Citation
Wang, Bingyuan, et al. "Utility of Three Novel Insulin Resistance-related Lipid Indices for Predicting Type 2 Diabetes Mellitus Among People With Normal Fasting Glucose in Rural China." Journal of Diabetes, vol. 10, no. 8, 2018, pp. 641-652.
Wang B, Zhang M, Liu Y, et al. Utility of three novel insulin resistance-related lipid indices for predicting type 2 diabetes mellitus among people with normal fasting glucose in rural China. J Diabetes. 2018;10(8):641-652.
Wang, B., Zhang, M., Liu, Y., Sun, X., Zhang, L., Wang, C., Li, L., Ren, Y., Han, C., Zhao, Y., Zhou, J., Pang, C., Yin, L., Feng, T., Zhao, J., & Hu, D. (2018). Utility of three novel insulin resistance-related lipid indices for predicting type 2 diabetes mellitus among people with normal fasting glucose in rural China. Journal of Diabetes, 10(8), 641-652. https://doi.org/10.1111/1753-0407.12642
Wang B, et al. Utility of Three Novel Insulin Resistance-related Lipid Indices for Predicting Type 2 Diabetes Mellitus Among People With Normal Fasting Glucose in Rural China. J Diabetes. 2018;10(8):641-652. PubMed PMID: 29322661.
TY - JOUR
T1 - Utility of three novel insulin resistance-related lipid indices for predicting type 2 diabetes mellitus among people with normal fasting glucose in rural China.
AU - Wang,Bingyuan,
AU - Zhang,Ming,
AU - Liu,Yu,
AU - Sun,Xizhuo,
AU - Zhang,Lu,
AU - Wang,Chongjian,
AU - Li,Linlin,
AU - Ren,Yongcheng,
AU - Han,Chengyi,
AU - Zhao,Yang,
AU - Zhou,Junmei,
AU - Pang,Chao,
AU - Yin,Lei,
AU - Feng,Tianping,
AU - Zhao,Jingzhi,
AU - Hu,Dongsheng,
Y1 - 2018/02/09/
PY - 2017/07/10/received
PY - 2017/12/17/revised
PY - 2018/01/07/accepted
PY - 2018/1/13/pubmed
PY - 2018/12/12/medline
PY - 2018/1/12/entrez
KW - cohort study
KW - diabetes
KW - fat accumulation
KW - insulin resistance
KW - lipid index
KW - 糖尿病
KW - 胰岛素抵抗
KW - 脂肪堆积
KW - 血脂指数
KW - 队列研究
SP - 641
EP - 652
JF - Journal of diabetes
JO - J Diabetes
VL - 10
IS - 8
N2 - BACKGROUND: Inexpensive and easily measured indices are needed for the early prediction of type 2 diabetes mellitus (T2DM) in rural areas of China. The aim of this study was to compare triglyceride glucose (TyG), visceral adiposity (VAI), and lipid accumulation product (LAP) with traditional individual measures and their ratios for predicting T2DM. METHODS: Data for 11 113 people with baseline normal fasting glucose in a rural Chinese cohort were followed for a median of 6.0 years. Cox proportional hazards regression was used to calculate covariate-adjusted hazard ratios (aHRs) and 95% confidence intervals (95% CIs) and receiver operating characteristic analysis was used to compare the ability of traditional measures and TyG, VAI, and LAP at baseline to predict T2DM at follow-up. RESULTS: Among individual measures, fasting plasma glucose (FPG) and waist circumference (WC) were strongly associated with T2DM. Of all lipid ratios, an elevated triglycerides (TG) to high-density lipoprotein cholesterol (HDL-C) ratio was associated the most with T2DM. Compared with the first quartiles of TyG, VAI, and LAP, their fourth quartiles were associated with T2DM for men (aHR 3.54 [95% CI 2.08-6.03], 2.89 [1.72-4.87], and 5.02 [2.85-8.85], respectively) and women (6.15 [3.48-10.85], 4.40 [2.61-7.42], and 6.49 [3.48-12.12], respectively). For predicting T2DM risk, TyG, VAI, and LAP were mostly superior to the TG: HDL-C ratio, but did not differ from FPG and WC. CONCLUSIONS: Prediction of T2DM was not improved by TyG, VAI, and LAP versus FPG or WC alone. Therefore, TyG, VAI, and LAP may not be inexpensive tools for predicting T2DM in rural Chinese people.
SN - 1753-0407
UR - https://www.unboundmedicine.com/medline/citation/29322661/Utility_of_three_novel_insulin_resistance_related_lipid_indices_for_predicting_type_2_diabetes_mellitus_among_people_with_normal_fasting_glucose_in_rural_China_
L2 - https://doi.org/10.1111/1753-0407.12642
DB - PRIME
DP - Unbound Medicine
ER -