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Solitary extramedullary plasmacytoma of the duodenum and pancreas: A case report and review of the literature.
Vojnosanit Pregl. 2016 Apr; 73(4):402-7.VP

Abstract

Introduction

The extramedullary plasmacytomas (EMPs) are rare tumors of plasma cell disorders which are rarely found in the duodenum. We presented a case of solitary EMPs involving the duodenum and pancreas successfully treated by surgical resection after failure of chemotherapy.

Case Report

A 55-year-old female with previously diagnosed solitary EMP of the duodenum was admitted to our institution after failure of three cycles of vincristine, adriablastine, dexamethasone (VAD) chemotherapy regimen with an upper gastrointestinal obstruction. On admission computed tomography of the abdomen showed tumor in the region of the second part of duodenum and uncinate process of the pancreas with a complete duodenal obstruction. Intraoperatively a tumor formation was in the region of the second duodenal part, originated from the wall of duodenum with the total diameter of 7 x 5 cm, covering the entire circumference of duodenal wall leaded to a narrowing of duodenal lumen to the thigh gap with an upper gastrointestinal obstruction. Infiltration in the head of the pancreas and uncinate process were also found. The Whipple’s procedure was performed but postoperative course was complicated by rapidly refilling chylous ascites which was resolved 4 days after the surgery.

Conclusion

Each patient with gastrointestinal EMPs should be considered separately and in timely manner, thus adequate treatment could provide local disease control.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

29309111

Citation

Ignjatović, Mile, et al. "Solitary Extramedullary Plasmacytoma of the Duodenum and Pancreas: a Case Report and Review of the Literature." Vojnosanitetski Pregled, vol. 73, no. 4, 2016, pp. 402-7.
Ignjatović M, Bezmarević M, Cerović S. Solitary extramedullary plasmacytoma of the duodenum and pancreas: A case report and review of the literature. Vojnosanit Pregl. 2016;73(4):402-7.
Ignjatović, M., Bezmarević, M., & Cerović, S. (2016). Solitary extramedullary plasmacytoma of the duodenum and pancreas: A case report and review of the literature. Vojnosanitetski Pregled, 73(4), 402-7. https://doi.org/10.2298/VSP141031142I
Ignjatović M, Bezmarević M, Cerović S. Solitary Extramedullary Plasmacytoma of the Duodenum and Pancreas: a Case Report and Review of the Literature. Vojnosanit Pregl. 2016;73(4):402-7. PubMed PMID: 29309111.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Solitary extramedullary plasmacytoma of the duodenum and pancreas: A case report and review of the literature. AU - Ignjatović,Mile, AU - Bezmarević,Mihailo, AU - Cerović,Snežana, PY - 2018/1/9/entrez PY - 2016/4/1/pubmed PY - 2018/2/14/medline SP - 402 EP - 7 JF - Vojnosanitetski pregled JO - Vojnosanit Pregl VL - 73 IS - 4 N2 - Introduction: The extramedullary plasmacytomas (EMPs) are rare tumors of plasma cell disorders which are rarely found in the duodenum. We presented a case of solitary EMPs involving the duodenum and pancreas successfully treated by surgical resection after failure of chemotherapy. Case Report: A 55-year-old female with previously diagnosed solitary EMP of the duodenum was admitted to our institution after failure of three cycles of vincristine, adriablastine, dexamethasone (VAD) chemotherapy regimen with an upper gastrointestinal obstruction. On admission computed tomography of the abdomen showed tumor in the region of the second part of duodenum and uncinate process of the pancreas with a complete duodenal obstruction. Intraoperatively a tumor formation was in the region of the second duodenal part, originated from the wall of duodenum with the total diameter of 7 x 5 cm, covering the entire circumference of duodenal wall leaded to a narrowing of duodenal lumen to the thigh gap with an upper gastrointestinal obstruction. Infiltration in the head of the pancreas and uncinate process were also found. The Whipple’s procedure was performed but postoperative course was complicated by rapidly refilling chylous ascites which was resolved 4 days after the surgery. Conclusion: Each patient with gastrointestinal EMPs should be considered separately and in timely manner, thus adequate treatment could provide local disease control. SN - 0042-8450 UR - https://www.unboundmedicine.com/medline/citation/29309111/Solitary_extramedullary_plasmacytoma_of_the_duodenum_and_pancreas:_A_case_report_and_review_of_the_literature_ L2 - https://medlineplus.gov/intestinalcancer.html DB - PRIME DP - Unbound Medicine ER -