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Gene Editing in Humans: Towards a Global and Inclusive Debate for Responsible Research.
Yale J Biol Med. 2017 12; 90(4):673-681.YJ

Abstract

In December 2016, the Opinion Group of the Bioethics and Law Observatory (OBD) of the University of Barcelona launched a Declaration on Bioethics and Gene Editing in Humans analyzing the use of genome editing techniques and their social, ethical, and legal implications through a multidisciplinary approach. It focuses on CRISPR/Cas9, a genome modification technique that enables researchers to edit specific sections of the DNA sequence of humans and other living beings. This technique has generated expectations and worries that deserve an interdisciplinary analysis and an informed social debate. The research work developed by the OBD presents a set of recommendations addressed to different stakeholders and aims at being a tool to learn more about CRISPR/Cas9 while finding an appropriate ethical and legal framework for this new technology. This article gathers and compares reports that have been published in Europe and the USA since the OBD Declaration. It aims at being a tool to foster a global and interdisciplinary discussion of this new genome editing technology.

Authors+Show Affiliations

Bioethics and Law Observatory, University of Barcelona, Barcelona, Spain.Bioethics and Law Observatory, University of Barcelona, Barcelona, Spain.Faculty of Biology, University of Barcelona, Barcelona, Spain.Bioethics and Law Observatory, University of Barcelona, Barcelona, Spain.Bioethics and Law Observatory, University of Barcelona, Barcelona, Spain.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29259532

Citation

de Lecuona, Itziar, et al. "Gene Editing in Humans: Towards a Global and Inclusive Debate for Responsible Research." The Yale Journal of Biology and Medicine, vol. 90, no. 4, 2017, pp. 673-681.
de Lecuona I, Casado M, Marfany G, et al. Gene Editing in Humans: Towards a Global and Inclusive Debate for Responsible Research. Yale J Biol Med. 2017;90(4):673-681.
de Lecuona, I., Casado, M., Marfany, G., Lopez Baroni, M., & Escarrabill, M. (2017). Gene Editing in Humans: Towards a Global and Inclusive Debate for Responsible Research. The Yale Journal of Biology and Medicine, 90(4), 673-681.
de Lecuona I, et al. Gene Editing in Humans: Towards a Global and Inclusive Debate for Responsible Research. Yale J Biol Med. 2017;90(4):673-681. PubMed PMID: 29259532.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Gene Editing in Humans: Towards a Global and Inclusive Debate for Responsible Research. AU - de Lecuona,Itziar, AU - Casado,María, AU - Marfany,Gemma, AU - Lopez Baroni,Manuel, AU - Escarrabill,Mar, Y1 - 2017/12/19/ PY - 2017/12/21/entrez PY - 2017/12/21/pubmed PY - 2018/7/20/medline KW - CRISPR KW - Ethics KW - Gene editing KW - Responsible Research SP - 673 EP - 681 JF - The Yale journal of biology and medicine JO - Yale J Biol Med VL - 90 IS - 4 N2 - In December 2016, the Opinion Group of the Bioethics and Law Observatory (OBD) of the University of Barcelona launched a Declaration on Bioethics and Gene Editing in Humans analyzing the use of genome editing techniques and their social, ethical, and legal implications through a multidisciplinary approach. It focuses on CRISPR/Cas9, a genome modification technique that enables researchers to edit specific sections of the DNA sequence of humans and other living beings. This technique has generated expectations and worries that deserve an interdisciplinary analysis and an informed social debate. The research work developed by the OBD presents a set of recommendations addressed to different stakeholders and aims at being a tool to learn more about CRISPR/Cas9 while finding an appropriate ethical and legal framework for this new technology. This article gathers and compares reports that have been published in Europe and the USA since the OBD Declaration. It aims at being a tool to foster a global and interdisciplinary discussion of this new genome editing technology. SN - 1551-4056 UR - https://www.unboundmedicine.com/medline/citation/29259532/Gene_Editing_in_Humans:_Towards_a_Global_and_Inclusive_Debate_for_Responsible_Research_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/29259532/ DB - PRIME DP - Unbound Medicine ER -