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[Alpha-lipoic acid in the treatment of diabetic polyneuropathy].

Abstract

The issues of classification, pathogenesis, pathomorphology and treatment of diabetic polyneuropathy (DPN) are addressed. Pathogenetic mechanisms of the action of alpha-lipoic acid in treatment of DPN are justified. The authors present the results of randomized placebo-controlled trials of alpha-lipoic acid that revealed the high clinical efficacy and absence of side-effects even during the long-term treatment.

Authors+Show Affiliations

Pirogov Russian National Research Medical University, Moscow, Russia.Pirogov Russian National Research Medical University, Moscow, Russia.

Pub Type(s)

Journal Article
Review

Language

rus

PubMed ID

29460914

Citation

Chukanova, E I., and A S. Chukanova. "[Alpha-lipoic Acid in the Treatment of Diabetic Polyneuropathy]." Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova, vol. 118, no. 1, 2018, pp. 103-109.
Chukanova EI, Chukanova AS. [Alpha-lipoic acid in the treatment of diabetic polyneuropathy]. Zh Nevrol Psikhiatr Im S S Korsakova. 2018;118(1):103-109.
Chukanova, E. I., & Chukanova, A. S. (2018). [Alpha-lipoic acid in the treatment of diabetic polyneuropathy]. Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova, 118(1), pp. 103-109. doi:10.17116/jnevro201811811103-109.
Chukanova EI, Chukanova AS. [Alpha-lipoic Acid in the Treatment of Diabetic Polyneuropathy]. Zh Nevrol Psikhiatr Im S S Korsakova. 2018;118(1):103-109. PubMed PMID: 29460914.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Alpha-lipoic acid in the treatment of diabetic polyneuropathy]. AU - Chukanova,E I, AU - Chukanova,A S, PY - 2018/2/21/entrez PY - 2018/2/21/pubmed PY - 2019/3/14/medline KW - alpha-lipoic acid KW - diabetes mellitus KW - diabetic neuropathies KW - endothelial dysfunction KW - oxidative stress SP - 103 EP - 109 JF - Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova JO - Zh Nevrol Psikhiatr Im S S Korsakova VL - 118 IS - 1 N2 - The issues of classification, pathogenesis, pathomorphology and treatment of diabetic polyneuropathy (DPN) are addressed. Pathogenetic mechanisms of the action of alpha-lipoic acid in treatment of DPN are justified. The authors present the results of randomized placebo-controlled trials of alpha-lipoic acid that revealed the high clinical efficacy and absence of side-effects even during the long-term treatment. SN - 1997-7298 UR - https://www.unboundmedicine.com/medline/citation/29460914/[Alpha_lipoic_acid_in_the_treatment_of_diabetic_polyneuropathy]_ L2 - https://medlineplus.gov/diabeticnerveproblems.html DB - PRIME DP - Unbound Medicine ER -