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[The "regulating conception-governor vessel" acupuncture method for infertility of polycystic ovarian syndrome].
Zhongguo Zhen Jiu. 2016 Dec 12; 36(12):1237-1241.ZZ

Abstract

OBJECTIVE

To compare clinical efficacy differences between"regulating conception-governor vessel" acupuncture method and clomiphene for infertility of polycystic ovarian syndrome (PCOS).

METHODS

One hundred patients of PCOS were randomly assigned into an observation group and a control group, 50 cases in each one. The patients in the observation group were treated with"regulating Conception-Governor Vessel" acupuncture method at Zhongwan (CV 12), Guanyuan (CV 4), Qihai (CV 6), Zhongji (CV 3), Mingmen (GV 4), Yaoyangguan (GV 3) and Yaoshu (GV 2). The acupuncture treatment started at the end of menstruation, once every other day; after four treatments, the follicle was tested with B ultrasound; when follicle was longer than 18 mm or above, the acupuncture treatment was given once a day until follicle was discharged and acupuncture treatment finished. The patients in the control group were treated with oral administration of clomiphene from 5 days into menstruation, 50 mg per day for 5 consecutive days. Both groups were treated for three menstruation cycle. The menstrual cycles, endometrial thickness, endometrium types (A, B and C), cervical mucus scores, basal body temperature (BBT), cases of ovulation, cases of pregnancy were observed.The levels of follicle stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), prolactin (PRL), progesterone (P) and testosterone (T) in serum were detected before and after the treatment.

RESULTS

After the treatment, the menstrual cycles were shortened (both P<0.05),the endometrial thickness and cervical mucus scores were increased in the two groups (P<0.05, P<0.01); the improvement of endometrial thickness and cervical mucus score in the observation group were higher than those in the control group (both P<0.01). The percentages of type-A endometrium in both groups were higher than those before the treatment (both P<0.05); the number of type-A endometrium in the observation group was higher than that in the control group (P<0.05). The ovulation rate was 88.0% (44/50) in the observation group, which was superior to 70.0% (35/50) in the control group (P<0.05). After treatment, the levels of LH were reduced in the two groups (P<0.05, P<0.01), which was more significant in the observation group (P<0.05).

CONCLUSIONS

The"regulating Conception-Governor Vessel" acupuncture method could improve menstrual cycles, increase endomet-rial thickness and promote the development of follicles in PCOS patient; in addition, it could decrease serum LH level, improve the ovarian functions and increase ovulation rate, which is superior to oral administration of clomiphene.

Authors+Show Affiliations

Department of Acupuncture and Moxibustion, Shenzhen TCM Hospital, Shenzhen 518033, Guangdong Province, China.Department of TCM, Shenzhen Maternal and Child Health Hospital.Department of Acupuncture and Moxibustion, Shenzhen TCM Hospital, Shenzhen 518033, Guangdong Province, China.Department of Acupuncture and Moxibustion, Shenzhen TCM Hospital, Shenzhen 518033, Guangdong Province, China.Department of TCM, Shenzhen Maternal and Child Health Hospital.Department of Acupuncture and Moxibustion, Shenzhen TCM Hospital, Shenzhen 518033, Guangdong Province, China.

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

chi

PubMed ID

29231358

Citation

Zhuo, Yuanyuan, et al. "[The "regulating Conception-governor Vessel" Acupuncture Method for Infertility of Polycystic Ovarian Syndrome]." Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, vol. 36, no. 12, 2016, pp. 1237-1241.
Zhuo Y, Wu J, Lin W, et al. [The "regulating conception-governor vessel" acupuncture method for infertility of polycystic ovarian syndrome]. Zhongguo Zhen Jiu. 2016;36(12):1237-1241.
Zhuo, Y., Wu, J., Lin, W., Pi, M., Chen, P., & Yang, Z. (2016). [The "regulating conception-governor vessel" acupuncture method for infertility of polycystic ovarian syndrome]. Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, 36(12), 1237-1241. https://doi.org/10.13703/j.0255-2930.2016.12.002
Zhuo Y, et al. [The "regulating Conception-governor Vessel" Acupuncture Method for Infertility of Polycystic Ovarian Syndrome]. Zhongguo Zhen Jiu. 2016 Dec 12;36(12):1237-1241. PubMed PMID: 29231358.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The "regulating conception-governor vessel" acupuncture method for infertility of polycystic ovarian syndrome]. AU - Zhuo,Yuanyuan, AU - Wu,Jiaman, AU - Lin,Wanshan, AU - Pi,Min, AU - Chen,Pengdian, AU - Yang,Zhuoxin, PY - 2017/12/13/entrez PY - 2017/12/13/pubmed PY - 2018/6/21/medline KW - RCT KW - acupuncture KW - polycystic ovarian syndrome (PCOS) KW - regulating conception-governor vessel SP - 1237 EP - 1241 JF - Zhongguo zhen jiu = Chinese acupuncture & moxibustion JO - Zhongguo Zhen Jiu VL - 36 IS - 12 N2 - OBJECTIVE: To compare clinical efficacy differences between"regulating conception-governor vessel" acupuncture method and clomiphene for infertility of polycystic ovarian syndrome (PCOS). METHODS: One hundred patients of PCOS were randomly assigned into an observation group and a control group, 50 cases in each one. The patients in the observation group were treated with"regulating Conception-Governor Vessel" acupuncture method at Zhongwan (CV 12), Guanyuan (CV 4), Qihai (CV 6), Zhongji (CV 3), Mingmen (GV 4), Yaoyangguan (GV 3) and Yaoshu (GV 2). The acupuncture treatment started at the end of menstruation, once every other day; after four treatments, the follicle was tested with B ultrasound; when follicle was longer than 18 mm or above, the acupuncture treatment was given once a day until follicle was discharged and acupuncture treatment finished. The patients in the control group were treated with oral administration of clomiphene from 5 days into menstruation, 50 mg per day for 5 consecutive days. Both groups were treated for three menstruation cycle. The menstrual cycles, endometrial thickness, endometrium types (A, B and C), cervical mucus scores, basal body temperature (BBT), cases of ovulation, cases of pregnancy were observed.The levels of follicle stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), prolactin (PRL), progesterone (P) and testosterone (T) in serum were detected before and after the treatment. RESULTS: After the treatment, the menstrual cycles were shortened (both P<0.05),the endometrial thickness and cervical mucus scores were increased in the two groups (P<0.05, P<0.01); the improvement of endometrial thickness and cervical mucus score in the observation group were higher than those in the control group (both P<0.01). The percentages of type-A endometrium in both groups were higher than those before the treatment (both P<0.05); the number of type-A endometrium in the observation group was higher than that in the control group (P<0.05). The ovulation rate was 88.0% (44/50) in the observation group, which was superior to 70.0% (35/50) in the control group (P<0.05). After treatment, the levels of LH were reduced in the two groups (P<0.05, P<0.01), which was more significant in the observation group (P<0.05). CONCLUSIONS: The"regulating Conception-Governor Vessel" acupuncture method could improve menstrual cycles, increase endomet-rial thickness and promote the development of follicles in PCOS patient; in addition, it could decrease serum LH level, improve the ovarian functions and increase ovulation rate, which is superior to oral administration of clomiphene. SN - 0255-2930 UR - https://www.unboundmedicine.com/medline/citation/29231358/[The_"regulating_conception_governor_vessel"_acupuncture_method_for_infertility_of_polycystic_ovarian_syndrome]_ DB - PRIME DP - Unbound Medicine ER -