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Cross-Sectional Survey of the Burden of Illness of Rosacea by Erythema Severity.
J Drugs Dermatol. 2018 Feb 01; 17(2):150-158.JD

Abstract

Rosacea is a chronic skin condition characterized by persistent central facial erythema. To explore the burden of illness of rosacea in US adults, a cross-sectional web-based survey was conducted. Participants answered questions on sociodemographics, clinical characteristics, bothersome symptoms, coping and avoidance behaviors, self-perceptions, and health care resource utilization, and completed 2 quality of life instruments, the 21-item rosacea-specific quality of life questionnaire (RosaQoL) and the 36-item Short Form Health Survey (SF-36). This paper reports the data from the 409 respondents with erythematotelangiectatic rosacea (ETR), analyzed by erythema severity. Mean age was 53.1 years; mild, moderate, or severe erythema was reported by 63.6%, 32.0%, and 4.4% of participants, respectively. Blushing/flushing and bumps/pustules were the most bothersome symptoms across severity subgroups. Participants in all subgroups coped with rosacea by applying make-up and managing their stress and anxiety, and tried to prevent rosacea flares by avoiding sun exposure, specific skin care products, and other triggers. Self-perceptions differed by severity subgroup: satisfaction with facial appearance significantly decreased, and worrying about how people will react and feelings of unattractiveness to others significantly increased, with greater erythema severity (all P less than 0.01). Treatment or assessment of rosacea was sought by 20% of participants in the past 3 months, most commonly from a dermatologist. Metronidazole was the most frequently prescribed topical product across severity subgroups, whereas doxycycline and other oral antibiotics were prescribed most frequently in the severe erythema subgroup. RosaQoL emotional domain scores increased with erythema severity (P equals 0.0035), but none of the SF-36 domain scores differed significantly by erythema severity. These results demonstrate that rosacea is associated with a substantial burden of illness that spans all levels of erythema severity in patients with ETR. Feelings of unattractiveness and the adverse impact of rosacea on emotional quality of life increased with erythema severity. J Drugs Dermatol. 2018;17(2):150-158.

Authors

Harper J
No affiliation info available
Del Rosso JQ
No affiliation info available
Ferrusi IL
No affiliation info available

MeSH

AdultAgedAged, 80 and overCohort StudiesCost of IllnessCross-Sectional StudiesErythemaFemaleHealth SurveysHumansMaleMiddle AgedRosaceaSeverity of Illness Index

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29462222

Citation

Harper, Julie, et al. "Cross-Sectional Survey of the Burden of Illness of Rosacea By Erythema Severity." Journal of Drugs in Dermatology : JDD, vol. 17, no. 2, 2018, pp. 150-158.
Harper J, Del Rosso JQ, Ferrusi IL. Cross-Sectional Survey of the Burden of Illness of Rosacea by Erythema Severity. J Drugs Dermatol. 2018;17(2):150-158.
Harper, J., Del Rosso, J. Q., & Ferrusi, I. L. (2018). Cross-Sectional Survey of the Burden of Illness of Rosacea by Erythema Severity. Journal of Drugs in Dermatology : JDD, 17(2), 150-158.
Harper J, Del Rosso JQ, Ferrusi IL. Cross-Sectional Survey of the Burden of Illness of Rosacea By Erythema Severity. J Drugs Dermatol. 2018 Feb 1;17(2):150-158. PubMed PMID: 29462222.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cross-Sectional Survey of the Burden of Illness of Rosacea by Erythema Severity. AU - Harper,Julie, AU - Del Rosso,James Q, AU - Ferrusi,Ilia L, PY - 2018/2/21/entrez PY - 2018/2/21/pubmed PY - 2018/8/30/medline SP - 150 EP - 158 JF - Journal of drugs in dermatology : JDD JO - J Drugs Dermatol VL - 17 IS - 2 N2 - Rosacea is a chronic skin condition characterized by persistent central facial erythema. To explore the burden of illness of rosacea in US adults, a cross-sectional web-based survey was conducted. Participants answered questions on sociodemographics, clinical characteristics, bothersome symptoms, coping and avoidance behaviors, self-perceptions, and health care resource utilization, and completed 2 quality of life instruments, the 21-item rosacea-specific quality of life questionnaire (RosaQoL) and the 36-item Short Form Health Survey (SF-36). This paper reports the data from the 409 respondents with erythematotelangiectatic rosacea (ETR), analyzed by erythema severity. Mean age was 53.1 years; mild, moderate, or severe erythema was reported by 63.6%, 32.0%, and 4.4% of participants, respectively. Blushing/flushing and bumps/pustules were the most bothersome symptoms across severity subgroups. Participants in all subgroups coped with rosacea by applying make-up and managing their stress and anxiety, and tried to prevent rosacea flares by avoiding sun exposure, specific skin care products, and other triggers. Self-perceptions differed by severity subgroup: satisfaction with facial appearance significantly decreased, and worrying about how people will react and feelings of unattractiveness to others significantly increased, with greater erythema severity (all P less than 0.01). Treatment or assessment of rosacea was sought by 20% of participants in the past 3 months, most commonly from a dermatologist. Metronidazole was the most frequently prescribed topical product across severity subgroups, whereas doxycycline and other oral antibiotics were prescribed most frequently in the severe erythema subgroup. RosaQoL emotional domain scores increased with erythema severity (P equals 0.0035), but none of the SF-36 domain scores differed significantly by erythema severity. These results demonstrate that rosacea is associated with a substantial burden of illness that spans all levels of erythema severity in patients with ETR. Feelings of unattractiveness and the adverse impact of rosacea on emotional quality of life increased with erythema severity. J Drugs Dermatol. 2018;17(2):150-158. SN - 1545-9616 UR - https://www.unboundmedicine.com/medline/citation/29462222/Cross_Sectional_Survey_of_the_Burden_of_Illness_of_Rosacea_by_Erythema_Severity_ DB - PRIME DP - Unbound Medicine ER -