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Correlations between changes in hematological indices of mothers with preeclampsia and umbilical cord blood of newborns.
Clin Exp Hypertens. 2019; 41(1):58-61.CE

Abstract

Preeclampsia is a condition that might severely impact the health of mothers and their newborns. The aim of this investigation is to examine hematological parameters in mothers with preeclampsia and umbilical cord blood. Eighty preecalmptic mothers were recruited in the study. In addition, eighty normal pregnant mothers served as controls. Hematological parameters that include hemoglobin (Hb), red blood cell count (RBC), red cell distribution width (RDW), packed cell volume (PCV), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), white blood cell counts (WBC), platelet counts, mean platelet volume (MPV) and Platelet large cell ratio (PLCR) were examined. Results showed a strong association between preeclampsia and low birth weight, premature/cesarean delivery and proteinuria (P < 0.001). Hb and neutrophils were significantly lower (P < 0.01), whereas RDW, PCV, MCV, MCH, MCHC and lymphocytes were significantly higher than normal ones (P < 0.01). When cord blood of preeclamptic mothers were compared with that of normal ones, similar findings were observed. In addition, results showed significant and positive correlations between preeclamptic mothers and their newborn in Hb (r2 = 0.075, P < 0.05), PCV (r2 = 0.084, P < 0.01), MCV (r2 = 0.077, P < 0.05), MCHC (r2 = 0.115, P < 0.01), RBC (r2 = 0.086, P < 0.01) and retics (r2 = 0.306, P < 0.01). In conclusion, changes in several hematological parameters associated with preeclampsia were correlated in affected mothers and their newborns. Such biomarkers can be used to predict pregnancy outcomes in women with preeclampsia.

Authors+Show Affiliations

a Department of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences , Taibah University , Medina , Saudi Arabia. c Faculty of Medical Laboratory Sciences , Sudan University for Sciences and Technology , Khartoum , Sudan.a Department of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences , Taibah University , Medina , Saudi Arabia. b Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences , Jordan University of Science and Technology , Irbid , Jordan.c Faculty of Medical Laboratory Sciences , Sudan University for Sciences and Technology , Khartoum , Sudan. d Department of Medical Laboratory , Al- Ghad College of Applied Medical Sciences , Medina , Saudi Arabia.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29473761

Citation

Elgari, Mahmoud M., et al. "Correlations Between Changes in Hematological Indices of Mothers With Preeclampsia and Umbilical Cord Blood of Newborns." Clinical and Experimental Hypertension (New York, N.Y. : 1993), vol. 41, no. 1, 2019, pp. 58-61.
Elgari MM, Khabour OF, Alhag SM. Correlations between changes in hematological indices of mothers with preeclampsia and umbilical cord blood of newborns. Clin Exp Hypertens. 2019;41(1):58-61.
Elgari, M. M., Khabour, O. F., & Alhag, S. M. (2019). Correlations between changes in hematological indices of mothers with preeclampsia and umbilical cord blood of newborns. Clinical and Experimental Hypertension (New York, N.Y. : 1993), 41(1), 58-61. https://doi.org/10.1080/10641963.2018.1441861
Elgari MM, Khabour OF, Alhag SM. Correlations Between Changes in Hematological Indices of Mothers With Preeclampsia and Umbilical Cord Blood of Newborns. Clin Exp Hypertens. 2019;41(1):58-61. PubMed PMID: 29473761.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Correlations between changes in hematological indices of mothers with preeclampsia and umbilical cord blood of newborns. AU - Elgari,Mahmoud M, AU - Khabour,Omar F, AU - Alhag,Samaher M, Y1 - 2018/02/23/ PY - 2018/2/24/pubmed PY - 2019/1/29/medline PY - 2018/2/24/entrez KW - Hypertension KW - biomarkers KW - cord blood KW - preeclampsia KW - pregnancy SP - 58 EP - 61 JF - Clinical and experimental hypertension (New York, N.Y. : 1993) JO - Clin. Exp. Hypertens. VL - 41 IS - 1 N2 - Preeclampsia is a condition that might severely impact the health of mothers and their newborns. The aim of this investigation is to examine hematological parameters in mothers with preeclampsia and umbilical cord blood. Eighty preecalmptic mothers were recruited in the study. In addition, eighty normal pregnant mothers served as controls. Hematological parameters that include hemoglobin (Hb), red blood cell count (RBC), red cell distribution width (RDW), packed cell volume (PCV), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), white blood cell counts (WBC), platelet counts, mean platelet volume (MPV) and Platelet large cell ratio (PLCR) were examined. Results showed a strong association between preeclampsia and low birth weight, premature/cesarean delivery and proteinuria (P < 0.001). Hb and neutrophils were significantly lower (P < 0.01), whereas RDW, PCV, MCV, MCH, MCHC and lymphocytes were significantly higher than normal ones (P < 0.01). When cord blood of preeclamptic mothers were compared with that of normal ones, similar findings were observed. In addition, results showed significant and positive correlations between preeclamptic mothers and their newborn in Hb (r2 = 0.075, P < 0.05), PCV (r2 = 0.084, P < 0.01), MCV (r2 = 0.077, P < 0.05), MCHC (r2 = 0.115, P < 0.01), RBC (r2 = 0.086, P < 0.01) and retics (r2 = 0.306, P < 0.01). In conclusion, changes in several hematological parameters associated with preeclampsia were correlated in affected mothers and their newborns. Such biomarkers can be used to predict pregnancy outcomes in women with preeclampsia. SN - 1525-6006 UR - https://www.unboundmedicine.com/medline/citation/29473761/Correlations_between_changes_in_hematological_indices_of_mothers_with_preeclampsia_and_umbilical_cord_blood_of_newborns_ L2 - http://www.tandfonline.com/doi/full/10.1080/10641963.2018.1441861 DB - PRIME DP - Unbound Medicine ER -