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Bilateral clear cell acanthoma of the areola and nipple: good response to topical corticosteroids.
An Bras Dermatol. 2017; 92(5 Suppl 1):27-29.AB

Abstract

Clear cell acanthoma is a rare, epidermal tumor not common in the area of the nipples; indeed, the literature describes only 8 cases, all showing unilateral presentation. We here report the first case of bilateral clear cell acanthoma with good response to topical corticosteroids.

CASE REPORT

A sixteen-year old girl presented with 2 excrescent, fleshy, and exudative tumor masses in both nipples and areola mammae. A biopsy was conducted and confirmed clear cell acanthoma histopathologically. Treatment with strong corticosteroids resulted in rapid improvement and resolution. After one year of follow-up, the patient developed atopic dermatitis.

DISCUSSION

We describe the first case of bilateral clear cell acanthoma localized in the nipple/areola that resolved with powerful corticosteroids, suggesting a reactive etiology of the lesion.

Authors+Show Affiliations

Department of Dermatology, Hospital Clínico San Carlos - Madrid, Spain.Department of Gynecologist and Obstetrics. Hospital Clínico San Carlos - Madrid, Spain.Department of Dermatology, Hospital Clínico San Carlos - Madrid, Spain.Department of Dermatology, Hospital Clínico San Carlos - Madrid, Spain.Department of Pathological Anatomy, Hospital Clínico San Carlos - Madrid, Spain.Department of Dermatology, Hospital Clínico San Carlos - Madrid, Spain.

Pub Type(s)

Case Reports

Language

eng

PubMed ID

29267438

Citation

González-Guerra, Elena, et al. "Bilateral Clear Cell Acanthoma of the Areola and Nipple: Good Response to Topical Corticosteroids." Anais Brasileiros De Dermatologia, vol. 92, no. 5 Suppl 1, 2017, pp. 27-29.
González-Guerra E, Rodriguez JR, Casado AF, et al. Bilateral clear cell acanthoma of the areola and nipple: good response to topical corticosteroids. An Bras Dermatol. 2017;92(5 Suppl 1):27-29.
González-Guerra, E., Rodriguez, J. R., Casado, A. F., Taboada, A. C., Toro, J. A. C., & Bran, E. L. (2017). Bilateral clear cell acanthoma of the areola and nipple: good response to topical corticosteroids. Anais Brasileiros De Dermatologia, 92(5 Suppl 1), 27-29. https://doi.org/10.1590/abd1806-4841.20175683
González-Guerra E, et al. Bilateral Clear Cell Acanthoma of the Areola and Nipple: Good Response to Topical Corticosteroids. An Bras Dermatol. 2017;92(5 Suppl 1):27-29. PubMed PMID: 29267438.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Bilateral clear cell acanthoma of the areola and nipple: good response to topical corticosteroids. AU - González-Guerra,Elena, AU - Rodriguez,Jorge Ruiz, AU - Casado,Alejandro Fueyo, AU - Taboada,Alberto Conde, AU - Toro,Jose Antonio Cortes, AU - Bran,Eduardo Lopez, PY - 2016/02/09/received PY - 2016/08/09/accepted PY - 2017/12/22/entrez PY - 2017/12/22/pubmed PY - 2018/3/29/medline SP - 27 EP - 29 JF - Anais brasileiros de dermatologia JO - An Bras Dermatol VL - 92 IS - 5 Suppl 1 N2 - : Clear cell acanthoma is a rare, epidermal tumor not common in the area of the nipples; indeed, the literature describes only 8 cases, all showing unilateral presentation. We here report the first case of bilateral clear cell acanthoma with good response to topical corticosteroids. CASE REPORT: A sixteen-year old girl presented with 2 excrescent, fleshy, and exudative tumor masses in both nipples and areola mammae. A biopsy was conducted and confirmed clear cell acanthoma histopathologically. Treatment with strong corticosteroids resulted in rapid improvement and resolution. After one year of follow-up, the patient developed atopic dermatitis. DISCUSSION: We describe the first case of bilateral clear cell acanthoma localized in the nipple/areola that resolved with powerful corticosteroids, suggesting a reactive etiology of the lesion. SN - 1806-4841 UR - https://www.unboundmedicine.com/medline/citation/29267438/Bilateral_clear_cell_acanthoma_of_the_areola_and_nipple:_good_response_to_topical_corticosteroids_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/29267438/ DB - PRIME DP - Unbound Medicine ER -