Citation
Darius, Hélène Taiana, et al. "Tectus Niloticus (Tegulidae, Gastropod) as a Novel Vector of Ciguatera Poisoning: Detection of Pacific Ciguatoxins in Toxic Samples From Nuku Hiva Island (French Polynesia)." Toxins, vol. 10, no. 1, 2017.
Darius HT, Roué M, Sibat M, et al. Tectus niloticus (Tegulidae, Gastropod) as a Novel Vector of Ciguatera Poisoning: Detection of Pacific Ciguatoxins in Toxic Samples from Nuku Hiva Island (French Polynesia). Toxins (Basel). 2017;10(1).
Darius, H. T., Roué, M., Sibat, M., Viallon, J., Gatti, C. M. I., Vandersea, M. W., Tester, P. A., Litaker, R. W., Amzil, Z., Hess, P., & Chinain, M. (2017). Tectus niloticus (Tegulidae, Gastropod) as a Novel Vector of Ciguatera Poisoning: Detection of Pacific Ciguatoxins in Toxic Samples from Nuku Hiva Island (French Polynesia). Toxins, 10(1). https://doi.org/10.3390/toxins10010002
Darius HT, et al. Tectus Niloticus (Tegulidae, Gastropod) as a Novel Vector of Ciguatera Poisoning: Detection of Pacific Ciguatoxins in Toxic Samples From Nuku Hiva Island (French Polynesia). Toxins (Basel). 2017 12 21;10(1) PubMed PMID: 29267222.
TY - JOUR
T1 - Tectus niloticus (Tegulidae, Gastropod) as a Novel Vector of Ciguatera Poisoning: Detection of Pacific Ciguatoxins in Toxic Samples from Nuku Hiva Island (French Polynesia).
AU - Darius,Hélène Taiana,
AU - Roué,Mélanie,
AU - Sibat,Manoella,
AU - Viallon,Jérôme,
AU - Gatti,Clémence Mahana Iti,
AU - Vandersea,Mark W,
AU - Tester,Patricia A,
AU - Litaker,R Wayne,
AU - Amzil,Zouher,
AU - Hess,Philipp,
AU - Chinain,Mireille,
Y1 - 2017/12/21/
PY - 2017/11/25/received
PY - 2017/12/15/revised
PY - 2017/12/18/accepted
PY - 2017/12/22/entrez
PY - 2017/12/22/pubmed
PY - 2018/12/24/medline
KW - CBA-N2a
KW - Gambierdiscus polynesiensis
KW - LC-MS/MS
KW - Tectus niloticus
KW - ciguatera poisoning
KW - ciguatoxins
KW - gastropods
KW - qPCR assays
JF - Toxins
JO - Toxins (Basel)
VL - 10
IS - 1
N2 - Ciguatera fish poisoning (CFP) is a foodborne disease caused by the consumption of seafood (fish and marine invertebrates) contaminated with ciguatoxins (CTXs) produced by dinoflagellates in the genus Gambierdiscus. The report of a CFP-like mass-poisoning outbreak following the consumption of Tectus niloticus (Tegulidae, Gastropod) from Anaho Bay on Nuku Hiva Island (Marquesas archipelago, French Polynesia) prompted field investigations to assess the presence of CTXs in T. niloticus. Samples were collected from Anaho Bay, 1, 6 and 28 months after this poisoning outbreak, as well as in Taiohae and Taipivai bays. Toxicity analysis using the neuroblastoma cell-based assay (CBA-N2a) detected the presence of CTXs only in Anaho Bay T. niloticus samples. This is consistent with qPCR results on window screen samples indicating the presence of Gambierdiscus communities dominated by the species G. polynesiensis in Anaho Bay. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) analyses revealed that P-CTX-3B was the major congener, followed by P-CTX-3C, P-CTX-4A and P-CTX-4B in toxic samples. Between July 2014 and November 2016, toxin content in T. niloticus progressively decreased, but was consistently above the safety limit recommended for human consumption. This study confirms for the first time T. niloticus as a novel vector of CFP in French Polynesia.
SN - 2072-6651
UR - https://www.unboundmedicine.com/medline/citation/29267222/Tectus_niloticus__Tegulidae_Gastropod__as_a_Novel_Vector_of_Ciguatera_Poisoning:_Detection_of_Pacific_Ciguatoxins_in_Toxic_Samples_from_Nuku_Hiva_Island__French_Polynesia__
DB - PRIME
DP - Unbound Medicine
ER -
