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"Maxillary lateral incisor partial anodontia sequence": a clinical entity with epigenetic origin.
Dental Press J Orthod 2017 Nov-Dec; 22(6):28-34DP

Abstract

The relationship between maxillary lateral incisor anodontia and the palatal displacement of unerupted maxillary canines cannot be considered as a multiple tooth abnormality with defined genetic etiology in order to be regarded as a "syndrome". Neither were the involved genes identified and located in the human genome, nor was it presumed on which chromosome the responsible gene would be located. The palatal maxillary canine displacement in cases of partial anodontia of the maxillary lateral incisor is potentially associated with environmental changes caused by its absence in its place of formation and eruption, which would characterize an epigenetic etiology. The lack of the maxillary lateral incisor in the canine region means removing one of the reference guides for the eruptive trajectory of the maxillary canine, which would therefore, not erupt and /or impact on the palate. Consequently, and in sequence, it would lead to malocclusion, maxillary atresia, transposition, prolonged retention of the deciduous canine and resorption in the neighboring teeth. Thus, we can say that we are dealing with a set of anomalies and multiple sequential changes known as sequential development anomalies or, simply, sequence. Once the epigenetics and sequential condition is accepted for this clinical picture, it could be called "Maxillary Lateral Incisor Partial Anodontia Sequence."

Authors+Show Affiliations

Universidade de São Paulo, Faculdade de Odontologia de Bauru (Bauru/SP, Brazil). Universidade de São Paulo, Faculdade de Odontologia de Ribeirão Preto, Programa de Pós-graduação em Odontopediatria (Ribeirão Preto/SP, Brazil).Faculdade de Medicina e Odontologia São Leopoldo Mandic, Disciplina de Ortodontia (Campinas/SP, Brazil).Faculdades Integradas de Adamantina, Disciplina de Patologia Bucal (Adamantina/SP, Brazil).

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29364376

Citation

Consolaro, Alberto, et al. ""Maxillary Lateral Incisor Partial Anodontia Sequence": a Clinical Entity With Epigenetic Origin." Dental Press Journal of Orthodontics, vol. 22, no. 6, 2017, pp. 28-34.
Consolaro A, Cardoso MA, Consolaro RB. "Maxillary lateral incisor partial anodontia sequence": a clinical entity with epigenetic origin. Dental Press J Orthod. 2017;22(6):28-34.
Consolaro, A., Cardoso, M. A., & Consolaro, R. B. (2017). "Maxillary lateral incisor partial anodontia sequence": a clinical entity with epigenetic origin. Dental Press Journal of Orthodontics, 22(6), pp. 28-34. doi:10.1590/2177-6709.22.6.028-034.oin.
Consolaro A, Cardoso MA, Consolaro RB. "Maxillary Lateral Incisor Partial Anodontia Sequence": a Clinical Entity With Epigenetic Origin. Dental Press J Orthod. 2017;22(6):28-34. PubMed PMID: 29364376.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - "Maxillary lateral incisor partial anodontia sequence": a clinical entity with epigenetic origin. AU - Consolaro,Alberto, AU - Cardoso,Maurício Almeida, AU - Consolaro,Renata Bianco, PY - 2017/09/20/received PY - 2017/10/09/accepted PY - 2018/1/25/entrez PY - 2018/1/25/pubmed PY - 2018/8/30/medline SP - 28 EP - 34 JF - Dental press journal of orthodontics JO - Dental Press J Orthod VL - 22 IS - 6 N2 - The relationship between maxillary lateral incisor anodontia and the palatal displacement of unerupted maxillary canines cannot be considered as a multiple tooth abnormality with defined genetic etiology in order to be regarded as a "syndrome". Neither were the involved genes identified and located in the human genome, nor was it presumed on which chromosome the responsible gene would be located. The palatal maxillary canine displacement in cases of partial anodontia of the maxillary lateral incisor is potentially associated with environmental changes caused by its absence in its place of formation and eruption, which would characterize an epigenetic etiology. The lack of the maxillary lateral incisor in the canine region means removing one of the reference guides for the eruptive trajectory of the maxillary canine, which would therefore, not erupt and /or impact on the palate. Consequently, and in sequence, it would lead to malocclusion, maxillary atresia, transposition, prolonged retention of the deciduous canine and resorption in the neighboring teeth. Thus, we can say that we are dealing with a set of anomalies and multiple sequential changes known as sequential development anomalies or, simply, sequence. Once the epigenetics and sequential condition is accepted for this clinical picture, it could be called "Maxillary Lateral Incisor Partial Anodontia Sequence." SN - 2177-6709 UR - https://www.unboundmedicine.com/medline/citation/29364376/"Maxillary_lateral_incisor_partial_anodontia_sequence":_a_clinical_entity_with_epigenetic_origin_ L2 - http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2176-94512017000600028&lng=en&nrm=iso&tlng=en DB - PRIME DP - Unbound Medicine ER -