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Dietary Carotenoid Intakes and Prostate Cancer Risk: A Case-Control Study from Vietnam.
Nutrients 2018; 10(1)N

Abstract

The incidence of prostate cancer has increased in Vietnam, but there have been few studies of the risk factors associated with this change. This retrospective case-control study investigated the relation of the intake of carotenoids and their food sources to prostate cancer risk. A sample of 652 participants (244 incident prostate cancer patients, aged 64-75 years, and 408 age frequency-matched controls) were recruited in Ho Chi Minh City during 2013-2015. The habitual diet was ascertained with a validated food-frequency questionnaire, and other factors including demographic and lifestyle characteristics were assessed via face-to-face interviews by trained nurses. Multivariate-adjusted odds ratios (OR) and 95% confidence intervals (CI) were estimated using unconditional logistic regression models. The risk of prostate cancer decreased with increasing intakes of lycopene, tomatoes, and carrots; the respective ORs (95% CIs) were 0.46 (0.27, 0.77), 0.39 (0.23, 0.66), and 0.35 (0.21, 0.58), when comparing the highest with the lowest tertile of intake (p for trend < 0.01). No statistically significant associations were found for the intake of α-carotene, β-carotene, β-cryptoxanthin, lutein, zeaxanthin, and major food sources of carotenoids. In conclusion, Vietnamese men with a higher intake of lycopene, tomatoes, and carrots may have a lower risk of prostate cancer. However, large prospective studies are needed in this population to confirm this finding.

Authors+Show Affiliations

National Institute of Hygiene and Epidemiology, Hanoi 100000, Vietnam. hdongyk97@gmail.com.School of Public Health, Curtin University, Perth, WA 6102, Australia. minh.pn@tnu.edu.vn. Thai Nguyen University of Medicine and Pharmacy, Thai Nguyen 250000, Vietnam. minh.pn@tnu.edu.vn.School of Public Health, Curtin University, Perth, WA 6102, Australia. andy.lee@curtin.edu.au.National Institute of Hygiene and Epidemiology, Hanoi 100000, Vietnam. trannhuduong@gmail.com.School of Public Health, Curtin University, Perth, WA 6102, Australia. c.binns@curtin.edu.au.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29324670

Citation

Van Hoang, Dong, et al. "Dietary Carotenoid Intakes and Prostate Cancer Risk: a Case-Control Study From Vietnam." Nutrients, vol. 10, no. 1, 2018.
Van Hoang D, Pham NM, Lee AH, et al. Dietary Carotenoid Intakes and Prostate Cancer Risk: A Case-Control Study from Vietnam. Nutrients. 2018;10(1).
Van Hoang, D., Pham, N. M., Lee, A. H., Tran, D. N., & Binns, C. W. (2018). Dietary Carotenoid Intakes and Prostate Cancer Risk: A Case-Control Study from Vietnam. Nutrients, 10(1), doi:10.3390/nu10010070.
Van Hoang D, et al. Dietary Carotenoid Intakes and Prostate Cancer Risk: a Case-Control Study From Vietnam. Nutrients. 2018 Jan 11;10(1) PubMed PMID: 29324670.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dietary Carotenoid Intakes and Prostate Cancer Risk: A Case-Control Study from Vietnam. AU - Van Hoang,Dong, AU - Pham,Ngoc Minh, AU - Lee,Andy H, AU - Tran,Duong Nhu, AU - Binns,Colin W, Y1 - 2018/01/11/ PY - 2017/11/28/received PY - 2018/01/09/revised PY - 2018/01/09/accepted PY - 2018/1/12/entrez PY - 2018/1/13/pubmed PY - 2018/8/7/medline KW - Vietnam KW - carotenoids KW - case-control study KW - epidemiology KW - prostate cancer JF - Nutrients JO - Nutrients VL - 10 IS - 1 N2 - The incidence of prostate cancer has increased in Vietnam, but there have been few studies of the risk factors associated with this change. This retrospective case-control study investigated the relation of the intake of carotenoids and their food sources to prostate cancer risk. A sample of 652 participants (244 incident prostate cancer patients, aged 64-75 years, and 408 age frequency-matched controls) were recruited in Ho Chi Minh City during 2013-2015. The habitual diet was ascertained with a validated food-frequency questionnaire, and other factors including demographic and lifestyle characteristics were assessed via face-to-face interviews by trained nurses. Multivariate-adjusted odds ratios (OR) and 95% confidence intervals (CI) were estimated using unconditional logistic regression models. The risk of prostate cancer decreased with increasing intakes of lycopene, tomatoes, and carrots; the respective ORs (95% CIs) were 0.46 (0.27, 0.77), 0.39 (0.23, 0.66), and 0.35 (0.21, 0.58), when comparing the highest with the lowest tertile of intake (p for trend < 0.01). No statistically significant associations were found for the intake of α-carotene, β-carotene, β-cryptoxanthin, lutein, zeaxanthin, and major food sources of carotenoids. In conclusion, Vietnamese men with a higher intake of lycopene, tomatoes, and carrots may have a lower risk of prostate cancer. However, large prospective studies are needed in this population to confirm this finding. SN - 2072-6643 UR - https://www.unboundmedicine.com/medline/citation/29324670/Dietary_Carotenoid_Intakes_and_Prostate_Cancer_Risk:_A_Case_Control_Study_from_Vietnam_ L2 - http://www.mdpi.com/resolver?pii=nu10010070 DB - PRIME DP - Unbound Medicine ER -