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Image quality in coronary computed tomography angiography: influence of adaptive statistical iterative reconstruction at various radiation dose levels.
Acta Radiol. 2018 Oct; 59(10):1194-1202.AR

Abstract

Background Computed tomography (CT) technology is rapidly evolving and software solution developed to optimize image quality and/or lower radiation dose. Purpose To investigate the influence of adaptive statistical iterative reconstruction (ASIR) at different radiation doses in coronary CT angiography (CCTA) in detailed image quality. Material and Methods A total of 160 CCTA were reconstructed as follows: 55 scans with filtered back projection (FBP) (650 mA), 51 scans (455 mA) with 30% ASIR (ASIR30), and 54 scans (295 mA) with 60% ASIR (ASIR60). For each reconstruction, subjective image quality was assessed by five independent certified cardiologists using a visual grading analysis (VGA) with five predefined image quality criteria consisting of a 5-point scale. Objective measures were contrast, noise, and contrast-to-noise ratio (CNR). Results The CTDIvol resulted in 10.3 mGy, 7.4 mGy, and 4.6 mGy for FBP, ASIR30, and ASIR60, respectively. Homogeneity of the left ventricular lumen was the sole aspect in which reconstruction algorithms differed with a decreasing effect for ASIR60 compared to FBP (estimated odds ratio [OR] = 0.49 [95% confidence interval (CI) = 0.32-0.76; P = 0.001]). Decreased sharpness and spatial- and low-contrast resolutions were observed when using ASIR instead of FBP, but differences were not statistically significant. Concerning objective measurements, noise increased significantly for ASIR30 (OR = 1.08; 95% CI = 1.02-1.14; P = 0.006) and ASIR60 (OR = 1.06; 95% CI = 1.01-1.12; P = 0.034) compared to FBP. Conclusion ASIR significantly decreased the subjectively assessed homogeneity of the left ventricular lumen and increased the objectively measured noise compared to FBP. Considering these results, ASIR at a reduced radiation dose should be implemented with caution.

Authors+Show Affiliations

1 Department of Medical Research, Odense University Hospital Svendborg, Svendborg, Denmark. 2 Conrad Research Center, University College Lillebelt, Odense, Denmark.3 Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark. 4 Centre of Health Economics Research, University of Southern Denmark, Odense, Denmark.5 Department of Clinical Engineering, Central Denmark Region, Århus, Denmark.1 Department of Medical Research, Odense University Hospital Svendborg, Svendborg, Denmark.1 Department of Medical Research, Odense University Hospital Svendborg, Svendborg, Denmark.6 Norwegian University of Science and Technology, Gjøvik, Norway.1 Department of Medical Research, Odense University Hospital Svendborg, Svendborg, Denmark.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29359950

Citation

Precht, Helle, et al. "Image Quality in Coronary Computed Tomography Angiography: Influence of Adaptive Statistical Iterative Reconstruction at Various Radiation Dose Levels." Acta Radiologica (Stockholm, Sweden : 1987), vol. 59, no. 10, 2018, pp. 1194-1202.
Precht H, Gerke O, Thygesen J, et al. Image quality in coronary computed tomography angiography: influence of adaptive statistical iterative reconstruction at various radiation dose levels. Acta Radiol. 2018;59(10):1194-1202.
Precht, H., Gerke, O., Thygesen, J., Egstrup, K., Auscher, S., Waaler, D., & Lambrechtsen, J. (2018). Image quality in coronary computed tomography angiography: influence of adaptive statistical iterative reconstruction at various radiation dose levels. Acta Radiologica (Stockholm, Sweden : 1987), 59(10), 1194-1202. https://doi.org/10.1177/0284185117753657
Precht H, et al. Image Quality in Coronary Computed Tomography Angiography: Influence of Adaptive Statistical Iterative Reconstruction at Various Radiation Dose Levels. Acta Radiol. 2018;59(10):1194-1202. PubMed PMID: 29359950.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Image quality in coronary computed tomography angiography: influence of adaptive statistical iterative reconstruction at various radiation dose levels. AU - Precht,Helle, AU - Gerke,Oke, AU - Thygesen,Jesper, AU - Egstrup,Kenneth, AU - Auscher,Søren, AU - Waaler,Dag, AU - Lambrechtsen,Jess, Y1 - 2018/01/23/ PY - 2018/1/24/pubmed PY - 2018/9/11/medline PY - 2018/1/24/entrez KW - CT angiography KW - Cardiac KW - image quality KW - iterative reconstruction KW - radiation safety KW - technical aspects SP - 1194 EP - 1202 JF - Acta radiologica (Stockholm, Sweden : 1987) JO - Acta Radiol VL - 59 IS - 10 N2 - Background Computed tomography (CT) technology is rapidly evolving and software solution developed to optimize image quality and/or lower radiation dose. Purpose To investigate the influence of adaptive statistical iterative reconstruction (ASIR) at different radiation doses in coronary CT angiography (CCTA) in detailed image quality. Material and Methods A total of 160 CCTA were reconstructed as follows: 55 scans with filtered back projection (FBP) (650 mA), 51 scans (455 mA) with 30% ASIR (ASIR30), and 54 scans (295 mA) with 60% ASIR (ASIR60). For each reconstruction, subjective image quality was assessed by five independent certified cardiologists using a visual grading analysis (VGA) with five predefined image quality criteria consisting of a 5-point scale. Objective measures were contrast, noise, and contrast-to-noise ratio (CNR). Results The CTDIvol resulted in 10.3 mGy, 7.4 mGy, and 4.6 mGy for FBP, ASIR30, and ASIR60, respectively. Homogeneity of the left ventricular lumen was the sole aspect in which reconstruction algorithms differed with a decreasing effect for ASIR60 compared to FBP (estimated odds ratio [OR] = 0.49 [95% confidence interval (CI) = 0.32-0.76; P = 0.001]). Decreased sharpness and spatial- and low-contrast resolutions were observed when using ASIR instead of FBP, but differences were not statistically significant. Concerning objective measurements, noise increased significantly for ASIR30 (OR = 1.08; 95% CI = 1.02-1.14; P = 0.006) and ASIR60 (OR = 1.06; 95% CI = 1.01-1.12; P = 0.034) compared to FBP. Conclusion ASIR significantly decreased the subjectively assessed homogeneity of the left ventricular lumen and increased the objectively measured noise compared to FBP. Considering these results, ASIR at a reduced radiation dose should be implemented with caution. SN - 1600-0455 UR - https://www.unboundmedicine.com/medline/citation/29359950/Image_quality_in_coronary_computed_tomography_angiography:_influence_of_adaptive_statistical_iterative_reconstruction_at_various_radiation_dose_levels_ L2 - https://journals.sagepub.com/doi/10.1177/0284185117753657?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -