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A review of monochromatic light devices for the treatment of alopecia areata.
Lasers Med Sci. 2018 Feb; 33(2):435-444.LM

Abstract

There are many laser technologies that are being tested that claim to support hair regrowth for patients with alopecia areata (AA). In this paper, we will determine whether the body of evidence supports the use of devices using monochromatic light sources to treat AA. Articles were gathered from PubMed, Embase, and the Cochrane database using these keywords: lasers, excimer laser, low-level laser therapy (LLLT), low-level light therapy, alopecia, alopecia areata, and hair loss with a category modifier of English. Ten clinical trials and seven case reports/abstracts were assessed. Eight clinical trials and two case reports demonstrated hair regrowth with the 308-nm excimer laser/light in men, women, and children. One case report demonstrated hair regrowth with the ALBA 355® laser. One clinical trial and two case reports demonstrated hair regrowth with LLLT. While two case reports demonstrated hair regrowth with fractional laser therapy, one clinical trial showed no improvement. The 308-nm excimer laser is a safe and effective treatment for men, women, and children with refractory AA of the scalp and beard. Larger, double-blinded clinical trials should be conducted to compare excimer laser therapy to standard treatments. More data is needed to determine the efficacy of LLLT and fractional laser therapy in the treatment of AA.

Authors+Show Affiliations

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1600 NW 10th Ave., RMSB 2023, Miami, FL, 33136, USA. exd166@med.miami.edu.Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1600 NW 10th Ave., RMSB 2023, Miami, FL, 33136, USA.Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1600 NW 10th Ave., RMSB 2023, Miami, FL, 33136, USA.Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1600 NW 10th Ave., RMSB 2023, Miami, FL, 33136, USA.Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1600 NW 10th Ave., RMSB 2023, Miami, FL, 33136, USA.

Pub Type(s)

Journal Article
Meta-Analysis
Review

Language

eng

PubMed ID

29250710

Citation

Darwin, Evan, et al. "A Review of Monochromatic Light Devices for the Treatment of Alopecia Areata." Lasers in Medical Science, vol. 33, no. 2, 2018, pp. 435-444.
Darwin E, Arora H, Hirt PA, et al. A review of monochromatic light devices for the treatment of alopecia areata. Lasers Med Sci. 2018;33(2):435-444.
Darwin, E., Arora, H., Hirt, P. A., Wikramanayake, T. C., & Jimenez, J. J. (2018). A review of monochromatic light devices for the treatment of alopecia areata. Lasers in Medical Science, 33(2), 435-444. https://doi.org/10.1007/s10103-017-2412-6
Darwin E, et al. A Review of Monochromatic Light Devices for the Treatment of Alopecia Areata. Lasers Med Sci. 2018;33(2):435-444. PubMed PMID: 29250710.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A review of monochromatic light devices for the treatment of alopecia areata. AU - Darwin,Evan, AU - Arora,Harleen, AU - Hirt,Penelope A, AU - Wikramanayake,Tongyu Cao, AU - Jimenez,Joaquin J, Y1 - 2017/12/17/ PY - 2017/05/01/received PY - 2017/12/04/accepted PY - 2017/12/19/pubmed PY - 2018/4/24/medline PY - 2017/12/19/entrez KW - Alopecia KW - Alopecia areata KW - Excimer laser KW - Lasers KW - Low-level light therapy SP - 435 EP - 444 JF - Lasers in medical science JO - Lasers Med Sci VL - 33 IS - 2 N2 - There are many laser technologies that are being tested that claim to support hair regrowth for patients with alopecia areata (AA). In this paper, we will determine whether the body of evidence supports the use of devices using monochromatic light sources to treat AA. Articles were gathered from PubMed, Embase, and the Cochrane database using these keywords: lasers, excimer laser, low-level laser therapy (LLLT), low-level light therapy, alopecia, alopecia areata, and hair loss with a category modifier of English. Ten clinical trials and seven case reports/abstracts were assessed. Eight clinical trials and two case reports demonstrated hair regrowth with the 308-nm excimer laser/light in men, women, and children. One case report demonstrated hair regrowth with the ALBA 355® laser. One clinical trial and two case reports demonstrated hair regrowth with LLLT. While two case reports demonstrated hair regrowth with fractional laser therapy, one clinical trial showed no improvement. The 308-nm excimer laser is a safe and effective treatment for men, women, and children with refractory AA of the scalp and beard. Larger, double-blinded clinical trials should be conducted to compare excimer laser therapy to standard treatments. More data is needed to determine the efficacy of LLLT and fractional laser therapy in the treatment of AA. SN - 1435-604X UR - https://www.unboundmedicine.com/medline/citation/29250710/A_review_of_monochromatic_light_devices_for_the_treatment_of_alopecia_areata_ L2 - https://dx.doi.org/10.1007/s10103-017-2412-6 DB - PRIME DP - Unbound Medicine ER -