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Preparation and evaluation of antibacterial potential of Pithecellobium dulce root extract against Gram positive and Gram negative bacteria.
Microb Pathog 2018; 116:49-53MP

Abstract

In the present study hexane, benzene, ethyl acetate and ethanol extracts of Pithecellobium dulce root were prepared using soxhlet extractor. The extracts were evaluated for antibacterial activity against one Gram positive (Staphylococcus aureus) and three Gram negative (Acetobacter aceti, Acetobacter aceti, Klebsiella pneumoniae) strains. Disc diffusion method revealed promising antibacterial activity of the extracts prepared in polar solvents (ethyl acetate and ethanol) compared to non-polar solvents (hexane and benzene). Ethanolic root extract was found to be most active against Acetobacter aceti, Staphylococcus aureus, Klebsiella pneumonia and Enterobacter aerogenes bacterial strains. The zone of inhibition of ethanolic root extract against Acetobacter aceti, Staphylococcus aureus, Klebsiella pneumonia and Enterobacter aerogenes bacterial strains was 15.4, 11.0, 19.0 and 13.0 mm, respectively at 100 mg concentration. Ethyl acetate extract also exhibited good antibacterial activity against Entrobacter aerogenes, Klebsiella pneumonia and Acetobacter aceti. The zone of inhibition of ethyl acetate root extracts against Entrobacter aerogenes, Acetobacter aceti and Klebsiella pneumonia was 10.5, 18.0 and 10.0 mm, respectively. The benzene extract showed some activity against Acetobacter aceti with the zone of inhibition 10.0 mm. The antibacterial activity of Pithecellobium dulce root hexane extract was found to be negligible against all the four tested strains of bacteria. These findings suggest that ethanolic and ethyl acetate root extracts of Pithecellobium dulce has potential as effective anti-bacterial agent.

Authors+Show Affiliations

Department of Chemistry, Faculty of Science, SHUATS, Allahabad, Utter Pradesh 211007, India.Department of Chemistry, Faculty of Science, SHUATS, Allahabad, Utter Pradesh 211007, India.Department of Chemistry, Faculty of Science, SHUATS, Allahabad, Utter Pradesh 211007, India.Laboratory of Organic Synthesis, Department of Chemistry, Govt. Degree College for Women Baramulla, Jammu & Kashmir 193101, India. Electronic address: loneali33@gmail.com.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29331370

Citation

Bhat, Muneer Ahmad, et al. "Preparation and Evaluation of Antibacterial Potential of Pithecellobium Dulce Root Extract Against Gram Positive and Gram Negative Bacteria." Microbial Pathogenesis, vol. 116, 2018, pp. 49-53.
Bhat MA, Malik RA, Prakash P, et al. Preparation and evaluation of antibacterial potential of Pithecellobium dulce root extract against Gram positive and Gram negative bacteria. Microb Pathog. 2018;116:49-53.
Bhat, M. A., Malik, R. A., Prakash, P., & Lone, A. M. (2018). Preparation and evaluation of antibacterial potential of Pithecellobium dulce root extract against Gram positive and Gram negative bacteria. Microbial Pathogenesis, 116, pp. 49-53. doi:10.1016/j.micpath.2018.01.013.
Bhat MA, et al. Preparation and Evaluation of Antibacterial Potential of Pithecellobium Dulce Root Extract Against Gram Positive and Gram Negative Bacteria. Microb Pathog. 2018;116:49-53. PubMed PMID: 29331370.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Preparation and evaluation of antibacterial potential of Pithecellobium dulce root extract against Gram positive and Gram negative bacteria. AU - Bhat,Muneer Ahmad, AU - Malik,Rayees Ahmad, AU - Prakash,Poonam, AU - Lone,Ali Mohd, Y1 - 2018/01/10/ PY - 2017/12/10/received PY - 2018/01/08/revised PY - 2018/01/09/accepted PY - 2018/1/15/pubmed PY - 2018/8/31/medline PY - 2018/1/15/entrez KW - Chemotherapy KW - Dermatophytic KW - Herbal antibiotics KW - Pathogenic KW - Pithecellobium dulce SP - 49 EP - 53 JF - Microbial pathogenesis JO - Microb. Pathog. VL - 116 N2 - In the present study hexane, benzene, ethyl acetate and ethanol extracts of Pithecellobium dulce root were prepared using soxhlet extractor. The extracts were evaluated for antibacterial activity against one Gram positive (Staphylococcus aureus) and three Gram negative (Acetobacter aceti, Acetobacter aceti, Klebsiella pneumoniae) strains. Disc diffusion method revealed promising antibacterial activity of the extracts prepared in polar solvents (ethyl acetate and ethanol) compared to non-polar solvents (hexane and benzene). Ethanolic root extract was found to be most active against Acetobacter aceti, Staphylococcus aureus, Klebsiella pneumonia and Enterobacter aerogenes bacterial strains. The zone of inhibition of ethanolic root extract against Acetobacter aceti, Staphylococcus aureus, Klebsiella pneumonia and Enterobacter aerogenes bacterial strains was 15.4, 11.0, 19.0 and 13.0 mm, respectively at 100 mg concentration. Ethyl acetate extract also exhibited good antibacterial activity against Entrobacter aerogenes, Klebsiella pneumonia and Acetobacter aceti. The zone of inhibition of ethyl acetate root extracts against Entrobacter aerogenes, Acetobacter aceti and Klebsiella pneumonia was 10.5, 18.0 and 10.0 mm, respectively. The benzene extract showed some activity against Acetobacter aceti with the zone of inhibition 10.0 mm. The antibacterial activity of Pithecellobium dulce root hexane extract was found to be negligible against all the four tested strains of bacteria. These findings suggest that ethanolic and ethyl acetate root extracts of Pithecellobium dulce has potential as effective anti-bacterial agent. SN - 1096-1208 UR - https://www.unboundmedicine.com/medline/citation/29331370/Preparation_and_evaluation_of_antibacterial_potential_of_Pithecellobium_dulce_root_extract_against_Gram_positive_and_Gram_negative_bacteria_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0882-4010(17)31696-0 DB - PRIME DP - Unbound Medicine ER -