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Hyperpigmentation as a peculiar presentation of mycosis fungoides.
An Bras Dermatol. 2017; 92(5 Suppl 1):92-94.AB

Abstract

Hyperpigmented mycosis fungoides is an extremely rare subtype of mycosis fungoides. It presents as multiple pigmented macules and patches without poikilodermatous changes and characterized by a CD8+ phenotype on immunohistochemistry. This report describes a typical case of hyperpigmented mycosis fungoides in a 62-year-old woman, who presented with a 7-year history of multiple hyperpigmented macules and patches on the trunk and right leg with progression over this half a year. Histology and immunohistochemical staining of skin samples confirmed the diagnosis of mycosis fungoides. She received psoralen plus ultraviolet A (PUVA) therapy. After an 8-week treatment, the erythematous changes cleared without recurrence during a 6-month follow-up period. An intractable hyperpigmented patch should raise the clinical suspicion of mycosis fungoides with sequential skin biopsy.

Authors+Show Affiliations

Department of Dermatology, Kaohsiung Veterans General Hospital - Kaohsiung, Taiwan. Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University - Kaohsiung, Taiwan. Department of Cosmetic Applications and Management, Yuh-Ing Junior College of Health Care & Management - Kaohsiung, Taiwan.Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University - Kaohsiung, Taiwan. Division of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital - Kaohsiung, Taiwan. Department of Surgery, School of Medicine, College of Medicine, Kaohsiung Medical University - Kaohsiung, Taiwan.Department of Orthopedics, Taipei Veterans General Hospital - Taipei, Taiwan.Department of Dermatology, Kaohsiung Veterans General Hospital - Kaohsiung, Taiwan. Department of Dermatology, National Yang-Ming University, College of Medicine - Taipei, Taiwan.

Pub Type(s)

Case Reports

Language

eng

PubMed ID

29267458

Citation

Lu, Ying-Yi, et al. "Hyperpigmentation as a Peculiar Presentation of Mycosis Fungoides." Anais Brasileiros De Dermatologia, vol. 92, no. 5 Suppl 1, 2017, pp. 92-94.
Lu YY, Wu CH, Lu CC, et al. Hyperpigmentation as a peculiar presentation of mycosis fungoides. An Bras Dermatol. 2017;92(5 Suppl 1):92-94.
Lu, Y. Y., Wu, C. H., Lu, C. C., & Hong, C. H. (2017). Hyperpigmentation as a peculiar presentation of mycosis fungoides. Anais Brasileiros De Dermatologia, 92(5 Suppl 1), 92-94. https://doi.org/10.1590/abd1806-4841.20175544
Lu YY, et al. Hyperpigmentation as a Peculiar Presentation of Mycosis Fungoides. An Bras Dermatol. 2017;92(5 Suppl 1):92-94. PubMed PMID: 29267458.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hyperpigmentation as a peculiar presentation of mycosis fungoides. AU - Lu,Ying-Yi, AU - Wu,Chieh-Hsin, AU - Lu,Chun-Ching, AU - Hong,Chien-Hui, PY - 2016/01/05/received PY - 2016/04/16/accepted PY - 2017/12/22/entrez PY - 2017/12/22/pubmed PY - 2018/3/17/medline SP - 92 EP - 94 JF - Anais brasileiros de dermatologia JO - An Bras Dermatol VL - 92 IS - 5 Suppl 1 N2 - Hyperpigmented mycosis fungoides is an extremely rare subtype of mycosis fungoides. It presents as multiple pigmented macules and patches without poikilodermatous changes and characterized by a CD8+ phenotype on immunohistochemistry. This report describes a typical case of hyperpigmented mycosis fungoides in a 62-year-old woman, who presented with a 7-year history of multiple hyperpigmented macules and patches on the trunk and right leg with progression over this half a year. Histology and immunohistochemical staining of skin samples confirmed the diagnosis of mycosis fungoides. She received psoralen plus ultraviolet A (PUVA) therapy. After an 8-week treatment, the erythematous changes cleared without recurrence during a 6-month follow-up period. An intractable hyperpigmented patch should raise the clinical suspicion of mycosis fungoides with sequential skin biopsy. SN - 1806-4841 UR - https://www.unboundmedicine.com/medline/citation/29267458/Hyperpigmentation_as_a_peculiar_presentation_of_mycosis_fungoides_ DB - PRIME DP - Unbound Medicine ER -