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Long-term effects of vaginal erbium laser in the treatment of genitourinary syndrome of menopause.
Climacteric. 2018 04; 21(2):148-152.C

Abstract

OBJECTIVES

To evaluate the long-term efficacy of a second generation of vaginal laser treatment, the vaginal erbium laser, as a non-ablative photothermal therapy for the management of genitourinary syndrome of menopause.

METHODS

The study was performed using an erbium laser crystal yttrium-aluminum-garnet (XS Fotona Smooth™, Fotona, Ljubljana, Slovenia) with a wavelength of 2940 nm. Postmenopausal women (n = 205) were treated with three laser applications at 30-day intervals. Symptoms were assessed before and after treatment throughout 24 months, using the subjective visual analog scale (VAS) and the objective vaginal health index score (VHIS). In addition, postmenopausal women suffering from stress urinary incontinence were evaluated with the International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI SF).

RESULTS

Vaginal erbium laser treatment induced a significant (p < 0.01) decrease in VAS for both vaginal dryness and dyspareunia, as well an increase in VHIS (p < 0.01) up to the 12th month after the last laser treatment. The values returned to levels similar to the baseline after 18 and 24 months. In addition, vaginal erbium laser treatment improved mild-moderate stress urinary incontinence in 114 postmenopausal women. Less than 3% of patients discontinued treatment due to adverse events.

CONCLUSIONS

These results suggest that vaginal erbium laser may be effective and safe for the treatment of genitourinary syndrome of menopause.

Authors+Show Affiliations

a Department of Obstetrics and Gynecology , University Hospital of Pisa , Pisa , Italy.b Department of Obstetrics and Gynecology , Clinica Alemana, University of Development , Santiago , Chile.a Department of Obstetrics and Gynecology , University Hospital of Pisa , Pisa , Italy.c Department of Obstetrics and Gynecology , Catholic University of the Sacred Heart , Rome , Italy.a Department of Obstetrics and Gynecology , University Hospital of Pisa , Pisa , Italy.c Department of Obstetrics and Gynecology , Catholic University of the Sacred Heart , Rome , Italy.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29436235

Citation

Gambacciani, M, et al. "Long-term Effects of Vaginal Erbium Laser in the Treatment of Genitourinary Syndrome of Menopause." Climacteric : the Journal of the International Menopause Society, vol. 21, no. 2, 2018, pp. 148-152.
Gambacciani M, Levancini M, Russo E, et al. Long-term effects of vaginal erbium laser in the treatment of genitourinary syndrome of menopause. Climacteric. 2018;21(2):148-152.
Gambacciani, M., Levancini, M., Russo, E., Vacca, L., Simoncini, T., & Cervigni, M. (2018). Long-term effects of vaginal erbium laser in the treatment of genitourinary syndrome of menopause. Climacteric : the Journal of the International Menopause Society, 21(2), 148-152. https://doi.org/10.1080/13697137.2018.1436538
Gambacciani M, et al. Long-term Effects of Vaginal Erbium Laser in the Treatment of Genitourinary Syndrome of Menopause. Climacteric. 2018;21(2):148-152. PubMed PMID: 29436235.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Long-term effects of vaginal erbium laser in the treatment of genitourinary syndrome of menopause. AU - Gambacciani,M, AU - Levancini,M, AU - Russo,E, AU - Vacca,L, AU - Simoncini,T, AU - Cervigni,M, Y1 - 2018/02/13/ PY - 2018/2/14/pubmed PY - 2019/5/22/medline PY - 2018/2/14/entrez KW - Erbium laser KW - dyspareunia KW - genitourinary syndrome of menopause KW - menopause KW - stress urinary incontinence KW - vaginal atrophy SP - 148 EP - 152 JF - Climacteric : the journal of the International Menopause Society JO - Climacteric VL - 21 IS - 2 N2 - OBJECTIVES: To evaluate the long-term efficacy of a second generation of vaginal laser treatment, the vaginal erbium laser, as a non-ablative photothermal therapy for the management of genitourinary syndrome of menopause. METHODS: The study was performed using an erbium laser crystal yttrium-aluminum-garnet (XS Fotona Smooth™, Fotona, Ljubljana, Slovenia) with a wavelength of 2940 nm. Postmenopausal women (n = 205) were treated with three laser applications at 30-day intervals. Symptoms were assessed before and after treatment throughout 24 months, using the subjective visual analog scale (VAS) and the objective vaginal health index score (VHIS). In addition, postmenopausal women suffering from stress urinary incontinence were evaluated with the International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI SF). RESULTS: Vaginal erbium laser treatment induced a significant (p < 0.01) decrease in VAS for both vaginal dryness and dyspareunia, as well an increase in VHIS (p < 0.01) up to the 12th month after the last laser treatment. The values returned to levels similar to the baseline after 18 and 24 months. In addition, vaginal erbium laser treatment improved mild-moderate stress urinary incontinence in 114 postmenopausal women. Less than 3% of patients discontinued treatment due to adverse events. CONCLUSIONS: These results suggest that vaginal erbium laser may be effective and safe for the treatment of genitourinary syndrome of menopause. SN - 1473-0804 UR - https://www.unboundmedicine.com/medline/citation/29436235/Long_term_effects_of_vaginal_erbium_laser_in_the_treatment_of_genitourinary_syndrome_of_menopause_ DB - PRIME DP - Unbound Medicine ER -