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Evaluation of the influence of kyphosis and scoliosis on intervertebral disc extrusion in French bulldogs.
BMC Vet Res. 2018 Jan 05; 14(1):5.BV

Abstract

BACKGROUND

Although thoracic vertebral malformations with kyphosis and scoliosis are often considered incidental findings on diagnostic imaging studies of screw-tailed brachycephalic breeds, they have been suggested to interfere with spinal biomechanics and intervertebral disc degeneration. It is however unknown if an abnormal spinal curvature also predisposes dogs to develop clinically relevant intervertebral disc herniations. The aim of this study was to evaluate if the occurrence of thoracic vertebral malformations, kyphosis or scoliosis would be associated with a higher prevalence of cervical or thoracolumbar intervertebral disc extrusion in French bulldogs.

RESULTS

French bulldogs that underwent computed tomography for reasons unrelated to spinal disease (n = 101), and French bulldogs with thoracolumbar (n = 47) or cervical intervertebral disc extrusion (n = 30) that underwent magnetic resonance imaging were included. There was a significant association between the presence of kyphosis and the occurrence of intervertebral disc extrusion, particularly in the thoracolumbar region. Dogs with kyphosis were at nearly a two times increased odds of being affected by intervertebral disc extrusion than those without kyphosis [(OR = 1.98 (95% CI: 1.04-3.78)]. There was also an association between the presence of scoliosis and the anatomical distribution of intervertebral disc extrusions, with dogs with scoliosis more likely to have more caudal lumbar intervertebral disc extrusions. Presence of scoliosis was not associated with an increased odds of being affected by intervertebral disc extrusion.

CONCLUSIONS

Although thoracic vertebral malformations with kyphosis only rarely cause spinal cord dysfunction in itself, French bulldogs with kyphosis appear to be at higher risk to develop thoracolumbar intervertebral disc extrusion.

Authors+Show Affiliations

Department of Surgery, University of São Paulo-School of Veterinary Medicine and Animal Science, Av. Prof. Dr. Orlando Marques de Paiva, 87, São Paulo, Cidade Universitária, Brazil. Department of Clinical Science and Services, Royal Veterinary College, University of London, Hawkshead lane, AL9 7TA North Mymms, Hatfield, UK.Department of Clinical Science and Services, Royal Veterinary College, University of London, Hawkshead lane, AL9 7TA North Mymms, Hatfield, UK.Department of Clinical Science and Services, Royal Veterinary College, University of London, Hawkshead lane, AL9 7TA North Mymms, Hatfield, UK.Department of Clinical Science and Services, Royal Veterinary College, University of London, Hawkshead lane, AL9 7TA North Mymms, Hatfield, UK.Department of Clinical Science and Services, Royal Veterinary College, University of London, Hawkshead lane, AL9 7TA North Mymms, Hatfield, UK.Department of Clinical Science and Services, Royal Veterinary College, University of London, Hawkshead lane, AL9 7TA North Mymms, Hatfield, UK. sdedecker@rvc.ac.uk.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29304802

Citation

Inglez de Souza, Maria Claudia C M., et al. "Evaluation of the Influence of Kyphosis and Scoliosis On Intervertebral Disc Extrusion in French Bulldogs." BMC Veterinary Research, vol. 14, no. 1, 2018, p. 5.
Inglez de Souza MCCM, Ryan R, Ter Haar G, et al. Evaluation of the influence of kyphosis and scoliosis on intervertebral disc extrusion in French bulldogs. BMC Vet Res. 2018;14(1):5.
Inglez de Souza, M. C. C. M., Ryan, R., Ter Haar, G., Packer, R. M. A., Volk, H. A., & De Decker, S. (2018). Evaluation of the influence of kyphosis and scoliosis on intervertebral disc extrusion in French bulldogs. BMC Veterinary Research, 14(1), 5. https://doi.org/10.1186/s12917-017-1316-9
Inglez de Souza MCCM, et al. Evaluation of the Influence of Kyphosis and Scoliosis On Intervertebral Disc Extrusion in French Bulldogs. BMC Vet Res. 2018 Jan 5;14(1):5. PubMed PMID: 29304802.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of the influence of kyphosis and scoliosis on intervertebral disc extrusion in French bulldogs. AU - Inglez de Souza,Maria Claudia C M, AU - Ryan,Richard, AU - Ter Haar,Gert, AU - Packer,Rowena M A, AU - Volk,Holger A, AU - De Decker,Steven, Y1 - 2018/01/05/ PY - 2017/01/30/received PY - 2017/12/08/accepted PY - 2018/1/7/entrez PY - 2018/1/7/pubmed PY - 2018/9/18/medline KW - Brachycephalic KW - Hemivertebra KW - Intervertebral disc disease KW - Intervertebral disc herniation KW - Vertebral malformation SP - 5 EP - 5 JF - BMC veterinary research JO - BMC Vet. Res. VL - 14 IS - 1 N2 - BACKGROUND: Although thoracic vertebral malformations with kyphosis and scoliosis are often considered incidental findings on diagnostic imaging studies of screw-tailed brachycephalic breeds, they have been suggested to interfere with spinal biomechanics and intervertebral disc degeneration. It is however unknown if an abnormal spinal curvature also predisposes dogs to develop clinically relevant intervertebral disc herniations. The aim of this study was to evaluate if the occurrence of thoracic vertebral malformations, kyphosis or scoliosis would be associated with a higher prevalence of cervical or thoracolumbar intervertebral disc extrusion in French bulldogs. RESULTS: French bulldogs that underwent computed tomography for reasons unrelated to spinal disease (n = 101), and French bulldogs with thoracolumbar (n = 47) or cervical intervertebral disc extrusion (n = 30) that underwent magnetic resonance imaging were included. There was a significant association between the presence of kyphosis and the occurrence of intervertebral disc extrusion, particularly in the thoracolumbar region. Dogs with kyphosis were at nearly a two times increased odds of being affected by intervertebral disc extrusion than those without kyphosis [(OR = 1.98 (95% CI: 1.04-3.78)]. There was also an association between the presence of scoliosis and the anatomical distribution of intervertebral disc extrusions, with dogs with scoliosis more likely to have more caudal lumbar intervertebral disc extrusions. Presence of scoliosis was not associated with an increased odds of being affected by intervertebral disc extrusion. CONCLUSIONS: Although thoracic vertebral malformations with kyphosis only rarely cause spinal cord dysfunction in itself, French bulldogs with kyphosis appear to be at higher risk to develop thoracolumbar intervertebral disc extrusion. SN - 1746-6148 UR - https://www.unboundmedicine.com/medline/citation/29304802/Evaluation_of_the_influence_of_kyphosis_and_scoliosis_on_intervertebral_disc_extrusion_in_French_bulldogs_ L2 - https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-017-1316-9 DB - PRIME DP - Unbound Medicine ER -