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[Prescription regularity of famous veteran traditional Chinese medicine Doctor Yu Guoyou for treating gastrointestinal failure based ondata mining].
Zhongguo Zhong Yao Za Zhi 2017; 42(19):3809-3814ZZ

Abstract

Gastrointestinal failure is a kind of severe systemic inflammatory response, and often complicated with multiple organ dysfunction syndrome. Integrated traditional Chinese and Western medicine have a better curative effect in treating it. This study collected the famous veteran TCM physician Yu Guoyou's 175 prescriptions for treating 89 cases of gastrointestinal failure, calculated the frequency of traditional Chinese medicines and their categories, and analyzed the medication regularity with system clustering method, so as to summarize Yu's frequently used drugs and prescriptions. The results showed the top three most frequently used drugs aremagnolia bark, bitter orange, and rhubarb, which are components of Xiaochengqi decoction; Among the traditional Chinese medicines, medicines of tonifying deficiency, regulating qi, clearing heat, eliminating phlegm and dissipating dampness are most commonly used. Among the tonic medicines, those for tonifying Qi accounted for 2/3, which was the largest proportion; At the same time, some new prescriptions and new drug combinations were excavated and could be used as the reference for clinical medication. According to the findings, when differentiating syndromes of gastrointestinal failure, Yu regards the spleen and stomach Qi deficiency as the root cause and the heat toxin, blood stasis, Qi stagnation and dampness as the symptoms. In the treatment of gastrointestinal function failure, Yu gives priority to strengthening spleen, regulating Qi and purgation, prescribes medicines for dissolving blood stasis and detoxication, dissipating dampness, clearing heat and eliminating phlegm according to syndrome types. In other words, the treatment is based on syndrome differentiation, and the prescription is modified according to symptoms. In particular, Yu attaches importance to stomach-Qi recuperation and gastrointestinal function recovery in the process of treatment.

Authors+Show Affiliations

The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China.Zhejiang University of Traditional Chinese Medicine, Hangzhou 310053, China.The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China.The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China.The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China.

Pub Type(s)

Journal Article

Language

chi

PubMed ID

29235299

Citation

Wang, Qing, et al. "[Prescription Regularity of Famous Veteran Traditional Chinese Medicine Doctor Yu Guoyou for Treating Gastrointestinal Failure Based Ondata Mining]." Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, vol. 42, no. 19, 2017, pp. 3809-3814.
Wang Q, Chen YL, Wu GL, et al. [Prescription regularity of famous veteran traditional Chinese medicine Doctor Yu Guoyou for treating gastrointestinal failure based ondata mining]. Zhongguo Zhong Yao Za Zhi. 2017;42(19):3809-3814.
Wang, Q., Chen, Y. L., Wu, G. L., Xiong, F. L., & Yu, G. Y. (2017). [Prescription regularity of famous veteran traditional Chinese medicine Doctor Yu Guoyou for treating gastrointestinal failure based ondata mining]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, 42(19), pp. 3809-3814. doi:10.19540/j.cnki.cjcmm.20170901.003.
Wang Q, et al. [Prescription Regularity of Famous Veteran Traditional Chinese Medicine Doctor Yu Guoyou for Treating Gastrointestinal Failure Based Ondata Mining]. Zhongguo Zhong Yao Za Zhi. 2017;42(19):3809-3814. PubMed PMID: 29235299.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Prescription regularity of famous veteran traditional Chinese medicine Doctor Yu Guoyou for treating gastrointestinal failure based ondata mining]. AU - Wang,Qing, AU - Chen,Yi-Lian, AU - Wu,Guo-Lin, AU - Xiong,Fu-Lin, AU - Yu,Guo-You, PY - 2017/05/11/received PY - 2017/12/14/entrez PY - 2017/12/14/pubmed PY - 2017/12/14/medline KW - Yu Guoyou KW - clustering KW - data mining KW - gastrointestinal function failure KW - prescription regularity KW - traditional Chinese medicine SP - 3809 EP - 3814 JF - Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica JO - Zhongguo Zhong Yao Za Zhi VL - 42 IS - 19 N2 - Gastrointestinal failure is a kind of severe systemic inflammatory response, and often complicated with multiple organ dysfunction syndrome. Integrated traditional Chinese and Western medicine have a better curative effect in treating it. This study collected the famous veteran TCM physician Yu Guoyou's 175 prescriptions for treating 89 cases of gastrointestinal failure, calculated the frequency of traditional Chinese medicines and their categories, and analyzed the medication regularity with system clustering method, so as to summarize Yu's frequently used drugs and prescriptions. The results showed the top three most frequently used drugs aremagnolia bark, bitter orange, and rhubarb, which are components of Xiaochengqi decoction; Among the traditional Chinese medicines, medicines of tonifying deficiency, regulating qi, clearing heat, eliminating phlegm and dissipating dampness are most commonly used. Among the tonic medicines, those for tonifying Qi accounted for 2/3, which was the largest proportion; At the same time, some new prescriptions and new drug combinations were excavated and could be used as the reference for clinical medication. According to the findings, when differentiating syndromes of gastrointestinal failure, Yu regards the spleen and stomach Qi deficiency as the root cause and the heat toxin, blood stasis, Qi stagnation and dampness as the symptoms. In the treatment of gastrointestinal function failure, Yu gives priority to strengthening spleen, regulating Qi and purgation, prescribes medicines for dissolving blood stasis and detoxication, dissipating dampness, clearing heat and eliminating phlegm according to syndrome types. In other words, the treatment is based on syndrome differentiation, and the prescription is modified according to symptoms. In particular, Yu attaches importance to stomach-Qi recuperation and gastrointestinal function recovery in the process of treatment. SN - 1001-5302 UR - https://www.unboundmedicine.com/medline/citation/29235299/[Prescription_regularity_of_famous_veteran_traditional_Chinese_medicine_Doctor_Yu_Guoyou_for_treating_gastrointestinal_failure_based_ondata_mining] DB - PRIME DP - Unbound Medicine ER -