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Wernicke encephalopathy in a patient after liver transplantation: A case report.
World J Gastroenterol. 2017 Dec 21; 23(47):8432-8436.WJ

Abstract

Wernicke encephalopathy (WE) is an acute neurological disorder resulting from vitamin B1 deficiency, which is common in chronic alcoholism and is rare in acute liver failure. So far, there are 2 cases of WE reported after liver transplantation. Here, we report a case of a 45-year-old nonalcoholic male patient who developed psychiatric and neurological disturbance 15 d after receiving orthotopic liver transplantation because of hepatitis B-related cirrhosis and portal hypertension. Brain magnetic resonance imaging (MRI) showed symmetric high-signal intensities in the periaqueductal area. The patient was diagnosed with WE and given intravenous high-dose vitamin B1 immediately. His neurological disturbance resolved in 7 d after receiving the vitamin B1. Brain MRI after 5 mo showed nearly complete recovery. Most WE cases may be misdiagnosed in patients after liver transplantation, and we should pay more attention to its onset.

Authors+Show Affiliations

Organ Transplantation Center, The Second Xiang-ya Hospital, Central South University, Changsha 410011, Hunan Province, China.Organ Transplantation Center, The Second Xiang-ya Hospital, Central South University, Changsha 410011, Hunan Province, China.Department of Neurology, Xiang-ya Hospital, Central South University, Changsha 410008, Hunan Province, China.Organ Transplantation Center, The Second Xiang-ya Hospital, Central South University, Changsha 410011, Hunan Province, China.Organ Transplantation Center, The Second Xiang-ya Hospital, Central South University, Changsha 410011, Hunan Province, China. liting001@csu.edu.cn.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

29308003

Citation

Xie, Bin, et al. "Wernicke Encephalopathy in a Patient After Liver Transplantation: a Case Report." World Journal of Gastroenterology, vol. 23, no. 47, 2017, pp. 8432-8436.
Xie B, Si ZZ, Tang WT, et al. Wernicke encephalopathy in a patient after liver transplantation: A case report. World J Gastroenterol. 2017;23(47):8432-8436.
Xie, B., Si, Z. Z., Tang, W. T., Qi, H. Z., & Li, T. (2017). Wernicke encephalopathy in a patient after liver transplantation: A case report. World Journal of Gastroenterology, 23(47), 8432-8436. https://doi.org/10.3748/wjg.v23.i47.8432
Xie B, et al. Wernicke Encephalopathy in a Patient After Liver Transplantation: a Case Report. World J Gastroenterol. 2017 Dec 21;23(47):8432-8436. PubMed PMID: 29308003.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Wernicke encephalopathy in a patient after liver transplantation: A case report. AU - Xie,Bin, AU - Si,Zhong-Zhou, AU - Tang,Wei-Ting, AU - Qi,Hai-Zhi, AU - Li,Ting, PY - 2017/10/20/received PY - 2017/11/22/revised PY - 2017/11/27/accepted PY - 2018/1/9/entrez PY - 2018/1/9/pubmed PY - 2018/8/9/medline KW - Liver transplantation KW - Magnetic resonance imaging KW - Pharmacotherapy KW - Prevention KW - Thiamine deficiency KW - Wernicke encephalopathy SP - 8432 EP - 8436 JF - World journal of gastroenterology JO - World J Gastroenterol VL - 23 IS - 47 N2 - Wernicke encephalopathy (WE) is an acute neurological disorder resulting from vitamin B1 deficiency, which is common in chronic alcoholism and is rare in acute liver failure. So far, there are 2 cases of WE reported after liver transplantation. Here, we report a case of a 45-year-old nonalcoholic male patient who developed psychiatric and neurological disturbance 15 d after receiving orthotopic liver transplantation because of hepatitis B-related cirrhosis and portal hypertension. Brain magnetic resonance imaging (MRI) showed symmetric high-signal intensities in the periaqueductal area. The patient was diagnosed with WE and given intravenous high-dose vitamin B1 immediately. His neurological disturbance resolved in 7 d after receiving the vitamin B1. Brain MRI after 5 mo showed nearly complete recovery. Most WE cases may be misdiagnosed in patients after liver transplantation, and we should pay more attention to its onset. SN - 2219-2840 UR - https://www.unboundmedicine.com/medline/citation/29308003/Wernicke_encephalopathy_in_a_patient_after_liver_transplantation:_A_case_report_ DB - PRIME DP - Unbound Medicine ER -