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[Paraneoplasms of the skin].
Internist (Berl). 2018 Feb; 59(2):134-144.I

Abstract

The cutaneous manifestations of malignancies include nonmalignant skin disorders that occur in association with malignancies (facultative paraneoplastic dermatoses) and skin disorders that are always associated with hematologic diseases or solid tumors (obligate paraneoplastic dermatoses). Paraneoplastic increase of growth factors or immunological reactions lead to a variety of inflammatory, hyperkeratotic or proliferative skin reactions. When paraneoplastic dermatoses develop before cancer is diagnosed, recognition of these skin diseases can accelerate both the diagnosis and treatment. The presence of unexplained cutaneous findings should lead to a multidisciplinary evaluation of the patient. This manuscript summarizes the cutaneous manifestations associated with hematologic disorders and solid tumors, their localization and treatment options.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Gieβen-Jung C
Medizinische Klinik und Poliklinik III, Klinikum der Universität München, Ludwig-Maximilians-Universität München, Marchioninistr. 15, 81377, München, Deutschland. clemens.giessen-jung@med.uni-muenchen.de.
Wollenberg A
Klinik und Poliklinik für Dermatologie und Allergologie, Klinikum der Universität München, Ludwig-Maximilians-Universität München, München, Deutschland.
Reinholz M
Klinik und Poliklinik für Dermatologie und Allergologie, Klinikum der Universität München, Ludwig-Maximilians-Universität München, München, Deutschland.

MeSH

Acanthosis NigricansDermatomyositisDiagnosis, DifferentialExanthemaHematologic NeoplasmsHumansLeukemiaLymphomaNeoplasmsParaneoplastic SyndromesPemphigusPrognosisSkin Diseases

Pub Type(s)

Journal Article
Review

Language

ger

PubMed ID

29322218

Citation

Gieβen-Jung, C, et al. "[Paraneoplasms of the Skin]." Der Internist, vol. 59, no. 2, 2018, pp. 134-144.
Gieβen-Jung C, Wollenberg A, Reinholz M. [Paraneoplasms of the skin]. Internist (Berl). 2018;59(2):134-144.
Gieβen-Jung, C., Wollenberg, A., & Reinholz, M. (2018). [Paraneoplasms of the skin]. Der Internist, 59(2), 134-144. https://doi.org/10.1007/s00108-017-0372-3
Gieβen-Jung C, Wollenberg A, Reinholz M. [Paraneoplasms of the Skin]. Internist (Berl). 2018;59(2):134-144. PubMed PMID: 29322218.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Paraneoplasms of the skin]. AU - Gieβen-Jung,C, AU - Wollenberg,A, AU - Reinholz,M, PY - 2018/1/13/pubmed PY - 2019/5/29/medline PY - 2018/1/12/entrez KW - Acanthosis nigricans KW - Dermatomyositis KW - Exanthema KW - Hematologic neoplasms KW - Pemphigus SP - 134 EP - 144 JF - Der Internist JO - Internist (Berl) VL - 59 IS - 2 N2 - The cutaneous manifestations of malignancies include nonmalignant skin disorders that occur in association with malignancies (facultative paraneoplastic dermatoses) and skin disorders that are always associated with hematologic diseases or solid tumors (obligate paraneoplastic dermatoses). Paraneoplastic increase of growth factors or immunological reactions lead to a variety of inflammatory, hyperkeratotic or proliferative skin reactions. When paraneoplastic dermatoses develop before cancer is diagnosed, recognition of these skin diseases can accelerate both the diagnosis and treatment. The presence of unexplained cutaneous findings should lead to a multidisciplinary evaluation of the patient. This manuscript summarizes the cutaneous manifestations associated with hematologic disorders and solid tumors, their localization and treatment options. SN - 1432-1289 UR - https://www.unboundmedicine.com/medline/citation/29322218/[Paraneoplasms_of_the_skin]_ DB - PRIME DP - Unbound Medicine ER -