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Quantitative Mineralogical Composition of Calculi and Urine Abnormalities for Calcium Oxalate Stone Formers: A Single-Center Results.
Urol J 2018; 15(3):87-91UJ

Abstract

PURPOSE

The paper focuses on the relationship of risk factors and metabolic disorders with mineralogical composition of calculi, age and gender of calcium oxalate stone formers.

MATERIALS AND METHODS

Stone mineralogical composition, 24 hour biochemistry and pH-profile of urine were examined for sixty four stone formers using powder X-ray diffraction, spectrophotometric and potentiometric techniques.

RESULTS

The analysis indicated that 44 % of calculi were composed of pure calcium oxalate monohydrate, whereas other 56 % contained both monohydrate and dihydrate or usually their mixtures with hydroxyl apatite. Hypocitraturia, hypercalciuria and hyperuricosuria were identified as the most frequent disorders. Patients with pure calcium oxalate stones and calcium oxalate mixed with apatite revealed different patterns including age, acid-base balance of urine, calcium, citrate excretion etc.Conclusions: Our results demonstrate that most patients simultaneously reveal several risk factors. The special attention should be paid to normalize the daily citrate, calcium and urate excretion. High risk patients, such as postmenopausal females or stone formers with a high apatite content require a specific metabolic evaluation towards in highlighting abnormalities associated with stone formation.

Authors+Show Affiliations

Ivanovo State Medical Academy, 153012 Ivanovo, Russian Federation. kustov@isuct.ru.Ivanovo State Medical Academy, 153012 Ivanovo, Russian Federation.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29277881

Citation

Kustov, Andrey V., and Alexander I. Strelnikov. "Quantitative Mineralogical Composition of Calculi and Urine Abnormalities for Calcium Oxalate Stone Formers: a Single-Center Results." Urology Journal, vol. 15, no. 3, 2018, pp. 87-91.
Kustov AV, Strelnikov AI. Quantitative Mineralogical Composition of Calculi and Urine Abnormalities for Calcium Oxalate Stone Formers: A Single-Center Results. Urol J. 2018;15(3):87-91.
Kustov, A. V., & Strelnikov, A. I. (2018). Quantitative Mineralogical Composition of Calculi and Urine Abnormalities for Calcium Oxalate Stone Formers: A Single-Center Results. Urology Journal, 15(3), pp. 87-91. doi:10.22037/uj.v0i0.3910.
Kustov AV, Strelnikov AI. Quantitative Mineralogical Composition of Calculi and Urine Abnormalities for Calcium Oxalate Stone Formers: a Single-Center Results. Urol J. 2018 05 3;15(3):87-91. PubMed PMID: 29277881.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Quantitative Mineralogical Composition of Calculi and Urine Abnormalities for Calcium Oxalate Stone Formers: A Single-Center Results. AU - Kustov,Andrey V, AU - Strelnikov,Alexander I, Y1 - 2018/05/03/ PY - 2017/12/27/pubmed PY - 2018/11/14/medline PY - 2017/12/27/entrez SP - 87 EP - 91 JF - Urology journal JO - Urol J VL - 15 IS - 3 N2 - PURPOSE: The paper focuses on the relationship of risk factors and metabolic disorders with mineralogical composition of calculi, age and gender of calcium oxalate stone formers. MATERIALS AND METHODS: Stone mineralogical composition, 24 hour biochemistry and pH-profile of urine were examined for sixty four stone formers using powder X-ray diffraction, spectrophotometric and potentiometric techniques. RESULTS: The analysis indicated that 44 % of calculi were composed of pure calcium oxalate monohydrate, whereas other 56 % contained both monohydrate and dihydrate or usually their mixtures with hydroxyl apatite. Hypocitraturia, hypercalciuria and hyperuricosuria were identified as the most frequent disorders. Patients with pure calcium oxalate stones and calcium oxalate mixed with apatite revealed different patterns including age, acid-base balance of urine, calcium, citrate excretion etc.Conclusions: Our results demonstrate that most patients simultaneously reveal several risk factors. The special attention should be paid to normalize the daily citrate, calcium and urate excretion. High risk patients, such as postmenopausal females or stone formers with a high apatite content require a specific metabolic evaluation towards in highlighting abnormalities associated with stone formation. SN - 1735-546X UR - https://www.unboundmedicine.com/medline/citation/29277881/Quantitative_Mineralogical_Composition_of_Calculi_and_Urine_Abnormalities_for_Calcium_Oxalate_Stone_Formers:_A_Single_Center_Results_ L2 - http://journals.sbmu.ac.ir/urolj/index.php/uj/article/view/3910/1178 DB - PRIME DP - Unbound Medicine ER -