Abstract
BACKGROUND
This study was performed to demonstrate the usefulness of horizontal and vertical sections of scalp biopsies in diagnosing various forms of primary alopecias and to highlight the importance of error-free grossing.
MATERIALS AND METHODS
A retrospective analytical review of 228 scalp biopsies was done, noting down the diagnostic histopathological features evident in horizontal and vertical sections of each cases. The idealness of the sections, especially horizontal section, was also analyzed.
RESULTS
Out of the 228 cases, 44 scalp biopsies were classified histologically as cicatricial alopecias and the remaining 162 as noncicatricial alopecia. 22 cases were inconclusive owing to erroneous grossing. We found horizontal sections to be more useful in cases of noncicatricial alopecias, whereas vertical sections proved superior in cicatricial alopecias.
CONCLUSION
Combining both horizontally and vertically sectioned scalp biopsies maximizes the diagnostic yield. When a single biopsy is submitted, the choice between horizontal and vertical section should depend on clinical diagnosis/suspicion.
TY - JOUR
T1 - Utility of horizontal and vertical sections of scalp biopsies in various forms of primary alopecias.
AU - Palo,Seetu,
AU - Biligi,Dayananda S,
PY - 2018/2/7/entrez
PY - 2018/2/7/pubmed
PY - 2018/2/7/medline
KW - Cicatricial alopecia
KW - horizontal section
KW - noncicatricial alopecia
KW - vertical section
SP - 95
EP - 100
JF - Journal of laboratory physicians
JO - J Lab Physicians
VL - 10
IS - 1
N2 - BACKGROUND: This study was performed to demonstrate the usefulness of horizontal and vertical sections of scalp biopsies in diagnosing various forms of primary alopecias and to highlight the importance of error-free grossing. MATERIALS AND METHODS: A retrospective analytical review of 228 scalp biopsies was done, noting down the diagnostic histopathological features evident in horizontal and vertical sections of each cases. The idealness of the sections, especially horizontal section, was also analyzed. RESULTS: Out of the 228 cases, 44 scalp biopsies were classified histologically as cicatricial alopecias and the remaining 162 as noncicatricial alopecia. 22 cases were inconclusive owing to erroneous grossing. We found horizontal sections to be more useful in cases of noncicatricial alopecias, whereas vertical sections proved superior in cicatricial alopecias. CONCLUSION: Combining both horizontally and vertically sectioned scalp biopsies maximizes the diagnostic yield. When a single biopsy is submitted, the choice between horizontal and vertical section should depend on clinical diagnosis/suspicion.
SN - 0974-2727
UR - https://www.unboundmedicine.com/medline/citation/29403214/Utility_of_horizontal_and_vertical_sections_of_scalp_biopsies_in_various_forms_of_primary_alopecias_
DB - PRIME
DP - Unbound Medicine
ER -
