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Efficacy of electrical acupuncture on vascular cognitive impairment with no dementia: study protocol for a randomized controlled trial.
Trials. 2018 Jan 19; 19(1):52.T

Abstract

BACKGROUND

Vascular cognitive impairment with no dementia (VCIND), manifested mainly as mild impairment of concentration and executive function, is the early phase of vascular dementia (VD). Currently, there is no specific treatment for VCIND. We hypothesize that electrical acupuncture can improve the mental and motor functions of patients with VCIND. Thus, we designed this randomized controlled trial to test this hypothesis by comparing the therapeutic effect of electrical acupuncture versus sham acupuncture in patients with VCIND.

METHOD/DESIGN

In this single-center 3-year study, 120 eligible patients will be recruited and randomly assigned to receive electrical acupuncture treatment (n = 60) or sham acupuncture (n = 60) for 8 consecutive weeks (24 sessions in total), with the same acupoint prescription (DU20, EX-HN3, DU24, DU17, DU26, EX-HN1, HT7, PC6, GB20, SP6). The primary assessment is the Montreal Cognitive Assessment. The secondary assessments are the Modified Barthel Index and Event-Related Potential. All outcomes will be assessed at baseline, endpoint, and follow-up at 8 and 24 weeks after the end of treatment.

DISCUSSION

If the outcome confirms the effectiveness and safety of electrical acupuncture in treating VCIND, this treatment is expected to be promoted in clinical practice to treat such patients.

TRIAL REGISTRATION

Chinese Clinical Trial Registry identifier: ChiCTR-IIR-17011513 ; Registered on 27 May 2017.

Authors+Show Affiliations

Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200071, China.Shanghai Research Institute of Acupuncture and Meridian, Shanghai University of Traditional Chinese Medicine, Shanghai, 200030, China.Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200071, China.Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200071, China.Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200071, China.University of Maryland School of Medicine, Baltimore, MD, 21201, USA. School of Chinese Medicine, The University of Hong Kong, Hong Kong, China.Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200071, China. xu_teacher2006@126.com.

Pub Type(s)

Clinical Trial Protocol
Journal Article

Language

eng

PubMed ID

29351791

Citation

Li, Tian, et al. "Efficacy of Electrical Acupuncture On Vascular Cognitive Impairment With No Dementia: Study Protocol for a Randomized Controlled Trial." Trials, vol. 19, no. 1, 2018, p. 52.
Li T, Wu H, Soto-Aguliar F, et al. Efficacy of electrical acupuncture on vascular cognitive impairment with no dementia: study protocol for a randomized controlled trial. Trials. 2018;19(1):52.
Li, T., Wu, H., Soto-Aguliar, F., Huang, L., Li, W., Lao, L., & Xu, S. (2018). Efficacy of electrical acupuncture on vascular cognitive impairment with no dementia: study protocol for a randomized controlled trial. Trials, 19(1), 52. https://doi.org/10.1186/s13063-018-2458-1
Li T, et al. Efficacy of Electrical Acupuncture On Vascular Cognitive Impairment With No Dementia: Study Protocol for a Randomized Controlled Trial. Trials. 2018 Jan 19;19(1):52. PubMed PMID: 29351791.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Efficacy of electrical acupuncture on vascular cognitive impairment with no dementia: study protocol for a randomized controlled trial. AU - Li,Tian, AU - Wu,Huangan, AU - Soto-Aguliar,Franscisca, AU - Huang,Li, AU - Li,Wentao, AU - Lao,Lixing, AU - Xu,Shifen, Y1 - 2018/01/19/ PY - 2017/08/22/received PY - 2018/01/04/accepted PY - 2018/1/21/entrez PY - 2018/1/21/pubmed PY - 2019/3/30/medline KW - Electrical acupuncture KW - Vascular cognitive impairment with no dementia (VCIND) KW - Vascular dementia (VD) SP - 52 EP - 52 JF - Trials JO - Trials VL - 19 IS - 1 N2 - BACKGROUND: Vascular cognitive impairment with no dementia (VCIND), manifested mainly as mild impairment of concentration and executive function, is the early phase of vascular dementia (VD). Currently, there is no specific treatment for VCIND. We hypothesize that electrical acupuncture can improve the mental and motor functions of patients with VCIND. Thus, we designed this randomized controlled trial to test this hypothesis by comparing the therapeutic effect of electrical acupuncture versus sham acupuncture in patients with VCIND. METHOD/DESIGN: In this single-center 3-year study, 120 eligible patients will be recruited and randomly assigned to receive electrical acupuncture treatment (n = 60) or sham acupuncture (n = 60) for 8 consecutive weeks (24 sessions in total), with the same acupoint prescription (DU20, EX-HN3, DU24, DU17, DU26, EX-HN1, HT7, PC6, GB20, SP6). The primary assessment is the Montreal Cognitive Assessment. The secondary assessments are the Modified Barthel Index and Event-Related Potential. All outcomes will be assessed at baseline, endpoint, and follow-up at 8 and 24 weeks after the end of treatment. DISCUSSION: If the outcome confirms the effectiveness and safety of electrical acupuncture in treating VCIND, this treatment is expected to be promoted in clinical practice to treat such patients. TRIAL REGISTRATION: Chinese Clinical Trial Registry identifier: ChiCTR-IIR-17011513 ; Registered on 27 May 2017. SN - 1745-6215 UR - https://www.unboundmedicine.com/medline/citation/29351791/Efficacy_of_electrical_acupuncture_on_vascular_cognitive_impairment_with_no_dementia:_study_protocol_for_a_randomized_controlled_trial_ L2 - https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-018-2458-1 DB - PRIME DP - Unbound Medicine ER -