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Silver ion-enhanced particle-specific cytotoxicity of silver nanoparticles and effect on the production of extracellular secretions of Phanerochaete chrysosporium.
Chemosphere. 2018 Apr; 196:575-584.C

Abstract

This study investigated the influence of silver ions (Ag+) on the cytotoxicity of silver nanoparticles (AgNPs) in Phanerochaete chrysosporium and noted the degree of extracellular secretions in response to the toxicant's stress. Oxalate production was elicited with moderate concentrations of 2,4-dichlorophenol (2,4-DCP) and AgNPs reaching a plateau at 10 mg/L and 10 μM, respectively. Increased oxalate accumulation was accompanied by higher activities of manganese peroxidase (MnP) and lignin peroxidase (LiP). However, the secretion of oxalate, MnP and LiP was significantly inhibited owing to Ag+ incorporation into AgNP solution. Production of extracellular polymeric substances (EPS) significantly elevated with an increase in 2,4-DCP concentrations; however, after 24 h of exposure to 100 mg/L 2,4-DCP, an obvious decrease in EPS occurred, indicating that part of EPS could be consumed as carbon and energy sources to ameliorate biological tolerance to toxic stress. Furthermore, AgNP-induced "particle-specific" cytotoxicity was substantially enhanced with additional Ag+ as evidenced by its significant negative impact on cellular growth, plasma membrane integrity, and morphological preservation compared with AgNPs at equal Ag concentration.

Authors+Show Affiliations

College of Environmental Science and Engineering, Hunan University, Changsha, 410082, PR China; Key Laboratory of Environmental Biology and Pollution Control (Hunan University), Ministry of Education, Changsha, 410082, PR China.College of Environmental Science and Engineering, Hunan University, Changsha, 410082, PR China; Key Laboratory of Environmental Biology and Pollution Control (Hunan University), Ministry of Education, Changsha, 410082, PR China.College of Environmental Science and Engineering, Hunan University, Changsha, 410082, PR China; Key Laboratory of Environmental Biology and Pollution Control (Hunan University), Ministry of Education, Changsha, 410082, PR China.College of Environmental Science and Engineering, Hunan University, Changsha, 410082, PR China; Key Laboratory of Environmental Biology and Pollution Control (Hunan University), Ministry of Education, Changsha, 410082, PR China. Electronic address: zgming@hnu.edu.cn.College of Resources and Environment, Hunan Agricultural University, Changsha, 410128, PR China. Electronic address: A.Chen@hunau.edu.cn.School of Municipal and Environmental Engineering, Henan University of Urban Construction, Pingdingshan, 467036, PR China.College of Environmental Science and Engineering, Hunan University, Changsha, 410082, PR China; Key Laboratory of Environmental Biology and Pollution Control (Hunan University), Ministry of Education, Changsha, 410082, PR China.College of Environmental Science and Engineering, Hunan University, Changsha, 410082, PR China; Key Laboratory of Environmental Biology and Pollution Control (Hunan University), Ministry of Education, Changsha, 410082, PR China.College of Environmental Science and Engineering, Hunan University, Changsha, 410082, PR China; Key Laboratory of Environmental Biology and Pollution Control (Hunan University), Ministry of Education, Changsha, 410082, PR China.College of Environmental Science and Engineering, Hunan University, Changsha, 410082, PR China; Key Laboratory of Environmental Biology and Pollution Control (Hunan University), Ministry of Education, Changsha, 410082, PR China.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29331621

Citation

Huang, Zhenzhen, et al. "Silver Ion-enhanced Particle-specific Cytotoxicity of Silver Nanoparticles and Effect On the Production of Extracellular Secretions of Phanerochaete Chrysosporium." Chemosphere, vol. 196, 2018, pp. 575-584.
Huang Z, Xu P, Chen G, et al. Silver ion-enhanced particle-specific cytotoxicity of silver nanoparticles and effect on the production of extracellular secretions of Phanerochaete chrysosporium. Chemosphere. 2018;196:575-584.
Huang, Z., Xu, P., Chen, G., Zeng, G., Chen, A., Song, Z., He, K., Yuan, L., Li, H., & Hu, L. (2018). Silver ion-enhanced particle-specific cytotoxicity of silver nanoparticles and effect on the production of extracellular secretions of Phanerochaete chrysosporium. Chemosphere, 196, 575-584. https://doi.org/10.1016/j.chemosphere.2017.12.185
Huang Z, et al. Silver Ion-enhanced Particle-specific Cytotoxicity of Silver Nanoparticles and Effect On the Production of Extracellular Secretions of Phanerochaete Chrysosporium. Chemosphere. 2018;196:575-584. PubMed PMID: 29331621.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Silver ion-enhanced particle-specific cytotoxicity of silver nanoparticles and effect on the production of extracellular secretions of Phanerochaete chrysosporium. AU - Huang,Zhenzhen, AU - Xu,Piao, AU - Chen,Guiqiu, AU - Zeng,Guangming, AU - Chen,Anwei, AU - Song,Zhongxian, AU - He,Kai, AU - Yuan,Lei, AU - Li,Hui, AU - Hu,Liang, Y1 - 2017/12/30/ PY - 2017/09/01/received PY - 2017/12/19/revised PY - 2017/12/28/accepted PY - 2018/1/15/pubmed PY - 2018/3/13/medline PY - 2018/1/15/entrez KW - Enhanced “particle-specific” cytotoxicity KW - Extracellular secretions KW - Phanerochaete chrysosporium KW - Silver ions KW - Silver nanoparticles SP - 575 EP - 584 JF - Chemosphere JO - Chemosphere VL - 196 N2 - This study investigated the influence of silver ions (Ag+) on the cytotoxicity of silver nanoparticles (AgNPs) in Phanerochaete chrysosporium and noted the degree of extracellular secretions in response to the toxicant's stress. Oxalate production was elicited with moderate concentrations of 2,4-dichlorophenol (2,4-DCP) and AgNPs reaching a plateau at 10 mg/L and 10 μM, respectively. Increased oxalate accumulation was accompanied by higher activities of manganese peroxidase (MnP) and lignin peroxidase (LiP). However, the secretion of oxalate, MnP and LiP was significantly inhibited owing to Ag+ incorporation into AgNP solution. Production of extracellular polymeric substances (EPS) significantly elevated with an increase in 2,4-DCP concentrations; however, after 24 h of exposure to 100 mg/L 2,4-DCP, an obvious decrease in EPS occurred, indicating that part of EPS could be consumed as carbon and energy sources to ameliorate biological tolerance to toxic stress. Furthermore, AgNP-induced "particle-specific" cytotoxicity was substantially enhanced with additional Ag+ as evidenced by its significant negative impact on cellular growth, plasma membrane integrity, and morphological preservation compared with AgNPs at equal Ag concentration. SN - 1879-1298 UR - https://www.unboundmedicine.com/medline/citation/29331621/Silver_ion-enhanced_particle-specific_cytotoxicity_of_silver_nanoparticles_and_effect_on_the_production_of_extracellular_secretions_of_Phanerochaete_chrysosporium L2 - https://linkinghub.elsevier.com/retrieve/pii/S0045-6535(17)32163-X DB - PRIME DP - Unbound Medicine ER -