in Nantong Han population.

Authors+Show Affiliations

School of Life Science, Fudan University, Shanghai 200438, China. Nantong Municipal Public Security Bureau, Nantong 226007, China.School of Life Science, Fudan University, Shanghai 200438, China.Nantong Municipal Public Security Bureau, Nantong 226007, China.Nantong Municipal Public Security Bureau, Nantong 226007, China.Nantong Municipal Public Security Bureau, Nantong 226007, China.Nantong Municipal Public Security Bureau, Nantong 226007, China.Nantong Municipal Public Security Bureau, Nantong 226007, China.Nantong Municipal Public Security Bureau, Nantong 226007, China.School of Life Science, Fudan University, Shanghai 200438, China.

Pub Type(s)

Journal Article

Language

chi

PubMed ID

29219270

Citation

Yang, M, et al. "[Genetic Polymorphisms of 17 Y-STR Loci in Nantong Han Population]." Fa Yi Xue Za Zhi, vol. 33, no. 4, 2017, pp. 383-387.
Yang M, Xu SX, Qin HY, et al. [Genetic Polymorphisms of 17 Y-STR Loci in Nantong Han Population]. Fa Yi Xue Za Zhi. 2017;33(4):383-387.
Yang, M., Xu, S. X., Qin, H. Y., Zhang, H., Yi, H., Han, H. J., Dong, D. T., Zhang, Y. H., & Li, S. L. (2017). [Genetic Polymorphisms of 17 Y-STR Loci in Nantong Han Population]. Fa Yi Xue Za Zhi, 33(4), 383-387. https://doi.org/10.3969/j.issn.1004-5619.2017.04.011
Yang M, et al. [Genetic Polymorphisms of 17 Y-STR Loci in Nantong Han Population]. Fa Yi Xue Za Zhi. 2017;33(4):383-387. PubMed PMID: 29219270.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Genetic Polymorphisms of 17 Y-STR Loci in Nantong Han Population]. AU - Yang,M, AU - Xu,S X, AU - Qin,H Y, AU - Zhang,H, AU - Yi,H, AU - Han,H J, AU - Dong,D T, AU - Zhang,Y H, AU - Li,S L, Y1 - 2017/08/25/ PY - 2015/12/14/received PY - 2017/12/9/entrez PY - 2017/12/9/pubmed PY - 2018/4/24/medline KW - Han population KW - Nantong KW - Y chromosome KW - forensic genetics KW - polymorphism, genetic KW - short tandem repeat SP - 383 EP - 387 JF - Fa yi xue za zhi JO - Fa Yi Xue Za Zhi VL - 33 IS - 4 N2 - OBJECTIVES: To analyze the genetic phenotypes of Nantong Han population and evaluate the application value of 17 Y-STR loci in Nantong population. METHODS: The peripheral blood samples were collected from 343 unrelated Nantong Han males and the genomic DNA were extracted by Chelex-100 method. Genotyping was performed using the AmpFℓSTR Yfiler™ Kit. The results were compared with other 12 Han populations, including Anhui, Jiangsu, Jiangxi, Shandong, Shanghai, Zhejiang (1), Lanzhou, Nanyang, Luzhou, Mudanjiang, Shanxi and Zhejiang (2), and 9 minority populations (Mongol, Xibe, Tibetan in Lhasa, Tibetan in Qinghai, Kazak, Uighur, Manchu, Paiwan in Taiwan and Tujia). RESULTS: A total of 327 different haplotypes were found in 17 Y-STR loci in Nantong Han population. The haplotype diversity (HD) was 0.999 7. The Rst value between Nantong Han and other Chinese populations ranged from -0.000 6 to 0.263 5. The multidimensional scaling results showed that Nantong Han population had no significant differences between most of the Han populations, but had significant differences between most of Chinese minority populations. CONCLUSIONS: Seventeen Y-STR loci can be a powerful tool for forensic application because of its high polymorphism in Nantong Han population. SN - 1004-5619 UR - https://www.unboundmedicine.com/medline/citation/29219270/[Genetic_Polymorphisms_of_17_Y_STR_Loci_in_Nantong_Han_Population]_ DB - PRIME DP - Unbound Medicine ER -