Tags

Type your tag names separated by a space and hit enter

Association of Long-Term Adherence to the MIND Diet with Cognitive Function and Cognitive Decline in American Women.
J Nutr Health Aging. 2018; 22(2):222-229.JN

Abstract

OBJECTIVES

There is increasing attention for dietary patterns as a potential strategy to prevent cognitive decline. We examined the association between adherence to a recently developed Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet with cognitive function and cognitive decline, taking into account the interaction between the apolipoprotein E ε4 genotype and the MIND diet.

DESIGN

Population-based prospective cohort study.

PARTICIPANTS

A total of 16,058 older women aged 70 and over from the Nurses' Health Study.

MEASUREMENTS

Dietary intake was assessed five times between 1984 and 1998 with a 116-item Food Frequency Questionnaire. The MIND score includes ten brain-healthy foods and five unhealthy foods. Cognition was assessed four times by telephone from 1995 to 2001 (baseline) with the Telephone Interview for Cognitive Status (TICS) and by calculating composite scores of verbal memory and global cognition. Linear regression modelling and linear mixed modelling were used to examine the associations of adherence to the MIND diet with average cognitive function and cognitive change over six years, respectively.

RESULTS

Greater long-term adherence to the MIND diet was associated with a better verbal memory score (multivariable-adjusted mean differences between extreme MIND quintiles=0.04 (95%CI 0.01-0.07), p-trend=0.006), but not with cognitive decline over 6 years in global cognition, verbal memory or TICS.

CONCLUSION

Long-term adherence to the MIND diet was moderately associated with better verbal memory in later life. Future studies should address this association within populations at greater risk of cognitive decline.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Berendsen AM
Agnes Berendsen, Wageningen University, Division of Human Nutrition, PO Box 17, 6700 AA, Wageningen, the Netherlands, Phone: +31 317 485898, fax: +31 317 482782, e-mail: Agnes.Berendsen@wur.nl.
Kang JH
No affiliation info available
Feskens EJM
No affiliation info available
de Groot CPGM
No affiliation info available
Grodstein F
No affiliation info available
van de Rest O
No affiliation info available

MeSH

AdultCognitionCognitive DysfunctionCohort StudiesDiet, MediterraneanFemaleHumansMiddle AgedProspective StudiesSurveys and QuestionnairesUnited States

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

29380849

Citation

Berendsen, A M., et al. "Association of Long-Term Adherence to the MIND Diet With Cognitive Function and Cognitive Decline in American Women." The Journal of Nutrition, Health & Aging, vol. 22, no. 2, 2018, pp. 222-229.
Berendsen AM, Kang JH, Feskens EJM, et al. Association of Long-Term Adherence to the MIND Diet with Cognitive Function and Cognitive Decline in American Women. J Nutr Health Aging. 2018;22(2):222-229.
Berendsen, A. M., Kang, J. H., Feskens, E. J. M., de Groot, C. P. G. M., Grodstein, F., & van de Rest, O. (2018). Association of Long-Term Adherence to the MIND Diet with Cognitive Function and Cognitive Decline in American Women. The Journal of Nutrition, Health & Aging, 22(2), 222-229. https://doi.org/10.1007/s12603-017-0909-0
Berendsen AM, et al. Association of Long-Term Adherence to the MIND Diet With Cognitive Function and Cognitive Decline in American Women. J Nutr Health Aging. 2018;22(2):222-229. PubMed PMID: 29380849.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Association of Long-Term Adherence to the MIND Diet with Cognitive Function and Cognitive Decline in American Women. AU - Berendsen,A M, AU - Kang,J H, AU - Feskens,E J M, AU - de Groot,C P G M, AU - Grodstein,F, AU - van de Rest,O, PY - 2018/1/31/entrez PY - 2018/1/31/pubmed PY - 2019/9/17/medline KW - Cognition KW - DASH KW - MIND KW - Mediterranean KW - dietary pattern SP - 222 EP - 229 JF - The journal of nutrition, health & aging JO - J Nutr Health Aging VL - 22 IS - 2 N2 - OBJECTIVES: There is increasing attention for dietary patterns as a potential strategy to prevent cognitive decline. We examined the association between adherence to a recently developed Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet with cognitive function and cognitive decline, taking into account the interaction between the apolipoprotein E ε4 genotype and the MIND diet. DESIGN: Population-based prospective cohort study. PARTICIPANTS: A total of 16,058 older women aged 70 and over from the Nurses' Health Study. MEASUREMENTS: Dietary intake was assessed five times between 1984 and 1998 with a 116-item Food Frequency Questionnaire. The MIND score includes ten brain-healthy foods and five unhealthy foods. Cognition was assessed four times by telephone from 1995 to 2001 (baseline) with the Telephone Interview for Cognitive Status (TICS) and by calculating composite scores of verbal memory and global cognition. Linear regression modelling and linear mixed modelling were used to examine the associations of adherence to the MIND diet with average cognitive function and cognitive change over six years, respectively. RESULTS: Greater long-term adherence to the MIND diet was associated with a better verbal memory score (multivariable-adjusted mean differences between extreme MIND quintiles=0.04 (95%CI 0.01-0.07), p-trend=0.006), but not with cognitive decline over 6 years in global cognition, verbal memory or TICS. CONCLUSION: Long-term adherence to the MIND diet was moderately associated with better verbal memory in later life. Future studies should address this association within populations at greater risk of cognitive decline. SN - 1760-4788 UR - https://www.unboundmedicine.com/medline/citation/29380849/Association_of_Long_Term_Adherence_to_the_MIND_Diet_with_Cognitive_Function_and_Cognitive_Decline_in_American_Women_ DB - PRIME DP - Unbound Medicine ER -