Tags

Type your tag names separated by a space and hit enter

Cross Cultural Validation and Extension of the Clinical Assessment Interview for Negative Symptoms (CAINS) in the Chinese Context: Evidence from a Spectrum Perspective.
Schizophr Bull. 2018 10 15; 44(suppl_2):S547-S555.SB

Abstract

The Clinical Assessment Interview for Negative Symptoms (CAINS) was designed in accordance with the recent theory and research in social affective neuroscience and to address the psychometric and conceptual limitations of other instruments assessing negative symptoms. The present study aimed to provide a large-scale validation of the CAINS in China and examine its applicability and validity evidence across the schizophrenia spectrum. Using confirmatory factor analysis, our results replicated the original findings in the US development samples that the CAINS possesses a stable 2-factor structure, namely "motivation/pleasure" and "expression". We also found significant correlations between the CAINS and other negative symptom measures. The CAINS demonstrated good discriminant validity in differentiating negative symptoms in people with schizophrenia, nonpsychotic first-degree relatives and people with social anhedonia. People with schizophrenia exhibited significantly higher CAINS subscale scores than first-degree relatives and healthy controls. In addition, first-degree relatives had higher "motivation/pleasure" scores than healthy controls. The "motivation/pleasure" subscale scores of individuals with social anhedonia were also significantly higher than healthy controls.

Authors+Show Affiliations

Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, China. Department of Psychology, University of Chinese Academy of Sciences, Beijing, China.Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, China. Department of Psychology, University of Chinese Academy of Sciences, Beijing, China. North China Electric Power University, Beijing, China.Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, China. Castle Peak Hospital, Hong Kong Special Administrative Region, China.Peking University Sixth Hospital, Beijing, China. Peking University Institute of Mental Health, Beijing, China. Key Laboratory of Mental Health, Ministry of Health (Peking University), Beijing, China.Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, China. Department of Psychology, University of Chinese Academy of Sciences, Beijing, China. Haidian District Mental Health Prevent-Treatment Hospital, Beijing, China.Castle Peak Hospital, Hong Kong Special Administrative Region, China.Castle Peak Hospital, Hong Kong Special Administrative Region, China.Haidian District Mental Health Prevent-Treatment Hospital, Beijing, China.Shanghai Mental Health Centre, Shanghai Jiao Tong University School of Medicine, Shanghai, China.Castle Peak Hospital, Hong Kong Special Administrative Region, China.Department of Psychology, University of California, Berkeley, CA.Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, China. Department of Psychology, University of Chinese Academy of Sciences, Beijing, China.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Validation Study

Language

eng

PubMed ID

29471331

Citation

Xie, Dong-Jie, et al. "Cross Cultural Validation and Extension of the Clinical Assessment Interview for Negative Symptoms (CAINS) in the Chinese Context: Evidence From a Spectrum Perspective." Schizophrenia Bulletin, vol. 44, no. suppl_2, 2018, pp. S547-S555.
Xie DJ, Shi HS, Lui SSY, et al. Cross Cultural Validation and Extension of the Clinical Assessment Interview for Negative Symptoms (CAINS) in the Chinese Context: Evidence from a Spectrum Perspective. Schizophr Bull. 2018;44(suppl_2):S547-S555.
Xie, D. J., Shi, H. S., Lui, S. S. Y., Shi, C., Li, Y., Ho, K. K. Y., Hung, K. S. Y., Li, W. X., Yi, Z. H., Cheung, E. F. C., Kring, A. M., & Chan, R. C. K. (2018). Cross Cultural Validation and Extension of the Clinical Assessment Interview for Negative Symptoms (CAINS) in the Chinese Context: Evidence from a Spectrum Perspective. Schizophrenia Bulletin, 44(suppl_2), S547-S555. https://doi.org/10.1093/schbul/sby013
Xie DJ, et al. Cross Cultural Validation and Extension of the Clinical Assessment Interview for Negative Symptoms (CAINS) in the Chinese Context: Evidence From a Spectrum Perspective. Schizophr Bull. 2018 10 15;44(suppl_2):S547-S555. PubMed PMID: 29471331.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cross Cultural Validation and Extension of the Clinical Assessment Interview for Negative Symptoms (CAINS) in the Chinese Context: Evidence from a Spectrum Perspective. AU - Xie,Dong-Jie, AU - Shi,Hai-Song, AU - Lui,Simon S Y, AU - Shi,Chuan, AU - Li,Ying, AU - Ho,Karen K Y, AU - Hung,Karen S Y, AU - Li,Wen-Xiu, AU - Yi,Zheng-Hui, AU - Cheung,Eric F C, AU - Kring,Ann M, AU - Chan,Raymond C K, PY - 2018/2/23/pubmed PY - 2018/12/20/medline PY - 2018/2/23/entrez SP - S547 EP - S555 JF - Schizophrenia bulletin JO - Schizophr Bull VL - 44 IS - suppl_2 N2 - The Clinical Assessment Interview for Negative Symptoms (CAINS) was designed in accordance with the recent theory and research in social affective neuroscience and to address the psychometric and conceptual limitations of other instruments assessing negative symptoms. The present study aimed to provide a large-scale validation of the CAINS in China and examine its applicability and validity evidence across the schizophrenia spectrum. Using confirmatory factor analysis, our results replicated the original findings in the US development samples that the CAINS possesses a stable 2-factor structure, namely "motivation/pleasure" and "expression". We also found significant correlations between the CAINS and other negative symptom measures. The CAINS demonstrated good discriminant validity in differentiating negative symptoms in people with schizophrenia, nonpsychotic first-degree relatives and people with social anhedonia. People with schizophrenia exhibited significantly higher CAINS subscale scores than first-degree relatives and healthy controls. In addition, first-degree relatives had higher "motivation/pleasure" scores than healthy controls. The "motivation/pleasure" subscale scores of individuals with social anhedonia were also significantly higher than healthy controls. SN - 1745-1701 UR - https://www.unboundmedicine.com/medline/citation/29471331/Cross_Cultural_Validation_and_Extension_of_the_Clinical_Assessment_Interview_for_Negative_Symptoms__CAINS__in_the_Chinese_Context:_Evidence_from_a_Spectrum_Perspective_ L2 - https://academic.oup.com/schizophreniabulletin/article-lookup/doi/10.1093/schbul/sby013 DB - PRIME DP - Unbound Medicine ER -