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[Long-snake moxibustion for rheumatoid arthritis:a randomized controlled trial].
Zhongguo Zhen Jiu 2016; 36(7):694-698ZZ

Abstract

OBJECTIVE

To observe the clinical efficacy differences among long-snake moxibustion, warm needling and western medication on rheumatoid arthritis and explore its effect mechanism.

METHODS

One hundred and twenty patients were randomized into a long-snake moxibustion group, a warm needling group and a western medication group, 40 cases in each one. In the long-snake moxibustion group, the long-snake moxibustion was used. The ginger-isolated moxibustion was applied along the governor vessel, from Dazhui (GV 14) to Yaoshu (GV 2), once a month, for 2 months. In the warm needling group, the main points included Dazhui (GV 14), Ganshu (BL 18), Pishu (BL 20), Shenshu (BL 23), Zhiyang (GV 9), Mingmen (GV 4) and Yaoyangguan (GV 3). The warm needling technique was used at 4 to 5 points each time, and 3 moxa cones were required at each points. The treatment was given once every two days, for 2 months. In the western medication group, methotrexate was prescribed for oral administration, 10 mg each time, once a week. If the joint pain score or joint swelling score was up to 6, diclofenac sodium was combined, 25 mg each time, 3 times a day, for 2 months. The symptom score, physical sign score, the visual analogue scale (VAS) score, levels of rheumatoid factor (RF), erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), immunoglobulin M (IgM) and immunoglobulin G (IgG) were observed before and after treatment in the patients of the three groups.

RESULTS

The treatments relieved the symptoms and physical signs of rheumatoid arthritis and improved VAS score and the levels of serum RF, ESR, CRP, IgM and IgG in all of the three groups (all P<0.01). The efficacy in the long-snake moxibustion group was significantly better than that in the warm needling group and the western medication group (P<0.05, P<0.01).

CONCLUSIONS

The long-snake moxibustion achieves the significant clinical efficacy on rheumatoid arthritis, better than warm needling therapy and methotrexate. This therapy much better reduces immune response and alleviates the sickness.

Authors+Show Affiliations

Department of Acupuncture and Moxibustion, Affiliated Hospital of Jiangxi University of TCM, Nanchang 330006, China.Department of Acupuncture and Moxibustion, Affiliated Hospital of Jiangxi University of TCM, Nanchang 330006, China.Department of Acupuncture and Moxibustion, Affiliated Hospital of Jiangxi University of TCM, Nanchang 330006, China.

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

chi

PubMed ID

29231407

Citation

Zhang, Wei, et al. "[Long-snake Moxibustion for Rheumatoid Arthritis:a Randomized Controlled Trial]." Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, vol. 36, no. 7, 2016, pp. 694-698.
Zhang W, Chen M, Hu J. [Long-snake moxibustion for rheumatoid arthritis:a randomized controlled trial]. Zhongguo Zhen Jiu. 2016;36(7):694-698.
Zhang, W., Chen, M., & Hu, J. (2016). [Long-snake moxibustion for rheumatoid arthritis:a randomized controlled trial]. Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, 36(7), pp. 694-698. doi:10.13703/j.0255-2930.2016.07.005.
Zhang W, Chen M, Hu J. [Long-snake Moxibustion for Rheumatoid Arthritis:a Randomized Controlled Trial]. Zhongguo Zhen Jiu. 2016 Jul 12;36(7):694-698. PubMed PMID: 29231407.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Long-snake moxibustion for rheumatoid arthritis:a randomized controlled trial]. AU - Zhang,Wei, AU - Chen,Mingren, AU - Hu,Jinyu, PY - 2017/12/13/entrez PY - 2016/7/12/pubmed PY - 2018/6/14/medline KW - long-snake moxibustion KW - methotrexate KW - randomized controlled trial (RCT) KW - rheumatoid arthritis KW - warm needling therapy SP - 694 EP - 698 JF - Zhongguo zhen jiu = Chinese acupuncture & moxibustion JO - Zhongguo Zhen Jiu VL - 36 IS - 7 N2 - OBJECTIVE: To observe the clinical efficacy differences among long-snake moxibustion, warm needling and western medication on rheumatoid arthritis and explore its effect mechanism. METHODS: One hundred and twenty patients were randomized into a long-snake moxibustion group, a warm needling group and a western medication group, 40 cases in each one. In the long-snake moxibustion group, the long-snake moxibustion was used. The ginger-isolated moxibustion was applied along the governor vessel, from Dazhui (GV 14) to Yaoshu (GV 2), once a month, for 2 months. In the warm needling group, the main points included Dazhui (GV 14), Ganshu (BL 18), Pishu (BL 20), Shenshu (BL 23), Zhiyang (GV 9), Mingmen (GV 4) and Yaoyangguan (GV 3). The warm needling technique was used at 4 to 5 points each time, and 3 moxa cones were required at each points. The treatment was given once every two days, for 2 months. In the western medication group, methotrexate was prescribed for oral administration, 10 mg each time, once a week. If the joint pain score or joint swelling score was up to 6, diclofenac sodium was combined, 25 mg each time, 3 times a day, for 2 months. The symptom score, physical sign score, the visual analogue scale (VAS) score, levels of rheumatoid factor (RF), erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), immunoglobulin M (IgM) and immunoglobulin G (IgG) were observed before and after treatment in the patients of the three groups. RESULTS: The treatments relieved the symptoms and physical signs of rheumatoid arthritis and improved VAS score and the levels of serum RF, ESR, CRP, IgM and IgG in all of the three groups (all P<0.01). The efficacy in the long-snake moxibustion group was significantly better than that in the warm needling group and the western medication group (P<0.05, P<0.01). CONCLUSIONS: The long-snake moxibustion achieves the significant clinical efficacy on rheumatoid arthritis, better than warm needling therapy and methotrexate. This therapy much better reduces immune response and alleviates the sickness. SN - 0255-2930 UR - https://www.unboundmedicine.com/medline/citation/29231407/[Long_snake_moxibustion_for_rheumatoid_arthritis:a_randomized_controlled_trial]_ L2 - http://www.diseaseinfosearch.org/result/592 DB - PRIME DP - Unbound Medicine ER -