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Protective effects of an extract of the freshwater microalga Scenedesmus rubescens on UV-irradiated skin cells.
Int J Cosmet Sci. 2018 Apr; 40(2):187-192.IJ

Abstract

BACKGROUND

Skin ageing results from intrinsic but also extrinsic factors of which UV irradiation is a main cause. It is hence of interest to have means to protect skin from UV irradiation-induced damage. We selected an extract of the freshwater microalga Scenedesmus rubescens and assessed its potential to protect skin from photoageing caused by UV irradiation.

METHODS

Skin cells in vitro and ex vivo were analysed for markers of UV irradiation-induced photodamage such as decreased viability, decreased collagen content, hyperpigmentation and sunburn cells.

RESULTS

We found that a dry extract of the microalga Scenedesmus rubescens was able to suppress cellular signs of ageing induced by UV irradiation. It enhanced dermal fibroblast viability, rescued dermal collagen content, inhibited the formation of sunburn cells and inhibited tyrosinase activity.

CONCLUSION

An extract of Scenedesmus rubescens showed broad activity against markers of UV irradiation-induced cutaneous ageing. It may therefore be used as a preventive or regenerative agent for anti-ageing strategies.

Authors+Show Affiliations

DSM Nutritional Products, Personal Care & Aroma, Wurmisweg 576, CH-4303, Kaiseraugst, Switzerland.IGV Institut für Getreideverarbeitung GmbH, Arthur Scheunert Allee 40-41, D-14558, Nuthetal, Germany.IGV Institut für Getreideverarbeitung GmbH, Arthur Scheunert Allee 40-41, D-14558, Nuthetal, Germany.Cutech srl, Via San Marco 9/M, I-35129, Padua, Italy.DSM Nutritional Products, Personal Care & Aroma, Wurmisweg 576, CH-4303, Kaiseraugst, Switzerland.DSM Nutritional Products, Personal Care & Aroma, Wurmisweg 576, CH-4303, Kaiseraugst, Switzerland.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29438574

Citation

Campiche, R, et al. "Protective Effects of an Extract of the Freshwater Microalga Scenedesmus Rubescens On UV-irradiated Skin Cells." International Journal of Cosmetic Science, vol. 40, no. 2, 2018, pp. 187-192.
Campiche R, Sandau P, Kurth E, et al. Protective effects of an extract of the freshwater microalga Scenedesmus rubescens on UV-irradiated skin cells. Int J Cosmet Sci. 2018;40(2):187-192.
Campiche, R., Sandau, P., Kurth, E., Massironi, M., Imfeld, D., & Schuetz, R. (2018). Protective effects of an extract of the freshwater microalga Scenedesmus rubescens on UV-irradiated skin cells. International Journal of Cosmetic Science, 40(2), 187-192. https://doi.org/10.1111/ics.12450
Campiche R, et al. Protective Effects of an Extract of the Freshwater Microalga Scenedesmus Rubescens On UV-irradiated Skin Cells. Int J Cosmet Sci. 2018;40(2):187-192. PubMed PMID: 29438574.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Protective effects of an extract of the freshwater microalga Scenedesmus rubescens on UV-irradiated skin cells. AU - Campiche,R, AU - Sandau,P, AU - Kurth,E, AU - Massironi,M, AU - Imfeld,D, AU - Schuetz,R, Y1 - 2018/03/14/ PY - 2017/09/11/received PY - 2018/02/07/accepted PY - 2018/2/14/pubmed PY - 2018/10/26/medline PY - 2018/2/14/entrez KW - Scenedesmus rubescens KW - UV irradiation KW - ageing KW - microalgae KW - skin SP - 187 EP - 192 JF - International journal of cosmetic science JO - Int J Cosmet Sci VL - 40 IS - 2 N2 - BACKGROUND: Skin ageing results from intrinsic but also extrinsic factors of which UV irradiation is a main cause. It is hence of interest to have means to protect skin from UV irradiation-induced damage. We selected an extract of the freshwater microalga Scenedesmus rubescens and assessed its potential to protect skin from photoageing caused by UV irradiation. METHODS: Skin cells in vitro and ex vivo were analysed for markers of UV irradiation-induced photodamage such as decreased viability, decreased collagen content, hyperpigmentation and sunburn cells. RESULTS: We found that a dry extract of the microalga Scenedesmus rubescens was able to suppress cellular signs of ageing induced by UV irradiation. It enhanced dermal fibroblast viability, rescued dermal collagen content, inhibited the formation of sunburn cells and inhibited tyrosinase activity. CONCLUSION: An extract of Scenedesmus rubescens showed broad activity against markers of UV irradiation-induced cutaneous ageing. It may therefore be used as a preventive or regenerative agent for anti-ageing strategies. SN - 1468-2494 UR - https://www.unboundmedicine.com/medline/citation/29438574/Protective_effects_of_an_extract_of_the_freshwater_microalga_Scenedesmus_rubescens_on_UV_irradiated_skin_cells_ L2 - https://doi.org/10.1111/ics.12450 DB - PRIME DP - Unbound Medicine ER -