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Adult hippocampal ganglioneuroblastoma: Case report and literature review.

Abstract

RATIONALE

Intracranial ganglioneuroblastoma represents a rare subtype of primitive neuroectodermal tumor. Here, we report a hippocampal ganglioneuroblastoma and a literature review of cerebral anglioneuroblastoma is carried out.

PATIENT CONCERNS

We report a 16-year-old male patient presenting with absence seizure and high-infiltration hippocampal ganglioneuroblastoma.

INTERVENTIONS

Magnetic resonance imaging (MRI) indicates a space-occupying lesion with a well-defined margin in the right temporal lobe and hippocampus. However, hyper-signal on flair and diffusion-weighted imaging (DWI) with a low apparent diffusion coefficient (ADC) value is detected, which prompts high tumoral invasiveness.

INTERVENTIONS

A total resection of tumor and subsequent chemotherapy combing with radiotherapy is performed.

OUTCOMES

For a follow-up period of 60 months, no evidence of recurrence and further seizures are detected.

LESSONS

High-infiltration hippocampal ganglioneuroblastoma is a rare event. MRI examination often showed features of low-grade gliomas, while hyper-signal lesion on DWI with a low ADC value can be detected. Complete resection combined with fractionated radiotherapy and chemotherapy was the optimal treatment for cerebral ganglioneuroblastoma.

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  • Authors+Show Affiliations

    ,

    Department of Neurosurgery.

    ,

    Department of Neurosurgery.

    ,

    Department of Critical Medicine.

    ,

    Department of Neurosurgery.

    ,

    Department of Pathology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, China.

    ,

    Department of Neurosurgery.

    Department of Neurosurgery.

    Source

    Medicine 96:51 2017 Dec pg e8894

    MeSH

    Adolescent
    Brain Neoplasms
    Combined Modality Therapy
    Diagnosis, Differential
    Ganglioneuroblastoma
    Hippocampus
    Humans
    Magnetic Resonance Imaging
    Male
    Seizures

    Pub Type(s)

    Case Reports
    Journal Article

    Language

    eng

    PubMed ID

    29390424

    Citation

    Yao, Pei-Sen, et al. "Adult Hippocampal Ganglioneuroblastoma: Case Report and Literature Review." Medicine, vol. 96, no. 51, 2017, pp. e8894.
    Yao PS, Chen GR, Shang-Guan HC, et al. Adult hippocampal ganglioneuroblastoma: Case report and literature review. Medicine (Baltimore). 2017;96(51):e8894.
    Yao, P. S., Chen, G. R., Shang-Guan, H. C., Lin, Q. S., Wang, X. F., Zheng, S. F., & Kang, D. Z. (2017). Adult hippocampal ganglioneuroblastoma: Case report and literature review. Medicine, 96(51), pp. e8894. doi:10.1097/MD.0000000000008894.
    Yao PS, et al. Adult Hippocampal Ganglioneuroblastoma: Case Report and Literature Review. Medicine (Baltimore). 2017;96(51):e8894. PubMed PMID: 29390424.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Adult hippocampal ganglioneuroblastoma: Case report and literature review. AU - Yao,Pei-Sen, AU - Chen,Guo-Rong, AU - Shang-Guan,Huang-Cheng, AU - Lin,Qing-Song, AU - Wang,Xing-Fu, AU - Zheng,Shu-Fa, AU - Kang,De-Zhi, PY - 2018/2/3/entrez PY - 2018/2/3/pubmed PY - 2018/2/14/medline SP - e8894 EP - e8894 JF - Medicine JO - Medicine (Baltimore) VL - 96 IS - 51 N2 - RATIONALE: Intracranial ganglioneuroblastoma represents a rare subtype of primitive neuroectodermal tumor. Here, we report a hippocampal ganglioneuroblastoma and a literature review of cerebral anglioneuroblastoma is carried out. PATIENT CONCERNS: We report a 16-year-old male patient presenting with absence seizure and high-infiltration hippocampal ganglioneuroblastoma. INTERVENTIONS: Magnetic resonance imaging (MRI) indicates a space-occupying lesion with a well-defined margin in the right temporal lobe and hippocampus. However, hyper-signal on flair and diffusion-weighted imaging (DWI) with a low apparent diffusion coefficient (ADC) value is detected, which prompts high tumoral invasiveness. INTERVENTIONS: A total resection of tumor and subsequent chemotherapy combing with radiotherapy is performed. OUTCOMES: For a follow-up period of 60 months, no evidence of recurrence and further seizures are detected. LESSONS: High-infiltration hippocampal ganglioneuroblastoma is a rare event. MRI examination often showed features of low-grade gliomas, while hyper-signal lesion on DWI with a low ADC value can be detected. Complete resection combined with fractionated radiotherapy and chemotherapy was the optimal treatment for cerebral ganglioneuroblastoma. SN - 1536-5964 UR - https://www.unboundmedicine.com/medline/citation/29390424/Adult_hippocampal_ganglioneuroblastoma:_Case_report_and_literature_review_ L2 - http://Insights.ovid.com/pubmed?pmid=29390424 DB - PRIME DP - Unbound Medicine ER -