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Chemical composition and antimicrobial activity of the essential oils from flowers and leaves of Grindelia integrifolia DC.
Nat Prod Res 2019; 33(10):1535-1540NP

Abstract

Essential oils from flowers and leaves of Grindelia integrifolia DC. were investigated for the first time in terms of chemical composition and antimicrobial activity. The GC-FID/MS analysis allowed for the identification of 58 and 72 volatiles, comprising 92.4 and 90.1% of the oils, respectively. The major components of the flower oil were α-pinene (34.9%) and limonene (13.1%), while myrcene (16.9%), spathulenol (12.3%), β-eudesmol (11.9%) and limonene (10.1%) dominated among the leaf volatiles. The antimicrobial activity, evaluated against 12 selected bacteria and fungus, was found moderate, with the strongest effect of both oils observed against C. albicans (MIC = MBC: 0.63 and 0.31 mg/mL for flower and leaf oil, respectively).

Authors+Show Affiliations

a Department of Pharmacognosy , Medical University of Lodz , Lodz , Poland.b Department of Pharmaceutical Microbiology and Microbiological Diagnostics , Medical University of Lodz , Lodz , Poland.a Department of Pharmacognosy , Medical University of Lodz , Lodz , Poland.a Department of Pharmacognosy , Medical University of Lodz , Lodz , Poland.a Department of Pharmacognosy , Medical University of Lodz , Lodz , Poland.a Department of Pharmacognosy , Medical University of Lodz , Lodz , Poland.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29322829

Citation

Nowak, Sławomira, et al. "Chemical Composition and Antimicrobial Activity of the Essential Oils From Flowers and Leaves of Grindelia Integrifolia DC." Natural Product Research, vol. 33, no. 10, 2019, pp. 1535-1540.
Nowak S, Lisiecki P, Tomaszczak-Nowak A, et al. Chemical composition and antimicrobial activity of the essential oils from flowers and leaves of Grindelia integrifolia DC. Nat Prod Res. 2019;33(10):1535-1540.
Nowak, S., Lisiecki, P., Tomaszczak-Nowak, A., Grudzińska, E., Olszewska, M. A., & Kicel, A. (2019). Chemical composition and antimicrobial activity of the essential oils from flowers and leaves of Grindelia integrifolia DC. Natural Product Research, 33(10), pp. 1535-1540. doi:10.1080/14786419.2017.1423302.
Nowak S, et al. Chemical Composition and Antimicrobial Activity of the Essential Oils From Flowers and Leaves of Grindelia Integrifolia DC. Nat Prod Res. 2019;33(10):1535-1540. PubMed PMID: 29322829.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Chemical composition and antimicrobial activity of the essential oils from flowers and leaves of Grindelia integrifolia DC. AU - Nowak,Sławomira, AU - Lisiecki,Paweł, AU - Tomaszczak-Nowak,Anna, AU - Grudzińska,Ewa, AU - Olszewska,Monika Anna, AU - Kicel,Agnieszka, Y1 - 2018/01/11/ PY - 2018/1/13/pubmed PY - 2019/8/6/medline PY - 2018/1/12/entrez KW - KW - GC-FID/MS KW - antimicrobial activity KW - essential oil KW - monoterpenes KW - sesquiterpenes SP - 1535 EP - 1540 JF - Natural product research JO - Nat. Prod. Res. VL - 33 IS - 10 N2 - Essential oils from flowers and leaves of Grindelia integrifolia DC. were investigated for the first time in terms of chemical composition and antimicrobial activity. The GC-FID/MS analysis allowed for the identification of 58 and 72 volatiles, comprising 92.4 and 90.1% of the oils, respectively. The major components of the flower oil were α-pinene (34.9%) and limonene (13.1%), while myrcene (16.9%), spathulenol (12.3%), β-eudesmol (11.9%) and limonene (10.1%) dominated among the leaf volatiles. The antimicrobial activity, evaluated against 12 selected bacteria and fungus, was found moderate, with the strongest effect of both oils observed against C. albicans (MIC = MBC: 0.63 and 0.31 mg/mL for flower and leaf oil, respectively). SN - 1478-6427 UR - https://www.unboundmedicine.com/medline/citation/29322829/Chemical_composition_and_antimicrobial_activity_of_the_essential_oils_from_flowers_and_leaves_of_Grindelia_integrifolia_DC_ L2 - http://www.tandfonline.com/doi/full/10.1080/14786419.2017.1423302 DB - PRIME DP - Unbound Medicine ER -